Cranfield joins the UN fight against land mines
...ight week management programme for local land mine action managers. It is being run by the Cranfield Humanitarian Mine Action Unit (CMA) and run on behalf of the United Nations Development Programme (UNDP) with funding from the UK Government's Department for International Development (DFID). Land mines are ...UI-led study shows experimental anti-cancer drug also has anti-HIV properties
...make proteins. Flavopiridol effectively blocks the action of an enzyme called P-TEFb, which controls one of ...ons of flavopiridol were effective at blocking the action of P-TEFb. P-TEFb is required for transcription of the HIV-1 genome to occur. Flavopiridol inhibits...Chemist uses DNA to trigger an alternative chemotherapy method
...tead of using the nucleic acid as a target for the action of a drug, we use nucleic acid as a trigger. It's better to use genetic information as a trigger than as a target." Ma described the method in a paper delivered at the annual meeting of the American Chemical Society, Aug. 20, 2000, in Washington, ......hat the oral liquid has a similarly rapid onset of action as an intra-muscular injection and is as efficacious.(1) In the prospective, "naturalistic" study, 60 acutely psychotic patients treated in the emergency room of a large, urban medical centre were given either Risperdal oral solution (2 mg) in com......state cancer treatment to help block production or action of the male hormones that have been shown to fuel prostate cancer. ...NIH awards grant to MetaPhore Pharmaceuticals to study novel pain treatments
...oxide and oxygen. This product of SOD's catalytic action also has potential benefits that complement those of free radical removal. Hydrogen peroxide has been shown to be critical to the functioning of white blood cells in killing foreign bacteria. "SOD mimetics have major medical potential, based on the...Unique collaborative service established for childhood allergy-related anaphylaxis
...gency medication available at school, an emergency action plan, or a teacher or carer on site able to admini...y signs and symptoms, and an appropriate first aid action plan needs to be in place," Dr Gold said. "Furthermore, we have also shown recently in a separate...Many uninsured adults do not receive needed medical care
...nment or most states. Concerted and collaborative action by policymakers and health care professionals will be required to address these persistent needs," they conclude....More protests against abortion pill
...pharmaceuticals from you." RU486 blocks the action of the hormone progesterone, causing the lining of the uterus to break down. Taken two days later, misoprostol makes the uterus contract and the cervix dilate, helping to expel the embryo. But now it seems even the company that makes misoprostol is g......as a once-a-day dose. It has a longer duration of action than any other treatment for Parkinson's disease, giving proven symptom and fluctuation control over 24 hours.2...FDA awards grant to metaphore pharmaceuticals to study septic shock in humans
...roxide and oxygen. This product of SODs catalytic action also has potential benefits that complement those of free radical removal. Hydrogen peroxide has been shown to be critical to the functioning of white blood cells in killing foreign bacteria. SOD mimetics have major medical potential, based on th...European commission grants "orphan" status for new acute myeloid leukaemia treatment
...esident, Wyeth-Ayerst Research. "Its mechanism of action focuses on using antibody-antigen specificity to target delivery of potent chemotherapy to myeloid leukaemic cells. This compound represents the first product from Wyeth's promising oncology pipeline." As a designated orphan medicinal product, Mylot...Cell degradation is topic of science review
...s of self-digestion of cell components through the action of enzymes within a cell, plays a vital role in cell maintenance and development, but in recent years has also been linked to a growing number of human diseases, including neurodegenerative conditions, cardiovascular disease and breast cancer. ...Sustained use of anti-depressants increases cell growth and protects cells in the brain
...mans laboratory has been studying the mechanism of action of anti-depressants in rodents for over 15 years. The researchers have focused on cellular actions of anti-depressants, looking at the role of the intracellular signal transduction pathways that control neuronal function. They have identified several...Novartis receives FDA approval for Starlix, a new treatment for type 2 diabetes
...how that Starlix has a "fast on, fast off" mode of action on the beta-cell (the cell in the pancreas that produces insulin) that stimulates rapid, short-acting insulin secretion, addressing a basic defect in type 2 diabetes. In addition, Starlix does not cause late hyperinsulinemia which reduces the risk o...New research expands understanding of treatment for ADHD
...it hyperactivity disorder (ADHD), its mechanism of action and its effects on the human brain have been poorly understood. In an article in the January 12 online issue of the Journal of Neuroscience, researchers have for the first time assessed the effects of therapeutic doses of oral Ritalin on the levels ......ent identification of a receptor mediating Nogo-66 action should greatly facilitate the development of agents with pharmaceutical potential in a diverse group of neurological conditions, such as spinal cord injury, brain trauma, stroke affecting white matter, and chronic, progressive multiple sclerosis," he...Knocking heads is part of the rough and tumble action of a football game, but few things can sideline an otherwise healthy athlete faster than a concussion. To study the long-term effects of concussions, NFL Charities, an organization of the member clubs of the National Football League, has awarded a $1...Beyond Viagra: other phosphodiesterase inhibitors are candidates for potential therapies
...tion of other PDEs. "We use Viagra's mechanism of action as a beautiful example of drug and physiological selectivity when we talk to students," Beavo says. Researchers are now seeking other PDE inhibitors that will also act selectively, without toxic side effects throughout the body. Since many PDEs hav......for developing new ways to "see" the structure and action of molecules - fundamental achievements that have led to new strategies for chemotherapy, for example. He will receive the 2001 Award for Creative Invention from the American Chemical Society at its 221st national meeting in San Diego. Baldeschwieler...