DNA Imaging to Design Better Drugs
... of the new assay is it shows researchershow drugs affect single DNA molecules, said Dr. Lawrence Bottomley, aGeorgia Tech chemistry professor who specializes in scanning forcemicroscopy. "Other techniques require us to examine several billion molecules ata time and then make inferences about the behavior ...Testosterone May Affect Learning Skills; May Be Put In Tablet Form
...erapy report that the primary male sex hormone may affect some learning skills, including improving visual and perceptual abilities. The findings may provide additional insight into testosterone's role in the brain. "This is an interesting, early finding and it highlights the importance of studying the effe...Discovery Hints At Multitude Of New Targets For Drugs
...cording to McDonnell, the discovery of new ways to affect such receptorscould produce significant changes in the strategies by which pharmacologistsseek new drugs to modulate them. "To target drugs to one body tissue, pharmacologists have traditionallylooked for subtypes of a receptor unique to tha...Early Menopause Stress Related In Developing Countries
...enstruation -- may be due to the same things that affect runners and anorexics." Menopause naturally occurs when a woman's ovaries have no follicles left that can develop to release fertile eggs. Because women have a set number of follicles that begin to undergo atresia -- degeneration and resorption ...Substance from Grapefruit Juice May Make Medications Safer
...CYP3A4 levels between individuals, which, in turn, affect their metabolism of drugs. Thus, a dose of a drug that may be effective for one individual can be toxic to another. Addition of the active substance in grapefruit juice to a medication could produce a drug for which a standard dosage would be equal...New Approach To Multidrug Resistance
...atrelatively low doses of these DNA-damaging drugs affect genes selectively. Genesactive in day-to-day housekeeping -- for example, those involved in cellstructure or basic food metabolism -- are less vulnerable to damage than genesinduced in response to external signals -- such as hormone fluctuations or ...Diuretic Drugs May Have Clot-Busting Effects
...lping to block chloride, thesedrugs indirectly may affect epinephrine -- and thereby help prevent theformation of dangerous blood clots, says the study's lead author, WarrenLockett, M.D., professor of medicine and endocrinology at Wayne State UniversitySchool of Medicine, Detroit. "The goal of treat...Airport Noise Can Seriously Affect The Health And Psychological Well-Being OfChildren
... The constant roar from jet aircraft can seriously affect thehealth and psychological well-being of children, according to a new CornellUniversity study. The health problems resulting from chronic airport noise,including higher blood pressure and boosted levels of stress hormones, theresearchers say, may h...Tighter Chemical Binding = Better Meds
... modifies the compound and computes how thechanges affect the drug's binding ability. The 3-D structures of hundredsof key human proteins have been solved in recent years, many of them byYale scientists, making rational drug design possible. Jorgensen also has developed widely used computer programs, such......e compensated in medical groups does not appear to affect the cost or amountof health services for patients....chers identifiedseveral factors that did appear to affect cost and use of health services. These included patient's age and gender, health plan benefit level ...ACS Industry Pavilion Features Chemistry's Cutting Edge
...ent firms who willdiscuss trends and how they will affect chemical industry careers. The IndustryPavilion also will feature literature, networking and computer resources. Brochures on the Industry Pavilion's programs and displays are availablein the ACS Press Room, Rm. 202 of the Dallas Convention ...Drug Is First In Decade To Show Promise Treating Generalized Anxiety Disorder
...ost common form of mental illness in America. They affect more than 23million people, about the same number of Americans who have depression. Thedirect and indirect costs associated with anxiety disorders in the U.S. were$46.6 billion in 1990, nearly one-third of the nation's total mental health billof $148...National Health Study Launched On The Internet
...s a scarcity of scientific information on how they affect health. "Wehave included many of these supplements...to test how exercise,diet, and dietary supplements affect disease risk. All information providedwill be strictly confidential. Over the previous six years, W...Poor Heart Disease Patients Pay More For Medications, Get Less Preventative Care
...ts," Tung said. "We focused on howlower income may affect how long people live." Patients with less than nine years of education and an income of lessthan $10,000 per year also were older, more likely to be female and had morehypertension. Frequently, these patients are living on a fixed income wit...UB Plants "Seeds" By Investing In Research Projects; Researchers Leverage Investment 14 Times Over
... Medical Sciences to study how chemicals in plants affect heart function in fruit flies in order to examine how such chemicals might affect cardiac function in humans. Original UB investment: $20,000 Orville T. Beachley, Jr., Ph.D., associa...New Drug Prevents Breast Cancer In Postmenopausal Women, UCSF Researchers Report
... in participating women by 87 percent; and did not affect the riskof estrogen-receptor negative cancer. Approximately two-thirds of breast cancers in postmenopausal women areestrogen-receptor positive. These cancer tumors' cells contain a protein, orreceptor, that responds to estrogen, stimulating tissue ...ONYX Pharmaceuticals Reports Phase II Clinical Trial Results At ASCO Meeting
... not limited toits Annual Report on Form 10-K, may affect the actual results achieved by thecompany....Metrifonate, A New Alzheimer Drug, Helps Behavior Problems
... wasconvenient to take just once a day and did not affect liver function. Only 12percent of those who took it left the study because of nausea, diarrhea or otherside effects. "This metrifonate study shows that this class of drugs can benefitpatients with mild or moderate Alzheimer's disease, at leas...Health Risk To "Cigarette Babies" Is Neglected, Duke Scientist Charges
...ls ofnicotine is still present at doses that don't affect growth. The brain is muchmore sensitive than the rest of the body," said Slotkin. Nor should the medical community or the public blindly accept thepopular myth that crack cocaine causes more severe damage. "A major point is that virtu......cant trends in clinical practicethat may adversely affect quality of care. MMI's systematic approach helpshealthcare organizations focus their limited resources on key areas of risk,such as serious patient injuries and diagnostic error, in an effort to reducemedical mistakes and improve patient safety. "Fo...