Alcohol researchers confirm molecular culprit of alcohol-induced liver damage
...n known to exert aprotective effect on liver cells against alcohol attack. Supported by a grant from the NIAAA, the researchers combined gene knockouttechnology and the enteral feeding techniques originally developed by Tsukamotoand French to allow continuous tube infusion of a high-fat diet with alcoholinto...Tamoxifen found to increase risk of endometrial cancer
...vival. It is also under study as apreventive agent against breast cancer in women at high risk for the disease.However, this study indicates the same drug increases the risk of endometrialcancer, the most frequent gynecologic cancer in women. "Because tamoxifen is a critical therapeutic option for breast can...Estrogen may play role in prevention of cataracts
...idemiological studiesthat estrogens are protective against cataracts," said Dr. Bigsby. Seventy-five ...mone replacement therapywill also prove protective against cataracts," Dr. Bigsby said....NIAID spearheads collaborative network for clinical research on immune tolerance
...her immune cells to function normally as defenders against invadingbacteria, viruses and cancer cells. Similar clinical trials are planned for patients receiving transplanted humanislets to treat juvenile or type 1 diabetes, a disease caused by the autoimmunedestruction of insulin-producing cells in the panc......sults comparing the two speech enhancement schemes against no pre-processingfor a group of elderly hearing-impaired subjects. (2pSC1) -- Unique Properties of African Music . African music has many distinctivecharacteristics that go beyond the obvious. David Avorgbedor and James Pyne( Pyne.1@osu.edu ) o......ogist with Lau's group. They study immune defenses against viral infection. In two previous papers published in PNAS, they have described a dual role inantiviral control and apoptosis regulation for an enzyme in normal cells calledPKR, a protein kinase activated by RNA. The PKR gene produces this enzyme whe...... with farm animalscould provide lasting protection against allergic illnesses, according to theauthors of a broad-ranging study conducted in Austria on 2283 children agedbetween 8 and 10. The study, which was presented on Monday at the meeting of theEuropean Respiratory Society (ERS) in Madrid, was a joint e...Global prevention, funding and accountability debated in fight against HIV/AIDS
...nce delegates that "criticaladjuncts [to the fight against AIDS must] include health education ofpopulations,...to some of the dauntingpolicy changes in the fight against AIDS, like treatment access in thedeveloping world. Industry investment can be encouraged by contin......opausal women an excellent new weapon in the fight against osteoporosis. In a placebo-controlled study of 2,458 post-menopausal women with osteoporosis,researchers found that after three years of treatment with the drug, calledrisedronate, the incidence of new fractures of the spine (vertebral) was reducedby...Discarded thymus tissue provides life for infants with DiGeorge Syndrome
... of aninfection, work together to protect a person against viruses, bacteria and otherpathogens. Without T cells, an infection that would have little impact on ahealthy person can be deadly, Markert said. Markert first tried the technique in 1993 when a Tennessee familycalled, hoping for help for the...Changing approaches to treating gum disease
...s metronidazole or doxycycline,which are effective against anaerobic bacteria. Because these systemic drugs, taken orally in the form of pills and tablets,travel throughout the body, they should be used for no more than one or twoweeks at a time, to reduce the chance of side effects or the development ofan...Racial disparity in lung cancer treatment must be overcome, UCSF specialists assert
...exists, but "we must strive to remove any barrier" against blacks. The co-authors note that some of the disparity in lung cancer survival amongblacks and among whites can be explained through smoking prevalence, how thebody metabolizes and excretes carcinogenic and mutagenic agents in tobaccosmoke, socioecon...New DNA chip method could improve cancer diagnosis
...n they cross-checked the diagnosesmade by the chip against known differences in the two types of leukemia, theyfound that the chip method could automatically discover the distinction betweenAML and ALL without previous knowledge of these classes. "These results demonstrate the feasibility of cancer diagnosi......he smoking population. "Given societal pressures against smoking, the majority of current smokers areeither in the process of quitting or interested in stopping, but many find itdifficult to quit and are treatment resistant," said Marina Picciotto, assistantprofessor of psychiatry and pharmacology at Yale....A new ion channel involved in cell proliferation: evidence for its oncogenic potential
...ood-brain barrier. This means that a drug designed against EAGwould not affect the normal function of cells, but only those growing in thetumor....New tests for blood clots, lung cancer use NIDCR patented technology
... and therapeutic trials using this Theratideä against melanoma and breastcancer are under development. The chemistry that facilitated the development of the new imaging tests is thebrainchild of Dr. Robey, Ray Fields, his assistant at the time, and formerVisiting Associate, Dr. Wolfgang Lindner. In 199...Duke team seeks novel vaccine strategy for HIV
...sible thesewomen have become "naturally" immunized against future HIV infections.A research team led by Duke ...ecreted into mucosal secretions toprotect the body against bacteria and viruses that attack the body mucosaltissues. "These women were probably exposed...Hopkins gene therapy trial is first to activate entire human immune system against prostate cancer
...an genetherapy to activate the human immune system against metastatic prostate cancer. The achievement, belie...bloodstream. Patients' B-cellsproduced antibodies against prostate cells, and their T-cells directly attackedthe tumor, the researchers report. Once re-educa......rged college freshmen to consider being vaccinated against meningococcal meningitis. Moshe Arditi, M.D., the ...bacterium: A, B, C, Y, and W. The vaccine protects against four of the five. "The college campus outbreaks have mostly been caused by group C and the vaccine i...Material that made car bumpers shine finds a role in manufacture of drugs, dyes
...ilines. "You can't just bang two solids up against each other and have themreact," says Miller, whose research project was supported by Eastman Kodak Co."You need a catalyst that can migrate from one material to the other." Traditionally scientists produce anilines by starting with powderycomp...