Heart failure deaths reduced by 30 percent
...ion of ahormone known as aldosterone should not be administered in conjunction with anACE (angiotensin-converting-enzyme) inhibitor. "Not only was combination therapy with Aldactone and ACE inhibitors welltolerated by patients in the most severe stages of heart failure, but thedecrease in cardiac death and hospit...Duke/Novalon researchers identify potential mechanism behind tamoxifen resistance in breast cancers
...though the pocket forms from the time tamoxifen is administered to thecell, the researchers believe that tamoxifen resistance begins when the elusiveprotein binds to this new site. What happens next to cause resistance isunclear, but researchers have shown they can block resistance by plugging up thepocket with o......GF or toreduce VEGF production. Currently, VEGF is administered by injection or catheterinto the heart. Dr. Levy's team would like to find a simple delivery method thatinvolves an oral pill. "The body has the ability to heal itself. Our goal is to help it do thatmore easily," he said....Combination immune therapy kills melanoma in mice
...ors raised a monoclonal antibody against CTLA-4and administered it to mice with various types of cancer. "CTLA-4 blockade using this monoclonal antibody worked, but notparticularly well in anything but the least aggressive types of tumors,"said Allison. "We wanted something that would work in tumors that are har......Clinical data have demonstrated that Sonata can be administered as needed,immediately before going to bed or after the patient has gone to bed and hasexperienced difficulty sleeping -- provided patients have four or more hours inbed before becoming active again. According to clinical studies, Sonata is notassoci...Aging hearts need social support
...archers measured participants' blood pressures and administered a 40-itemquestionnaire designed to reveal levels of social support. They completedsurveys relating to neuroticism, extraversion, aggression, depression, stress,life satisfaction, and their health behaviors. The scientists report theresults of their...Heart failure deaths reduced by 30 percent with new drug regimen
...ion of ahormone known as aldosterone should not be administered in conjunction with anACE (angiotensin-converting-enzyme) inhibitor. Not only was combination therapy with Aldactone and ACE inhibitors welltolerated by patients in the most severe stages of heart failure, but thedecrease in cardiac death and hospi...New HIV drug intervention cheap and effective
...mbination of AZT and the antiviral drug lamivudine administered late in pregnancy (PETRA, Arm-A) and at labor (PETRA, Arm-B). The model assumed each treatment program was given to 20,000 hypothetical pregnant women in sub-Saharan Africa. It took into account various factors such as rates of HIV infection, breast...Health plays a crucial role in California labor market, according to UCSF researchers
...isability over a one-year period. The 1999 survey, administered to 2,044 Californians (18 years of age and older), included 913 adults who participated in the first survey in 1998. Findings of the 1999 survey show that the labor market continues to be strong. More than 70 percent of working age adults are curr...Poor health is a major factor for early retirement, according to UCSF researchers
...ng, served as the project director. The survey was administered May 1-July 9,1999. Survey findings of older Californians show: Almost three out of five (58 percent) are not retired. Almost a quarter are completely retired. One out of eight (12 percent) arepartially retired. More than half (51 percent) of the ......f all symptoms before returning to play. The tests administered in thisstudy allow us to thoroughly measure brain function and make more informeddecisions." Dr. Collins continues: "And for players who have sustained more than oneconcussion over their career, we need to be even more cautious because our studyshowe...Turning off cancer shield may allow safer cancer therapy
...e effects would allowhigher doses of therapy to be administered to improve cure rates.To identify a compound that could block the action of p53, the researcherscreated a model of normal tissue containing a reporter gene that turns cellsblue when p53 is activated. They treated the cultured mouse cells with 10,000m...Some HIV patients show no viral rebound after stopping drugs
...S. A vaccine having this effect could possibly be administered to infectedpopulations in the third world who do not have access to antiretroviral pills."Our study suggests that such a vaccine will have to stimulate cell-mediatedimmune responses against HIV," says Douglas Nixon, M.D., Ph.D., senior author onthe p...Drug offers new hope for victims of cardiac arrest
...t-of-hospital cardiac arrest. The drug was administered to 504 people in Seattle and surrounding KingCounty, Wash., who suffered cardiac arrest due to a dangerous heart rhythm(ventricular fibrillation) and were treated at the scene by Medic One. Patientsranged in age from 20 to 94 years. The majority were...UNC-CH nutrition expert says nation should regulate some diet supplements
...ial products," the scientist said. "Forsupplements administered at doses that can be found in foods, adoption of GoodManufacturing Practices (rules proposed by the U.S. Food and Drug Administrationfor manufacturers) should not significantly alter availability." For nutraceuticals that expose humans to ing...Yale Medical School to begin clinical trial for glaucoma medication
... causes of blindness around the world, soonwill be administered at Yale Medical School in a clinical trial. ...given 10 milligrams of memantine, onethird will be administered 20 milligrams, and one third will be given a placebo,Dr. Shields said. "The study will go on for fou...New treatment for type 2 diabetes puts insulin back to work
...s and regimens, regardless of whether the drug was administered to patients previously treated with an anti-diabetic agent or with diet alone. These studies indicate that rosiglitazone is effective regardless of the starting level of glucose control. *HbA1c is haemoglobin A1c haemoglobin that has reacted with gl...UNC studying new drug against ovarian and endometrial cancers
...mal.Moreover, the drug is given orally rather than administered through intravenousinfusion. "Traditional chemotherapy is usually cytotoxic; it kills cells. And whenit kills cancer cells, it kills some of your healthy cells," says Dr. Linda VanLe, associate professor of obstetrics and gynecology at UNC-CH...Telemedicine can be used for accurate diagnosis of stroke symptoms
...erapy, speedy treatment is essential and should be administered wherever thepatient is. Because physicians with the expertise to determine the best treatment optionsfor stroke patients are primarily located in tertiary care hospitals,telemedicine - the exchange of data and information via electronic means tofaci...