New Approach To Multidrug Resistance
...that is, tumors become better able towithstand the actions of a wide variety of unrelated chemicals. The anti-drugpump is a major tool in multidrug resistance. The researchers have found a novel way to suppress production of the pump longenough for cancer drugs to work. Therapies for cancer treatment often...Cardiovascular Costs, Deaths Projected To Rise In 1998
...good news is that people can takelifestyle-related actions to lower their levels of cholesterol - actions such asbecoming physically active and eating a diet low in saturated fat andcholesterol. Medical tre...Diuretic Drugs May Have Clot-Busting Effects
...ulate the heart andconstricts the blood vessels -- actions that can raise blood pressure. Thescientists found that chloride, a mineral naturally found in the body, canrestrict epinephrine. Since diuretics work by helping to block chloride, thesedrugs indirectly may affect epinephrine -- and thereby help pre...Hospitals Discourage Consumer Questioning Of Bills, Study Suggests
...study's conclusions were that (1) these preemptive actions may helporganizations avoid the need for more public and risky forms of impressionmanagement; (2) negative images, in some cases, may actually be beneficial toorganizations; and (3) organizations sometimes use anticipatory impressionmanagement to avo...New Drug Prevents Breast Cancer In Postmenopausal Women, UCSF Researchers Report
...trogenreceptor modulators (SERMS), which block the actions of estrogen in sometissues, such as the breasts, and mimic estrogen in other tissues, such as thebones. "During the clinical trials of raloxifene, we saw twice as many cases of breastcancer develop among women taking placebo compared to those taking......newer antidepressants are not as specific in their actions astheir manufacturers claim. Simon Wessely, professor of psychiatry at King's College London, agrees."There's tremendous uncertainty about how they work," he says. "The publicthinks the doctors know, but they don't. Any decent psychopharmaco...Parenting CD-ROM Helps Reduce Children's Behavioral Problems
...ies are holding parents accountable for theillegal actions of their children. Cities in Ohio, Michigan and Oregon are amongmany that have passed or are considering parental responsibility acts. "Parents have the greatest amount of influence over these children andif we can do something to teach paren......opamine throughout the brain." Thesewide-ranging actions can cause side effects such as irritability, insomnia, ordepression. In future studies, the researchers plan to determine the affect of ageon the finding. "We want to find out whether children with ADHD have the sameabnormalities present in...Novel Therapy To Treat Lung Cancer Patients Enrolling Patients At UCSF Cancer Center
...s of therapies that have been shown to inhibit the actions of anatural body chemical, called Matrix Metalloproteases (MMPs), that breaks downthe material between cells to make room for new cellular growth. There is good reason for enthusiasm about this drug because the preliminarydata looks favorable and s......trogen receptormodulators (SERMS), which block the actions of estrogen in some tissues, such asthe breasts, and mimic estrogen in other tissues, such as the bones.Raloxifene is similar to other SERMS, such as tamoxifen, because it has apositive, estrogen-like effect on a woman's bones and cholesterol levels....New approach supercharges immunotherapy
...helper cells, so called because theycoordinate the actions of the entire immune system." This is the only system currently in use that favors the growth of T-helpercells over cytotoxic cells. A few weeks after receiving their new, improved T-helper cells, some patientshave experienced fevers and lethargy whi...Views Of Tamoxifen And Synthetic Estrogen In Action Provide Clues For Designing Better Drugs
... like estrogen in some tissues butblock estrogen's actions in others. The best known SERM is tamoxifen, whichrecently received FDA approval for breast cancer prevention. But tamoxifen is flawed. It may block the potentially harmful action ofestrogen in the breast, preserve estrogen's beneficial effects for b......complaints have been registered or if disciplinary actions havebeen taken against a physician. In California, this information is available bycalling the Medical Board of California at 1-800-633-2322. If you prefer, youcan also visit their website at www.medbd.ca.gov. 4. Get acquainted. Take some time to ...Tobacco Control Is Global Challenge, WHO Director Says
...wmillions of victims in your home countries. Those actions will help prevent thecost of treating hundreds of thousands of cancer and heart disease patients frombreaking the back of your health systems in the coming decades," she said....Early warning signs of violence often overlooked, study finds
...oubledchildren are likely to take life-threatening actions either toward others orthemselves. Hazler has given workshops within schools across the country to helpadults recognize the difference between bullying and non-bullying situations andwhat intervention methods to use in prevention of school vi......ction of a single enzyme. Also, they can study the actions of drugson each enzyme needed for human steroid production. "All human cells handle cholesterol, whereas yeast contains no cholesterol,"Auchus explained. "The value of using yeast cells, instead of human cells, forthese studies is that we can put in......for promoting growth in childhood,it has important actions in adults. It regulates body fat, increases muscle massand capacity for aerobic exercise, and may support normal mood and cognition.Some effects are carried out by stimulating increased production of insulin-likegrowth factor-I (IGF-I) in the liver a...... and strikes, but puts forth other reasons whysuch actions might not stand on solid moral ground. For example, Goold writes, some argue that physicians should not strike becausethey are professionals. Airline pilots and teachers, she replies, areprofessionals, too, yet they are organized and routinely strike...UK researcher develops nicotinic drugs with R.J. Reynolds
...ences, Crooks has investigated the pharmacological actions ofseveral nicotine metabolites and nicotine analogs on the brain have beeninvestigated. Nine patents on the nicotine analog work have been licensed fordevelopment by Targacept, and several others recently have been filed with theU.S. Pate......and his colleagues reasoned that blocking CTLA-4's actions on immune cellsknown as T lymphocytes might allow the killer cells to destroy the cancerouscells rather than fade away after the tumor repels their initial attack. Toaccomplish this, the investigators raised a monoclonal antibody against CTLA-4and ad...