Other highlights in the August 20 issue of JNCI
...up to 30% of pheochromocytomas (rare tumors of the adrenal gland) are hereditary--a percentage more than double that previously estimated. In the review, Jennifer Bryant and Katherine L. Nathanson, M.D., of the University of Pennsylvania, and their colleagues examine the data on the association of germline m...Cedars-Sinai researchers detail events that enable brain tumors to weaken immune system
... believe glucocorticoids, hormones produced by the adrenal glands, are involved in the loss of thymocytes. T...release of glucocorticoids. In rats that had their adrenal glands removed to reduce the production of glucocorticoids, the damaging effects were significantly ...Study suggests that tomboys may be born, not made
...and her co-authors note that girls with congenital adrenal hyperplasia (CAH), a genetic disorder involving prenatal exposure to high levels of male hormones, tend to prefer masculine-typical toys and activities. The study results appear in the November-December issue of Child Development. Participants were p...Pituitary tumor cells in Cushings syndrome found to express large amounts of protein receptor
...ssure. These effects are caused by high levels of adrenal steroids, or cortisol. The disorder is commonly treated with surgery to remove the tumor, but tumors are not always completely removed, either because they are too small to detect or have spread to parts of the brain that cannot be accessed via surg...Hypertension is study focus of $10 million NIH grant to MCG
... increases aldosterone," a hormone produced by the adrenal gland to get the kidneys to absorb more sodium, he said. "Which is the initiator? Where is the original abnormality? Once you find out what that abnormality is, you can find therapies to target that. That's my goal," Dr. Harshfield said. Another goa...Behavior plays key role in disease development and control, according to 10-year prospective review
...epression can provoke the release of pituitary and adrenal hormones that have multiple effects on immune function and can lead to actual health changes. Coronary Heart Disease - Coronary heart disease (CHD) is the leading cause of death in the United States and over the past decade there has been an increa...Update on national asthma guidelines released
..., such as reduced bone mineral density, suppressed adrenal function, and increased incidence of cataracts are not considered significant risks for children. "Asthma is a complex disease," adds Dr. James Kiley, director of the NHLBI Division of Lung Diseases. "Research has led to numerous medications that...Impaired sodium excretion after stress contributes to hypertension in blacks
... stimulates aldosterone, a hormone produced by the adrenal gland that also gets the kidneys to absorb more sodium. If the blood pressure drops because of bleeding or a stressful situation triggers the basic survival instinct to fight or flee, these are some primary ways the body increases blood pressure. Dr....Hormone therapy for breast cancer - the treatments of the future
...ovaries but by converting hormones produced by the adrenal gland into oestrogen via an enzyme called aromatase. A class of drugs called aromatase inhibitors is effective in older women. "The latest, third generation aromatase inhibitors, anastrazole (Arimidex), letrozole (Femara) and exemestane (Aromasin), c...American Thoracic Society Journal news tips for March (first issue)
...mily. It is the principal hormone secreted by the adrenal glands, and is a potent anti-inflammatory agent. Cortisol demonstrates a circadian rhythm with its peak in the body at 8 a.m. and its lowest level around midnight. Although the pathogenesis of nocturnal airwayobstruction is still unclear, the autho......Clinic Womens HealthSource. Womens ovaries and adrenal glands share the responsibility for testosterone production. Studies show that testosterone helps women maintain muscle and bone strength, and contributes to sex drive or libido. Women manufacture about one-seventh the amount of testosterone each ...Testosterone skin patch improves sexual functioning in surgically menopausal women
... Women produce testosterone in their ovaries and adrenal glands and may require sufficient levels of the hormone for proper sexual functioning. About half of a woman's testosterone comes from the ovaries, and as a result women whose ovaries are removed before menopause lose about half their natural te...Parenting, stress and your child's risk for alcoholism
...al with humans. These monkeys also have a similar adrenal system which, for the purposes of this study, means that they respond to stress like humans do. In addition, primates have very complex societies; they create social groups, they have rules about social behavior, and they are (under normal circumsta...How long-term alcohol consumption can damage the immune system
...ers the body's circulation, travelling down to the adrenal glands (located at the top of the kidneys), causing them to produce corticosteroids. The corticosteroids then enter the blood circulation, where they 'guide' the body's redirection of nutrients - including glucose - to those parts of the body that a......es she's producing, either from her ovaries or her adrenal glands, it could have the same effect." Male rat pups whose mothers received genistein also experienced early onset of puberty. Normal puberty in a rat life cycle begins about two weeks after weaning. "Whatever the clocks are in the brain that contro...Estrogen-driven gene activates human pituitary tumors, Cedars-Sinai Medical Center researchers find
...es pivotal to growth and reproduction, thyroid and adrenal function. This finding builds on the landmark 1997...for understanding human development, reproduction, adrenal and thyroid function, and pituitary cancer. Pituitary tumors are more common in women than in men, r...Sleep debt affects metabolic functions
...hormones of the hypothalamus, and the pituitaryand adrenal glands. At the end of the sleep-debt conditions, glucose concentrations in the bloodwere higher than in the fully rested conditions, and concentrations ofthyrotropin, which regulates the release of thyroid hormones, were lower. Cortisol concentration...Researchers develop better means to diagnose adrenal gland tumors
...o detect potentially deadly tumors that form inthe adrenal glands has been shown to be significantly more sen...evelop tumors in a number of organs, including the adrenal glands that sitatop the kidneys. "Pheochromocytoma can occur in VHL patients as young as 8 years of......hatturns yeast cells into little versions of human adrenal glands, have learned theanswer: they have shown ho...ast cells, converted into little versions of human adrenal glands, as ascientific model to study the action of the human enzymes that are involved insex steroi...Some CFS Patients Benefit From Low-Dose Steroid, But Side Effects Too Risky
...wever, was modest, and there was clear evidence of adrenal suppressionby the drug." Twelve of 33 patients on the therapy developed laboratoryevidence of adrenal insufficiency. "It was manageable and completelyreversible," says Dr. Straus, "but it's the kind of...