First Trimester Screening For Down Syndrome Possible, NICHD-Funded Study Finds
...o sometimes referred toas Trisomy 21, is a genetic abnormality resulting from either an extra copy ofchromosome 21 or from an extra portion of the long arm of the chromosome. Therisk of the condition increases sharply with maternal age. For women under age30, the risk of conceiving a fetus with Down syndrome is...ONYX Pharmaceuticals Reports Phase II Clinical Trial Results At ASCO Meeting
...utations in p53 are the most common typeof genetic abnormality in cancer, occurring in more than 50 percent of humancancer cases, including more than 70 percent of recurrent and refractory cancersof the head and neck. Onyx Pharmaceuticals was founded in 1992 for the purpose of discovering anddeveloping novel th......ve revealed that the BCR-ABL protein is theobvious abnormality to attack in CML." Druker stressed that the development of this new cancer- fighting drugrepresents an example of the fundamental importance of determining the molecularmechanisms that drive cell growth in specific diseases. Once that is unde......todetermine the exact mechanisms that underlie the abnormality revealed in thestudy. Ernst is a member of the Society for Neuroscience, an organization ofmore than 27,000 basic scientists and clinicians who study the brain and nervoussystem. The Society publishes The Journal of Neuroscience....Some CFS Patients Benefit From Low-Dose Steroid, But Side Effects Too Risky
...ith CFS manifest neurally mediated hypotension, an abnormality of bloodpressure control. Preliminary published data suggests that treatment withfludrocortisone, a steroid drug that helps the body retain salt and water, mightbe beneficial. The current study - which is still open to recruitment - istesting fludr...Heart Valve Abnormalities Examined In Relation To Duration Of Diet Drug Use
..., the greater the likelihood that they showed some abnormality on anechocardiogram," said Duke cardiologist Dr. Thomas Ryan. He added that most of the cases of aortic regurgitation noted by theresearch team were graded as "trace or mild. In our clinical experience, mostpatients with mild aortic regurgi...UF Researchers Cite Possible Link Between Autism, Schizophrenia And Diet
...thesis sitting out there today isthat some genetic abnormality is causing these disorders. It is certainlypossible that these genetic abnormalities could lead to the metaboliceffects Dr. Cade mentions, though there is not substantial support for thatat this time. "With autism in particular, there are thr...Ordinary Touches Multiply Into Severe Pain For Fibromyalgia Patients
...gical abnormality, but that there is aneurological abnormality present." Staud, who presented his research findin...ud and colleagues found the central nervous system abnormality byconducting a series of repetitive stimulation tests on people with thesyndrome as well as healthy ...Birthmarks best treated with red laser light
...characteristic port-wine colour. This type of skin abnormality can be treated using photo-selectivethermolysis, during which the area is irradiated with laser light of a particular colour; this isabsorbed well by the blood but not by the rest of the skin. The light energy absorbed is convertedinto heat, which ca...Rosenbaum discovers "hidden clue" on cardiogram
...t high risk for ventriculararrhythmia, a heartbeat abnormality that triggers sudden cardiac arrest. Unfortunately, many of these patients who undergoECG tests eventually join the ranks of the 300,000-plus Americans who die annually from sudden cardiac arrest, the mostcommon cause of death in the country. That gr...Scientists show hormone involved in cryptorchidism
...ism - impaired testicular descent - is acongenital abnormality that affects 2 percent to 3 percent of full-term humanmales at birth. Scientists at UT Southwestern Medical Center at Dallas havefound, in mice, that a hormone is involved in the regulation of testiculardescent. Their experiments, reported in the Jul...MGH study shows mitral valve prolapse not a stroke risk factor
...eral Hospital report that mitral valveprolapse, an abnormality of a heart valve, does not appear to be associated withan increased risk of stroke among young people. Earlier studies, many usingoutdated imaging techniques, had led to the belief that mitral valve prolapsewas a significant risk factor for stroke. ...Mitral valve prolapse less common, less harmful than previously thought
...-valveprolapse is the most common cardiac valvular abnormality in industrializedcountries," said Dr. Lisa Freed, the study's lead author. "In addition, the lowfrequency of associated complications may allay anxiety for those in whommitral-valve prolapse is diagnosed in an outpatient setting," she said. D...Oxygen reduces effects of retinal detachment
...etachment reduced all aspects of this type of cell abnormality inducedby detachment. The two articles represent a collaboration between the laboratories ofJonathan Stone, D.Sc., at the NSW Retinal Dystrophy Research Center, Departmentof Anatomy and Histology, University of Sydney, and Steven Fisher, Ph.D...'Silent stroke' linked to depression
...ion between depressionand 'silent stroke,' a brain abnormality that can lead to a stroke. In a studypublished today in Stroke: Journal of the American Heart Association,researchers say individuals who develop depression after age 50 should beevaluated for stroke. A silent stroke occurs when small blood vessels ...NICHD funded researchers discover gene for Rett syndrome
... months of age. Specifically, the genetic abnormality responsible for Rett syndromeinterferes with the operation of one of the many biochemical switches thatregulate how genes are expressed. The researchers found that the disorderresults from the mutation of the gene that makes methyl cytosine binding ...UF study shows contemporary method accurately predicts cancer risk
...istory also strongly correlated with the degree of abnormality and breast cancer development. Masood said she hopes her research will pave the way for an expanded study involving multiple academic medical centers. Ultimately, her goal is to save lives. Detecting cancer at an earlier stage is associated with an i...Hospital stays of three days for uncomplicated heart attack
...hey found 16 patients suffered from a severe heart abnormality called ventricular fibrillation and three died, but the other 13 survived because they received emergency treatment in the hospital. Had they been at home, the researchers projected that all 16 would have died. Since these 16 patients could no...Brain scans of Gulf War veterans show brain damage
...yndrome 2. "Finding the same level of brain cell abnormality in the veterans from a different branch of service and a different part of the country increases the likelihood that the findings are widespread among the nation's veterans," Haley said. In 1997 Haley and his colleagues defined three Gulf War syndr...UCSD researcher wins grant to study colon cancer in African-Americans
...ty, called microsatellite instability (MSI). This abnormality is associated with colorectal cancer development, ...rethers' laboratory has shown that cells with this abnormality do not respond to the widely used chemotherapeutic agent 5-fluoruracil (5-FU). The researchers will...