New study tests amitriptyline for painful bladder syndrome
...drink and avoid bladder irritants such as alcohol, acidic foods and carbonated or caffeinated drinks. Staff and patients will find out who received the amitriptyline when the study is finished. Medications and tests are free to participants. Although amitriptyline is primarily used for depression, the way i...International trial of two microbicides begins
...fluid that neutralizes the vaginal environment. An acidic environment inactivates HIV as well as other pathogens. Each woman in the trial will be placed at random into one of four equally sized groups. One group will use BufferGel before each act of sexual intercourse, one group will use PRO 2000, one group...News briefs from the Journal CHEST, November 2004
...lassic reflux symptoms were found to have abnormal acidic reflux. The study appears in the November issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians. EMERGENCY CARE WORKERS MOTIVATE ASTHMA PATIENTS TO BECOME EDUCATED Emergency department (ED) professionals can help ...Mayo Clinic finds ketogenic diet may be started as an outpt treatment for children with epilepsy
...presence in the blood of abnormally high levels of acidic substances. In the study, Mayo Clinic researchers used the Rochester Epidemiology Project medical records-linkage system to locate all diagnoses involving the ketogenic diet from 1963-1975. The system index allows the identification of all medical...Excess body weight linked to formation of uric acid kidney stones, UT Southwestern researchers find
...the types of foods eaten. "Larger people have very acidic urine even when they control their diets," said Dr. Sakhaee, professor of internal medicine at UT Southwestern. "Other studies we have done in the GCRC support this concept. For the first time, we are advising weight loss as part of our therapy. That...Rare disease endemic in South America is model for studying autoimmunity
...mercury in their skin, nails, hair and urine. The acidic soil of El Bagre is naturally rich in minerals, metalloids and trace elements. However mercury, which has been shown in the laboratory to trigger an autoimmune response in animals with the right genetics, is present because it's used in gold mining. ...What do bad breath, hot dogs, and gastric blood flow have in common? The nitrite anion
...ate is reduced to nitrite by oral bacteria. In the acidic environment of the stomach, nitrite is further reduced to nitric oxide, which has broad biological activity. In the January 2 issue of the Journal of Clinical Investigation, Jon Lundberg and colleagues from the Karolinska Institute in Sweden tested t...New blood test could detect lung cancer in its earliest stages
...ause it can detect proteins of low molecular mass, acidic or basic, and at concentrations much lower than other methods. "Using a MALDI-TOF MS platform is a particularly exciting advance because current diagnostic tools -- such as PET and CT scans -- have had no obvious impact on lung cancer mortality rate ...Surface treatments could make ready-to-eat products safer
... the fact the material was acidic, and it remained acidic throughout the storage period, he said. Listeria can be introduced from the environment or from personnel in a meat-processing plant. Some of the outbreaks often have involved factors such as remodeling in a plant that made the organism air-borne...Ouch! The receptors mediating acidic pain sensation
...ASICs are severely deficient in their responses to acidic stimuli, controversy remains about the function of ASICs in mammals. In a study reported in the October 21 issue of the Journal of Clinical Investigation (JCI) by Shinya Ugawa and colleagues from the Nagoya City University Medical School, Japan, the ...New technology tested at Stanford offers unique view inside small intestines
...g like this." Not only does it traverse the highly acidic stomach, but the camera successfully peers through the soupy contents of the small intestine and takes pictures as it tumbles along. "It doesn't matter if you're looking where you're going, or where you've been," said Van Dam, explaining that the tum...Polymer could allow oral delivery of insulin to diabetics
...can potentially overcome these barriers. The less acidic environment of the small intestine allows the polymer to swell and release the insulin, explains Foss. Moreover, the polymer intercepts calcium, which the wall of the small intestine needs to keep the pores in the walls tightly sealed. Once the pores...Researchers closer to delivering new insulin pill for diabetics
...istered orally because they are broken down in the acidic environment of the stomach. To get around this co...insulin inside, for at least two hours in a highly acidic stomach-like environment. That would be enough time for them to pass from the stomach into the intes...Drugs made from polymers, the stuff of plastics
... PolyAspirin™ allows it to dodge the stomach's acidic environment and break down into salicylic acid later - primarily when it hits the intestine's alkaline environment, where it is absorbed. As a result, the medication is delivered more efficiently and sticks to its target better, Uhrich says. This cou...UB scientists discover role of melatonin in bone formation
...matrix proteins such as secreted protein, which is acidic andrich in cycteine, known as SPARC; osteocalcin, and alkaline phosphatase, or ALP, the researchers found. Most significantly, said Roth, further experiments showed that the mousepre-osteoblasts responded to normal body levels of melatonin, ...Emerging Pathogens And Safety Of Fresh Produce Key Issues Facing Food IndustryAnd Scientists
...tion process, the latterincrease their survival in acidic foods, decrease their inactivation in thestomach, and increase their virulence. Strains often associated with foodborneoutbreaks, such as Escherichia coli O157:H7, are among the most acid-resistant. This resistance also enables pathogens to resist o...