New compound that acts on peripheral receptors may be treatment for some nerve pain
... study in mice and rats show that a compound which acts on a specific type of cell receptor found only out...he activity of a new compound called AM1241, which acts on CB2 cannabinoid receptors. "This is one of the two types of receptors on which THC, the active in...Study calls for major reforms in marketing of ephedra
... of this Asian herb is ephedrine, a stimulant that acts similarly to amphetamines. The Federal Trade Commission (FTC), which is responsible for regulating product advertising, developed advertising guidelines that include substantiating marketing claims and disclosing potential safety issues. However, of ...Taking painkillers during pregnancy increases risk of miscarriage
...an embryo to miscarriage. In contrast, paracetamol acts only in the central nervous system, which may explain why it has no effect on risk of miscarriage, explain the authors. These findings will need confirmation, say the authors. Meanwhile, it may be prudent for physicians and women who are planning to ...Study: Stereotypes prevail in media coverage of depression
...ssion/sports -- mostly in relation to high-profile acts of violence committed by men who were using SSRIs, or acts of aggression by high-profile athletes such as Mike Tyson. Very few articles addressed how depressio...Study raises prospect of practical vaccine for metastatic melanoma
...lls are then re-injected into the patient. GM-CSF acts like a magnet for agents of the immune system, drawing an attack on melanoma cells throughout the body, not just those that contain the GM-CSF gene. When tumor samples from vaccinated patients are viewed under a microscope, cancer-fighting cells are ...Mayo Clinic study shows melatonin helps alleviate violent sleep disorder symptoms
...eve. "Therefore, if a person has violent dreams or acts out the dreams, it is worthwhile to see a clinician for this. If there is potential for injury, then a patient should be evaluated -- see a sleep clinician and undergo a sleep study for diagnosis and treatment. You want to make sure you know what you...New cholesterol fighter found in red wine
... to resveratrol, a compound found in grapes, which acts as an antioxidant. But saponins could be just as important. "Saponins are a hot new food ingredient. People are just starting to pay attention to it," says study leader Waterhouse. "No one ever thought to look for it in wine." The compounds are beli...Combining osteoporosis drugs produce no added benefit
...f growth and resorption into the body. Parathyroid acts to both promote bone growth and accelerate its resorption and is initially more active in promoting bone growth, the researchers said. Thus they hypothesized that, as compared with parathyroid hormone therapy alone, the combination of parathyroid hor...Post-Sept. 11 study results published by U. of Colorado Center
...t of community crises brought about by intentional acts designed to terrorize our society," Tierney said. "Sept. 11, 2001 sends a powerful message about the need to enhance the ability of society and its institutions to prepare, respond and recover from large-scale disasters, whatever their causes." ...Scientist gets award for sending people to sleep
...finding that xenon, an inert anaesthetic gas, also acts to prevent damaged nerve cells from dying after events such as a stroke. If clinical trials progress as hoped, it is expected that patients with acute nerve injury may benefit from their basic research into anaesthetic mechanisms. Professor Maze comm...Enigmatic role for NF-kappaB in the hardening of arteries
...ipids such as low-density lipoprotein (LDL), which acts as a carrier for cholesterol and fats in the bloodstream. Modification of these lipids induces inflammatory processes, which recruit macrophages from the blood that consume LDL, thereby creating lesions that ultimately cause vessel narrowing and rest...Rabies remains a costly public health threat, says Jefferson virologists
...s that researchers "need to find out how the virus acts at the molecular level. Then we may be able to devise a drug against it." In the meantime, new research continues to look for safer, less expensive and more effective vaccines, a particular concern for developing nations....OHSU doctors use 'putty' to prevent hemorrhagic stroke
...said. Clark, who says the Onyx material looks and acts like "squishy rubber cement," believes the new procedure will have significant advantages over invasive brain surgery and, perhaps, coiling. "Whether it's better than coiling, that's what the study is evaluating," he said. "It certainly looks very pr...Brain signals from the paralyzed or injured captured by computer
...n-board processor, and a two-way radio link, which acts as a telemeter. A microprocessor interacts with the two-way radio link and can be remotely programmed to detect and sort the neural signals received by the prosthetic device. The device is designed to be placed under the skin on the skull and connect...Antidepressants decrease chronic pain by inhibiting TNF production in brain, UB researchers find
...erception of pain," said Spengler. Norepinephrine acts similarly to adrenaline, which is released from the adrenal gland in response to arousal and stress, such as might occur during combat, for example. Increases in adrenaline enable persons to perform necessary functions in spite of increased fear or s...Elements of green tea prevent HIV from binding to human T cells
...n CD4 molecules on human T cells. The CD4 molecule acts as a binding target for HIV vesicles and plays an important role in the aggressive infection process. Researchers found that EGCG showed a strong affinity for the CD4 molecule, and by binding them, could effectively prevent the binding of the HIV gly...JCI Table of Contents, November 14, 2003
...otential cell targets for anti-CD154 and how CD154 acts to reduce SLE disease. TITLE: Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions AUTHOR CONTACT: Peter E. Lipsky National Institutes of Health, Bethesda, Maryland, USA. Phone: 301-49...Surgically placed 'sling' reduces signs of aging in the neck
...ins to droop is because the underlying muscle that acts as a kind of "sling" has stretched over time and can no longer support the tissues under the chin. Several plastic surgery procedures have been used to combat the signs of aging in the face and neck area, including face lifts and liposuction. Walla...Researchers use crippled poliovirus to attack brain cancer
... "In cancer cells, the IRES from rhinovirus acts as the trigger that activates gene expression, but the genes being expressed -- the silver bullets in the gun, so to speak -- are all from the poliovirus," said Gromeier. "The polio proteins kill the cancer cells quickly and efficiently." ...American Thoracic Society Journal news tips for January 2004 (first issue)
...cule of the constitutive innate immune system that acts as a recognition agent for endotoxins.) Although about one-third of all children wheeze in the first year of their life, many of these conditions are transient in nature. However, for a subgroup that wheezes repeatedly, the condition is associated w...