Coupling of brain proteins may prompt new treatments for schizophrenia, addiction
... of the symptoms associated with schizophrenia and addiction are caused by either too much or too little dopami...Many of the negative symptoms of schizophrenia and addiction are regulated by D1-like receptors. Niznik and his team of researchers demonstrated that dopamine ......addicts who are actively working to overcome their addiction would want to do that. Kosten is currently conducting a Phase 11a dose escalation trial involving cocaine addicts in an out-patient treatment program. Once this is complete, a dose will be selected for pivotal efficacy trials, which will aim to ev...New study underscores effectiveness of methadone maintenance as treatment for heroin addiction
...ling, is a far more effective treatment for heroin addiction than is simply the temporary use of methadone to detoxify patients and reduce drug craving, even when the detoxification is coupled with much more intensive psychosocial therapy. The study is published in this week's Journal of the American Medical ...Behavioral sensitization: A new perspective on alcoholism
...difficult to distinguish when, in the continuum of addiction development, sensitization and tolerance may develop and/or co-exist. Hodge speculated that sensitization might occur early on in an individual's exposure to a drug like alcohol, but noted that several ethical and practical considerations would impe...Common pathway found in early stages of addiction to alcohol and many drugs
...have discovered that a key step leading to alcohol addiction can be blocked by preventing alcohol from gaining ... of addiction. The search for a drug to prevent addiction will have to go beyond MK-801, Hodge pointed out, since the compound itself would probably be addict...Drug that curbs nicotine craving may do same for cocaine
...It's always very exciting when a drug used for one addiction has implications for a broader range of addictive drugs," said Levin, whose study was funded by the National Institutes of Health. Mecamylamine is an older medication originally used to treat high blood pressure. Researchers now know it blocks...National summit on pain management to discuss new standards for pain assessment and treatment
...ted by common misperceptions about pain medication addiction and tolerance. To increase knowledge and stimulate greater collaboration among U.S. health care leaders, the Joint Commission on Accreditation of Healthcare Organizations and the American Pain Society will convene the Leadership Summit on Pain Manage...Acupuncture is promising treatment for cocaine addiction, Yale researchers find
... study supports the use of acupuncture for cocaine addiction and shows that alternative therapies can be combined with the arsenal of Western treatments for fighting addiction," said Arthur Margolin, the study's principal investigator and research scientist in psychiatry at Yale School of Medicine. "This promi...Fine-tuning naltrexone treatment for alcoholics
...picelli. "They provide more evidence that alcohol addiction is a medical disease, and medicines like naltrexone can be helpful in helping people recover."...NIDA clinical toolbox provides the latest information about drug treatment strategies
... country will benefit from years of drug abuse and addiction research thanks to the NIDA Clinical Toolbox: Scie...e state-of-the-art research information about drug addiction and its treatment," explained Dr. Alan I. Leshner, NIDA Director. "Our understanding of drug abuse ...High success rates for variety of heroin addiction treatment medications
...0 mg.) were much more effective in treating heroin addiction than low-dose methadone maintenance (20 mg.). LAAM and methadone are available for clinicians to prescribe. Buprenorphine is currently under review by the Food and Drug Administration and is used only in research studies. There are nearly one ...Drinking and drugging can be painful
...iction is a brain disease," she said. "Too often, addiction is treated as a moral issue, or a 'defect' in some..., there is still a great deal of stigma related to addiction and substance abuse. In fact, the very term 'substance abuse' somehow implies that the person with ...Scientists find link between dopamine and obesity
..., NY -- Dopamine, a brain chemical associated with addiction to cocaine, alcohol, and other drugs, may also play an important role in obesity. According to a study by scientists at the U.S. Department of Energy's Brookhaven National Laboratory, obese people have fewer receptors for dopamine, a neurotransmitter...Methadone may cause potentially fatal arrhythmia, Georgetown researchers find
... whether the reported arrhythmias were due to drug addiction or some other factor, said Raymond L. Woosley, MD, PhD, associate dean of clinical research at Georgetown Medical Center. However, our data clearly show that methadone has the same pharmacologic actions that are seen with other agents known to cause ...Drug war strategy: First fund enforcement then switch to treatment, says O.R. paper
...s the average annual rate of initiation of cocaine addiction between 1972 - 1992 (averaging about 1 million new addicts a year, but varying widely over time), the baseline price of cocaine (about $110 per pure gram in base year 1992), and the average number of users in 1992 and 1993 (6.5 million). The authors ......iment to initiating HAART therapy, while methadone addiction treatment among men, health insurance, and access ... that men enrolled in methadone treatment for drug addiction were 80 percent more likely to enroll in HAART than those that were not on methadone, however there ...Study shows weight loss with an antidepressant medicine in combination with lifestyle intervention
..., renal, gastrointestinal, or psychiatric disease, addiction to nicotine or recent cessation of smoking, use of weight loss agents in the past three months, or history of alcohol or substance abuse. All patients maintained a moderate exercise regimen in addition to a reduced-calorie diet (600 fewer calories pe...Annals of Internal Medicine, tip sheet, March 5, 2002
...s not effective in treating ringing in the ears or addiction to alcohol, tobacco or chemicals. Several clinical trials have come to contradictory conclusions on its effectiveness in treating chronic pain, back pain and headache. Acupuncture appears relatively safe, if practiced by trained acupuncturists. It ca...Lack of inhibition strengthens nicotine addiction
...e finding helps scientists understand why nicotine addiction takes root so quickly and lasts so long. In 2000, ...ld be difficult to design a better drug to promote addiction to this horrible habit, said neurobiologist Daniel McGehee, Ph.D., assistant professor in the depart...Examining the effects of managed care on alcohol and other drug treatment
...If patients don't get enough treatment, then their addiction will continue and any money spent on treatment may be wasted. In the same way, if patients get more treatment than they really need, money is also wasted. We hope to continue research on the latest edition of the ASAM Criteria by studying their use...