Safer estrogen targets painful intercourse in older women
...ike the normal estrogen molecule, the new compound acts only on the tissue to which it is applied, reducing risks and providing a potentially safer alternative, the researchers say. They suggest that the modified estrogen could be particularly helpful in treating vaginal atrophy in women for whom estrogen...Study points to potential role for caffeine in reducing the risk of Parkinsons disease
...ogy at MGH and principal investigator. Caffeine acts as an antagonist to the A2A receptor, blocking its binding site and rendering it inactive. The scientists found that the effects of caffeine were mimicked by several known A2A antagonists as well as by genetic inactivation of the A2A receptor. The ...Studies find eating fruits and vegetables good for lungs
...nown whether the beneficial effects of these foods acts in the same way throughout a persons life or whether the effects are limited to, or stronger in, particular periods such as early in life or in childhood. "To try to sort this out we have been conducting a nine-year follow-up of this population, and ...Study offers hope for chocolate-loving reflux disease sufferers
...erson who does not suffer from GERD, the sphincter acts as a valve and allows substances to go from the esophagus down to the stomach only. In GERD sufferers, the sphincter does not function properly, allowing acid and other substances in the stomach to pass back up to the esophagus. The researchers found...Extreme precipitation linked to waterborne disease outbreaks
... 2105 watersheds in the United States. A watershed acts as the drinking water source for the encompassing area. The city or county where each outbreak occured was also recoded to its corresponding watershed. The researchers found that 51 percent of the outbreaks were preceded by extremely high levels of p...Psychologists identify best aggression-prevention programs in schools
...rget both boys and girls and focus on the everyday acts of aggression that occur on school playgrounds and... mild forms of aggression, and later, more serious acts of violence, prevention and early intervention programs should target pre-school and elementary scho...Behavioral therapies plus pharmacotherapies can add up to success
... federal Food and Drug Administration. Naltrexone acts as an opioid antagonist within the opioid neurotransmitter system, which is a part of the brain's reward system. When opioids are stimulated, levels of a neurotransmitter called dopamine are increased. Dopamine activity is thought to be key to expe...Brown researchers find new photoreceptor and visual system in the eye
... researchers have found a new cell in the eye that acts as a photoreceptor like a rod or cone and sets the bodys circadian clock. For nearly 150 years, scientists considered rods and cones to be the eyes only photoreceptors cells that turn light energy into electrical impulses. Many cells in the eye an...Hormone therapy for breast cancer - the treatments of the future
...ve oestrogen modulator or SERM. Although tamoxifen acts largely as an antioestrogen in breast cancers it actually exhibits pronounced oestrogenic activity when oestrogen levels are very low," said Professor Dowsett. He said there were data from laboratory studies that supported published clinical evidence...MGH study finds herceptin has additional antitumor qualities
... it has multiple anti-angiogenic effects and so it acts like a cocktail of angiogenesis-blocking drugs," says Rakesh Jain, PhD, director of the Steele Laboratory for Tumor Biology, the report's senior author. Scientists and physicians have been trying for years to block a tumor's ability to secrete factor...Study shows synthetic pheromone in womens perfume increases intimate contact with men
...02 Womens perfume laced with synthetic pheromones acts as a sexual magnet and increases the sexual attractiveness of women to men, San Francisco State University researchers conclude in a study appearing in the current issue of the quarterly journal Physiology and Behavior. The study, the first of its ki...Outsmarting cancer - new results from novel enzyme inhibitors
..., as laboratory studies indicate that the new drug acts synergistically with conventional treatments to boost their effectiveness. R115777 is one of a novel drug class called farnesyl transferase inhibitors, he told a news briefing at the 3rd European Breast Cancer Conference in Barcelona. Farnesyl trans...Miniature filtering device to make angioplasty safer being tested
...ilter with holes about 140 microns in diameter and acts much like a net, catching debris while allowing blood to continue flowing during the procedure. In standard angioplasty, a wire stent and balloon are threaded through the femoral artery in the groin to the area in the chest where the blockage occu...Nicotine patches and gum may pose health hazards
...on atom, is the first example of a metabolite that acts as a catalyst for chemical reactions, the researchers said. The researchers demonstrated that nornicotine could interact with many important chemical reactions, including the conversion of glucose into energy. Impairment of glucose metabolism has bee...New findings about brain's 'compass' offer clues about Alzheimer's
... known as the medial superior temporal area (MST) acts much like a compass, instantly updating your menta...raduate student Michael Froehler show that the MST acts not only as a compass but also as a sort of biological global positioning system, providing a mental...Allergens and viruses act together to worsen asthma
...ma, indicating that domestic exposure to allergens acts synergistically with viruses in allergic patients, increasing the risk of hospital admission, say the authors. Strategies directed at viruses and reducing exposure to allergens are needed, they conclude....Parenting News: More than one hour of TV a day may lead to violence, Science study suggests
...e teens and early twenties to engage in aggressive acts against other people, researchers found. This was ...e than three hours per day. Three to five violent acts occur in an average hour of prime-time television, and 20 to 25 violent acts occur in an average hou...Buck Institute researcher identifies new drug targets for Alzheimers disease
... Scissors?" she said. "We want to find a drug that acts like a rock against those scissors, to block the cutting action of the scissors." "This paper is important because it provides a novel molecular target to discover drugs to treat AD. Indeed, unlike the beta-secretases that have been recently cloned ...Testosterone aids older mens brains, UCSF study says
...levels. This study doesnt explain how testosterone acts on the brain, Yaffe said, but other studies of mice have shown that the parts of the brain that handle learning and memory tasks are replete with receptors for testosterone. In comparing scores, the researchers focused on bioavailable testosterone,...Enzyme halts muscle waste in mouse models of most-common childhood muscular dystrophy
... in DMD patients. Normally, CT GalNAc transferase acts as a chemical stimulant to generate scaffold-like tissue at the neuromuscular junction. In research reported earlier this year in the journal Developmental Biology (242, 58-73), Martin and his team described the role of CT GalNAc transferase and the...