Residual tumor cells are a barrier to targeted cancer therapeutics
...osh. "They find a back door and progress to a more aggressive state that becomes independent of that pathway." Chodosh concludes that the type of genetically engineered mouse models used in these MYC studies yield results that are very similar to what is observed in patients and that molecular therapies will li...Ethics of neuroimaging research to be focus of NIH/Stanford meeting
... her brain showed an unusual response to sexual or aggressive images? Illes also pointed out that undergraduate students sometimes operate the machines that acquire the images for this sort of research. "When a subject goes into the study, does he or she know it might not be a medical professional who looks at ...Cervical cancer treatment depends on patient age
...ases the likelihood that they'll be given the most aggressive treatments for their disease, according to a study...ment, elderly patients were likely to receive less aggressive treatment. Surgery was used to treat 16 percent of the elderly group, whereas 54 percent the younger...Special JAMA commentary on lessons learned from troubles with COX-2 inhibitors
...lar medical researchers has issued a call for less aggressive direct-to-consumer advertising and better safety a...ety profile cannot be tolerated in the future. An aggressive position going forward is necessary for not only ensuring the safety of prescription medicines, but ...Size of myocardial infarct measured using MRI
...ess damage, and bigger infarcts often require more aggressive drug therapy or, in the most severe cases, surgery to repair heart tissue or prevent further damage." The Hopkins team measured the size of an m.i. in 13 dogs using eight different methods for analyzing pictures taken by a standard MRI, ranging from ...Harlem Hospital Center, Columbia affiliate, recognized for efforts to fight glaucoma
...nt will enable Harlem Hospital Center to pursue an aggressive screening program. We are extremely grateful for this assistance from the Foundation." "I am pleased that the dedication of our Harlem Hospital faculty is being recognized in this way," said Stanley Chang, M.D., chair, Department of Ophthalmology, C...Silent risk of osteoporosis in men with prostate cancer
... showed that primary care physicians were the most aggressive at managing osteoporosis while cancer specialists were the least....Study suggests Akt3 protein is key to melanoma's resistance to chemotherapy
...atients to show that as melanoma cells become more aggressive and metastatic, the amount of active Akt3 protein in the cells increases. In non-cancerous cells, another protein called PTEN phosphatase and tensin homologue starts a chain reaction ensuring that malfunctioning and damaged cells are killed. But a...First US SARS vaccine trial opens at NIH
...d before it was brought under control in 2003 with aggressive conventional public health measures. Researchers at the Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), will conduct the trials. The experimental vaccine agains...Stem cell research: The new medicine of the future
...mercial and academic players. A model of early and aggressive regulation has encouraged important and ethically acceptable areas of stem-cell research, while criminalizing irresponsible and unethical endeavors. The Human Fertilization and Embryology Act of 1990 allows the generation and use of embryos for resea...Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
LOS ANGELES, CA (December 6, 2004) Despite aggressive treatment, glioblastoma multiforme (GBM) the most...y to slow progression of the disease. But despite aggressive treatment, the tumor recurs and patients usually die within a year's time. Because GBM is so aggr...Got heart disease? The answer may be in your fingertips
...s angiogram, or perhaps even to find who need more aggressive treatment to slow or stop the progression of cardiovascular disease. "In this group of patients with chest pain, the noninvasive test was very sensitive in identifying those with early heart disease," says Dr. Lerman. "The next step is to extend the ...Mayo Clinic researchers announce promising next generation treatments for multiple myeloma
... (VAD) chemotherapy, except for patients with less aggressive disease for whom dexamethasone alone may be adequate," says Dr. Rajkumar. In the second study, Mayo Clinic researchers showed that using a new "cousin" of thalidomide may be more effective and safer in treating newly diagnosed myeloma. This analog o...Study shows haploidentical natural killer cells may provide hope for some patients with AML
...ve lost most of their natural ability to fight the aggressive cancer cells. This study is the first to successfully demonstrate that half-matched donor (haploidentical) natural killer cells that are transfused into a patient with AML can survive and persist to actively attack and kill the deadly canc...Employment reduces chronic drug use, UH professors find
...include poor academic and career achievement, shy, aggressive and impulsive personality traits, exposure to substance abuse by family members, lack of positive recreational programming and exposure to weak law enforcement for the use of illicit substances. To establish a preventative model in population...Mayo Clinic discovers potential marker for aggressive kidney cancer
...olecule that lets doctors identify one of the most aggressive types of kidney cancer. Patients with renal cell c...t if a cancer makes B7-H1, that cancer may be more aggressive because B7-H1 knocks down the host's immune system, thereby permitting the tumor to grow without int...Hiding drugs in food in nursing homes is common
...reduced function in activities of daily living, or aggressive behaviour were more often subjected to covert administration. Patients in special care units also had a higher risk of being given drugs covertly. These patients were most often given sedatives, probably to control and sedate demented patients with d...Hopkins Institute for Global Tobacco Control receives elite recognition from PAHO/WHO
...ation and training in support of a progressive and aggressive policy development agenda. These activities play a critical role in building and maintaining strong tobacco control programs. The IGTC has been active in all of these areas throughout the world. It participated in the 1996 national smoking survey in ...NCI scientists create model that predicts follicular lymphoma survival
...ession is rapid, with the cancer transforming into aggressive lymphoma and leading to early death," explained principle investigator Louis M. Staudt, M.D., Ph.D., of NCI's Center for Cancer Research. "Understanding the molecular causes of such differences in survival could provide a more accurate method to det...Ovarian cancer does have early warning signs, Mayo Clinic and Olmsted Medical Center find
...to stage in a matter of months, making it far more aggressive than malignancies such as breast cancer. Ovarian cancer occurs in 1 out of 70 women. ...