NEJM breast cancer study shows increased disease - free survival
...t concept of five years monotherapy with endocrine agents after surgical treatment of primary breast cancer. It shows that patients switched to AROMASIN experienced statistically significant clinical benefit and longer disease-free survival." The independent group monitoring the IES study recommended relea...Poor diet and physical inactivity may soon overtake tobacco as leading cause of death in U.S.
...ent). Other actual causes of death were microbial agents (i.e., influenza and pneumonia, 75,000), toxic agents (exposure to pollutants, asbestos, etc., 55,000), motor vehicle crashes (43,000), incidents involvin...Multi-center trial compares three medications in patients with heart failure
...tion about the relative effectiveness of these two agents and a combined analysis of the WARCEF and WATCH studies is planned, according to Massie. The WATCH study enrolled 1587 patients from 132 centers in the United States, Canada, and the United Kingdom. Enrollment began in October 1999 with the goal of r...Why don't heart patients take their medicine? Study finds forgetfulness at the top of the list
...ld showing how well these drugs work as preventive agents don't mean anything if patients aren't taking them." Eagle notes a recent study by U-M researchers which was published in the journal Circulation. It found that acute coronary syndrome patients who took one drug from all four of the "Fab Four" catego...Community hospitals do not transfer high-risk heart patients for aggressive therapy
...options for such patients" Roe said. Specifically, agents such platelet glycoprotein IIb/IIIa inhibitors were used in only 19.2 percent of the non-transferred patients, compared to 46.4 percent for those transferred. While the current analysis did not follow patients after they were transferred, the in-...State-required continuing medical education does not affect heart attack care
...in and beta blockers, these "branded" thrombolytic agents had little competition as agents for quickly reopening clogged arteries, they said. Since regulations vary from state to state ...Study looks at cost of high blood pressure therapy
...used. "However, the selection of antihypertensive agents by health providers is based on many factors. Price should be one of those factors, but, for most patients, the type of drug selected is not as important as getting the blood pressure lowered to the right level." Jones added that there is scientific...New breast pap smear detects early cellular changes; May prevent onset of breast cancer
...t cancers arise, and we don't know how the various agents we give to patients actually repair what is malfun... or a COX 2 inhibitor to determine if one of these agents can eradicate the abnormal cells. "RAR beta gives us a potential marker to monitor if the preventive...Harmless virus associated with longer life for some HIV-positive men
..., tuberculosis, malaria and illness from potential agents of bioterrorism. NIAID also supports research on transplantation and immune-related illnesses, including autoimmune disorders, asthma and allergies....Northwestern Memorial researchers study role of botanicals in management of menopausal symptoms
...s isoflavones, which are being studied as possible agents to fight cancer. A few studies have also suggested that isoflavones may help reduce hot flashes. ...Targeted antiviral prophylaxis of flu case contacts could successfully contain pandemic influenza
...housands of deaths could be prevented if antiviral agents were given to the close contacts of those with sus...sistance developing from prophylactic use of these agents has been shown to be much lower than for therapeutic use. The Emory scientists emphasize that the p...Scientists find HIV-blocking protein in monkeys
..., tuberculosis, malaria and illness from potential agents of bioterrorism. NIAID also supports research on transplantation and immune-related illnesses, including autoimmune disorders, asthma and allergies....Antibiotic provides promise in treatment of spinal cord injuries
...author of the study, notes that other experimental agents can prevent later-stage tissue loss, but must be given immediately after or even before SCI to be effective. "The field has badly needed to develop a drug that could be used in a practical manner," said Teng. According to the National Spinal Cord I...Insulin decreases inflammation, aids clot-busting drugs in heart attack patients, UB study shows
...ing insulin at low doses along with antithrombotic agents reduces the amount of increase in inflammation and rapidly suppresses the increase of factors than interfere with clot-dissolving medication," said Dandona. "We think that these effects, along with insulin's known capacity to dilate blood vessels and...Sepsis drug also protects brain cells
...is opens the door to a new class of anti-apoptotic agents based on blood factors that act directly on neurons" says Zlokovic, who is professor of Neurosurgery. "Regardless of the cause of neuronal apoptosis, neurons are able to survive in the presence of APC." In a paper last year in Nature Medicine , ...Cancer cells can compress blood vessels, block entry of drugs
...ed and abnormal and can actually block therapeutic agents from reaching malignant cells. In the Feb. 19 issue of Nature , researchers from Massachusetts General Hospital (MGH) describe how proliferating cancer cells compress both blood and lymphatic vessels within tumors. The findings suggest new strate...Targeting cell fusion as possible way to repair organs, deliver cancer vaccines
...tform that provides a way to choose and direct the agents of fusion by getting tumor cells to fuse with dendritic cells -- one cell type in the immune system. The result is biofusion that prompts the immune system to attack the tumor. "This is important because the exploitation of cell fusion, whether for ...At AAAS: Biocomplexity panel on human-nature interactions
... modeling decisions,"the researchers said, "is how agents (i.e., simulated households)learn from past experience and adapt these experiences to futureland-use decisions." The $2.7 million, 5-year project began in2001. "Human Ecodynamics in the Hawaiian Ecosystem, 1200-200 YearsBefore the Present" presented...Hormone released by bone marrow cells may hasten recovery from brain injury
...row can be converted with growth factors and other agents into immature nerve cells -- both in the laboratory and following transplant into animals. Furthermore, rats suffering from stroke or other traumatic brain injury recover neurological function quicker following intravenous infusions of bone marrow ...Sandia-developed foam likely would stop SARS virus quickly, Sandia/Kansas State team shows
...a to decontaminate chemical and biological warfare agents are likely effective at killing the virus that cau...ork built on previous efficacy studies on chem-bio agents Sandia had performed for DOE, the military, and the U.S. Department of Homeland Security. "The proto...