Beyond Viagra: other phosphodiesterase inhibitors are candidates for potential therapies
...PDEs are thought to mediate other processes. PDE3 affects insulin secretion (with potential involvement in diabetes) and leptin signaling (with dietary and fat implications). Researchers at drug companies and other universities are examining how PDE inhibitors may be used to improve memory, treat chronic o...Largest ever overactive bladder study published in leading urology journal
...) for overactive bladder, a medical condition that affects millions of adults worldwide, including 17 million in the U.S. alone. Overactive bladder is marked by symptoms of frequent urination, and urgency with or without urge incontinence (wetting episodes). Overactive bladder is a disruptive but treatable...Brain's efforts to save itself during Alzheimer's may backfire
...ifferent things in different parts of the body. It affects the body's secretions of growth and reproductive hormones, and may regulate food intake and body weight. It also plays a role in peripheral nerves and organs. Scientists have known that galanin has something to do with learning and memory and is invo......e health of individuals over a long period of time affects the work they do, how much they work, their purcha... Salud in Igatimi, Paraguay to study how ethnicity affects the connections between health and economic outcomes among indigenous populations. The researchers ......(IDH), or very low blood pressure. This condition affects 20 to 50 percent of dialysis patients and can cause nausea, vomiting, dizziness and even life-threatening symptoms such as abnormal heart rhythms and diminished blood supply to the heart and brain. These side effects often cause patients to stop trea...UT Southwestern researcher finds beta-blocking drug reduces heart failure in blacks
..., as a treatment for heart failure, a disease that affects 3 percent of all black adults in the United States... a group of people (blacks) with a bad disease. It affects them worse than anyone else, and we've never really known if there is any therapeutic strategy that ......study shows that money is not the only factor that affects whether uninsured seniors take their prescription drugs. "Forgoing medications for lack of coverage is a very real phenomenon. This study calls attention to the magnitude of this problem, particularly among certain disadvantaged communities," said......iated with osteoporosis and vaginal dryness, which affects about 40 percent of women within 10 years of the onset of menopause. But fear of side effects such as breast and edometrial cancer and stroke cause many women to steer clear of HRT. Hochberg said the risks associated with HRT outweigh the benefits...Double-drug therapy may benefit some multiple sclerosis patients
...MS is a disease of the central nervous system that affects the brain and spinal cord. It strikes an estimated 250,000 people in the United States and is the major acquired neurologic disease in young adults. Common signs and symptoms of MS include fatigue, psychological and cognitive changes, weakness or pa...Tai chi can reduce arthritis pain, pilot study finds
...cted joint and decreases the adverse mental health affects related to living with arthritic pain," Adler says. Although the benefits of exercise are clear, getting the elderly involved in an exercise class is still a challenge. "Often older people will not come to class, because they're afraid they're goin...NCEP issues major new cholesterol guidelines
...llitus, is the most common form of the disease and affects more than 14 million Americans. A lipoprotein profile as the first test for high cholesterol. A lipoprotein profile measures levels of LDL, total cholesterol, HDL, and triglycerides, another fatty substance in the blood. The prior recommendati......ir drug regimens. Nonalcoholic fatty liver disease affects nearly 1 in 4 in the United States Current scientific evidence suggests that nonalcoholic fatty liver disease (NAFLD) can progress to liver fibrosis and eventually to cirrhosis. In Europe and Asia, estimates of the prevalence of the disease range fro...Researchers gain insights on pulmonary fibrosis
...age at diagnosis is 58), and that it predominantly affects Caucasians (92 percent). The researchers believe that, like most diseases, the cause of pulmonary fibrosis will likely be a complex interplay between susceptibility genes and environmental factors, such as inhaled agents or dusts. While the resea...... and lower-extremity amputations. Type 2 diabetes affects approximately 200 million people worldwide. Forty to fifty percent of patients with Type 2 diabetes will develop kidney disease, according to researchers. Kidney disease from diabetes is the most common cause of chronic renal failure leading to ...Smokers more likely to experience impotence, Wake Forest study shows
... erection or to complete intercourse, he said, and affects an estimated 30 million Americans. "These data are the first to quantify a 26-fold increase in erectile dysfunction among primary care men with hypertension who also currently smoke, a rate that is also twice that of former smokers," said Spangle......and increasing levels of obesity. "Type 2 diabetes affects 1 million people in the UK, with a similar number who have diabetes but don't yet know it. The complications of Type 2 diabetes and hypertension are potentially life threatening and have a huge impact on these patients' quality of life. We welcome ...Study shows infliximab can maintain long-term remissions in Crohns disease
...'s disease, a chronic inflammatory bowel disorder, affects approximately 500,000 Americans, typically beginning in late childhood or early adulthood. The disease causes inflammation of the gastrointestinal tract. It can result in diarrhea, fever, abdominal pain and weight loss. In up to 30 percent of pati...... Asthma is a chronic lung disease that currently affects more than 15 million Americans, approximately 40 percent of whom have moderate persistent asthma. It is currently estimated to cost the U.S. economy $12.3 billion a year in health care costs and lost productivity. Asthma is due to an inflammato......ers. With a disease such as type 2 diabetes, which affects numerous organs throughout the body, it is difficu...ins within the pathway. Diabetes is a disease that affects multiple organs, so it helps to look at the disease in terms of an entire organism, said Birnbaum. I...Microbes and the dust they ride in on pose potential health risks
...illosis is a mold-like infection of the lungs that affects animals and birds. Coccidioidomycosis presents a more direct hazard to humans and has affected inhabitants of the arid southwestern U.S. Coccidioidomycosis is caused by Coccidioides immitis, which causes pulmonary illnesses in humans that range fr...