New Colorectal Cancer Treatment Available
...institution and others that CPT-11 is safe and has activity in some patients when used in a second line settin...ogether. "We are very encouraged by the anti-tumor activity of CPT-11 which has been found in patients who have received prior therapy as well as those who did ...KUMC Researchers Announce Breakthrough Method For Predicting Epileptic Seizures
... occurs. EEGs are tools used to measure electrical activity within the brain. By using the algorithm, research...is imminent. "The algorithm measures brain activity and separates the signals into seizure and non-seizure components. This creates a ratio of seizure t...Drug And Radiation Treatment May Shrink Pancreatic And Gastric Tumors
...rised to find the regimen demonstrated substantial activity in thepatients. The result was tumor reduction in 70 percent of the patients withstomach cancers and 31 percent of those with pancreatic cancers. Most pancreatic and stomach tumors are hard to detect at an early stage.When they are found, the tumor...Duke Study Uses Tiny Temperature Changes To Probe Water-Exclusion At Protein Binding Sites
...ny biological processes within ourbodies, from the activity of enzymes to the signaling that takes place withincells. And blocking these binding events using synthetic molecules is thebasis of action of almost all pharmaceutical compounds, Toone said. Chemical reactions in the body typically unfold when...Researchers Gain Insights Into Drugs Used For Manic-Depression
...late release of a chemical thattriggers brain cell activity responsible for helping control the wild moodswings of bipolar disorder. Used together, the drugs may achieve a desiredoutcome without causing dangerous side effects. Some three million Americans suffer from bipolar disorder,consisting of ma...Studies Find Public Policies For Children And Teenagers Not Very Effective
... School-Based Sex Education Because sexual activity has increased so much among highschool age students in the last 25 years, school-based sexeducation was introduced to help children manage their sexualbehavior. But it hasn't worked very well, say psychologists whohave found that the sex education cu...Antioxidant-Enhancing Drug Partly Rescues Noise-Induced Hearing Loss
...rbs free radicals. R-PIA was found toincrease the activity of glutathione, thus providing enhanced protection...e hearing center in the cortex. The lack of brain activity inresponse to normal sound indicated complete hearing loss. Brain-wave activity was measured...Common Drug-Capsule Coating Not As Inert As Previously Thought
...rs biological activity-- or the lack of biological activity -- are incorrect, you can easily headoff in a wrong direction. We need to take a closer look at what fundamentalmaterial properties generate desired biological responses." PEG's changing configuration may provide a vital clue, Leckband said. "We ar......inton administration to coordinateExecutive Branch activity with tribes through a Domestic Policy Council WorkingGroup chaired by Secretary Babbitt, there has not been the kind of systematicreview of how the current structure and function of Federally funded Indianprograms fits the realities face by Indian pe...Researchers Finding May Boost Effectiveness Of Anti-HIV Drugs
... Drugs are already available to suppress the activity of Pgp. They havebeen developed over the past 10-20 years because Pgp is also expressed by manycancer tumors. Pgp inhibitors have been used to boost the effectiveness ofchemotherapy in these tumors. Kim said he would like to study the effecti...American Heart Association Comment: Lancet (Jan. 24, 1998) Report
...n that helps form clots) and factor VIIcoagulation activity (an indication of the viscosity of the blood). The study found that compared to placebo, warfarin reduced heart attack by 21percent and heart attack deaths by 39 percent; low-dose aspirin reduced heartattack risk by 20 percent and reduced heart attac...Bi-Monthly Boosts Of Aspirin Benefit Heart
...ld initially "neutralize" the platelet stimulatory activity of thered blood cells. Subsequent blood tests found that after about two weeks, thered blood cells "escaped from this initial inhibition and began to stimulateplatelets again," says Marcus. To maintain inhibition, a booster dose of 3...Are Deprived Areas A Greater Drain On Out Of Hours Workload?
(Relation of out of hours activity by general practice and accident and emergency ser...lisle et al investigate the level of our of hours activity in six general practices and the sole accident and emergency department in Nottingham. The authors ...New Math, High-Tech Imaging Solving Old Riddle: How Does The Brain Operate When We Think?
... type of fMRI the team used shows changes in brain activity due toincreases ordecreases in oxygen concentratio...uracy of their math by comparing normalanimalbrain activity to abnormal activity caused by decreased oxygen in the blood. Theteam loweredthe amount of oxygen in...Exercise, Classroom Instruction Cut Kids' Cholesterol, Study Finds
...the 1995-96 school yearthey received both physical activity and classroom training, either one or theother "intervention" or neither. Physical activity was vigorous and sustained three times a week but didnot require special sports skills. Classroom te......ly administered Karenitecinhad excellent antitumor activity against solid tumors (prostate, colon, breast,lung...motherapy and does not interfere with theantitumor activity of cisplatin. There appears to be reproducible evidence ofpotentiation or enhancement of cisplatin...Effects Of Physical Activity On Preterm Birth
... physicalactivity related to three areas: physical activity of daily life, whether athome or work; leisure-tim...y percentlower risk of preterm delivery. Physical activity solely related to the women'sjobs did not appear to have any adverse effect on their pregnancy. -end...Increased Public Access To Defibrillation Could Prove Potentially Cost-Effective And Life-Saving
...n additional 20,000 lives annually. Recent activity in state legislatures shows that there is movement toexpand access to AEDs. In Florida, legislation was recently signed into lawthat allows an AED to be used by any person for the purpose of saving the lifeof an individual having a cardiac arrest. ...Researchers Identify Candidate Immunosuppressant With Fewer Side Effects
...'ability to design new drugs to interfere with its activity and suppress theimmune system. Editors, please note: a diagram of the immune system signaling pathway isavailable....UB Plants "Seeds" By Investing In Research Projects; Researchers Leverage Investment 14 Times Over
...ear. "The program has spurred the kind of research activity that ought to be taking place in a research university," he said. "It's good for the people of New York State and the United States because they'll be deriving benefits from the research we're doing." By distributing small, one-time grants on a comp...