Study finds HER2-positive breast cancer invades organs due to fatal chemical attraction
...on Cancer Center have solved the mystery of why an aggressive form of HER2-positive breast cancer travels readily to a few key organs - lungs, liver and bone -where it then establishes new tumors. They say this finding may lead to strategies to block that deadly spread. The study, published in the November issu...Combination treatment helps thyroid cancer patients live longer
.... Anaplastic thyroid carcinoma is a very rare but aggressive form of the disease, afflicting less than 5 percen...r diagnosis. However, a new study suggests that an aggressive strategy combining surgery, chemotherapy and accelerated radiation therapy can improve survival for ...Malnutrition in early years leads to low IQ and later antisocial behavior, USC study finds
...he first few years of life leads to antisocial and aggressive behavior throughout childhood and late adolescence...e evident between malnourishment and antisocial or aggressive behavior, said Adrian Raine, a co-author of the study and holder of the Robert Grandford Wright Prof...Asymptomatic cardiovascular changes are powerful predictor of future heart disease
...s smoking, obesity and a sedentary lifestyle. More aggressive intervention at the time these changes are first detected could have a positive impact on cardiovascular disease-related illness and death. In a study presented today at the American Heart Association's Scientific Sessions 2004 in New Orleans, Lewis ...Lung cancer specialist calls for cash to beat 'Cinderella' disease
... 14 years investigating small cell lung cancer, an aggressive form of the disease, and is currently developing molecules which will trigger suicide in cancer cells. He says: "My work has also shown that the area of tissue around lung cancer cells produces survivor signals which stop chemotherapy and radioth...Heart surgery patients receive less aggressive discharge care
...scharge care given to angioplasty patients is more aggressive and is more consistent with national guidelines than is the discharge care given to the surgical patients," said Duke cardiologist Christopher Dyke, M.D, who presented the results of the Duke analysis Nov. 8, 2004, at the AHA's annual scientific sess...Radiotherapy + cetuximab significantly improve disease control and survival in head and neck cancer
...wth factor receptor (EGFR) that is associated with aggressive tumour growth and poor clinical outcome. Head and neck cancer is normally treated with high dose radiotherapy in combination with surgery. These phase III results were based on data from 424 patients (recruited from April 1999 - March 2002) with a me...New protein associated with aggressiveness in breast and ovarian cancer
...ells that "overexpress" the protein Rab25 are more aggressive and associated with poorer outcome. Thus, Rab25 could represent a novel therapeutic target or marker of tumor behavior, they say. The researchers matched tumor samples to outcomes in about 100 patients diagnosed with either breast or ovarian cancer a...Mothers have brains primed for care
...tressed by the change. They were more agitated and aggressive than the other groups. The monkeys separated from their birth mothers at one month of age experienced changes in eating and play behaviors, such as eating more and playing less. In another separate, but related study, Cameron and her colleagues then...Human spinal cord cells help rats with Lou Gehrig's disease
... The next step, he says, is to see whether a more aggressive treatment approach might further improve the outcome -- for example, combining low spinal cord implants as done in this study and grafts higher in the spinal cord to target the nerves that control breathing.......ted States, and we've got the opportunity to mount aggressive programs to prevent the unhealthy acculturation-related changes in diet and physical activity that have occurred with other immigrant groups," said Susan Foerster, chief of the Cancer Prevention and Nutrition Section of the California Department of H...Two novel agents work synergistically to treat lung cancer in animal experiment
...nt of IGF, a growth factor that is associated with aggressive lung cancer. Like other growth proteins, IGFs can bind to their receptors on cancer cells, and send signals inside the cell to enhance cell growth and division, inhibit the ability of the cell to destroy itself (cell death), induce angiogenesis (cons...Department of Energy announces new agreement with USC, national labs and private company
...ll allow USC and Doheny researchers to realize our aggressive goal of building a retinal prosthesis within the next five years that will allow patients mobility, as well as goals for the near future, which include reading and face recognition vision. We're really on our way now." ...'Energy blocker' kills big tumors in rats
...s difficult or impossible to treat, and many other aggressive cancers spread to the liver, so we need more treat...ne the compound's effects in an animal model of an aggressive non-liver cancer that spreads to the liver. ...Switch of a gene turns cancer cells healthy in mice, Stanford scientists find
...lated in the liver cells, and theanimals developed aggressive liver cancer within an average of 12 weeks. Returning these cancer-laden mice to the doxycycline diet again turned off the production of Myc protein and eliminated the cancer. After doing that, Felsher saw normal-appearing liver cells - a findi...Plastic surgeons honor 'Patients of Courage' overcoming difficult obstacles, inspiring others
...rt of her liver. Two years later, she developed an aggressive tumor on the scar from her surgery. Although surgeons were able to remove the tumor, Driskell had a severely deformed abdomen that required multiple reconstructive plastic surgeries. Despite a long battle with her insurance company, including several...Vioxx: An unequal partnership between safety and efficacy
...e new treatment. The Vioxx story is one of blindly aggressive marketing by Merck mixed with repeated episodes of complacency by drug regulators. We need clear statements from all parties in this sorry tale about the lessons to be learned. Without more vigilant drug regulation in the future, doctors will continu...Mechanism found that 'protects' aggressive melanoma from angiogenesis inhibitors
...l-forming endothelial cells, but not on insidious, aggressive melanoma cells that masquerade as endothelial-like cells by forming their own vascular networks, called "vasculogenic mimicry." Mary J. C. Hendrix, professor of pediatrics at Northwestern University Feinberg School of Medicine and president ...A glass of red wine a day may keep prostate cancer away
...ve effect appears to be strongest against the most aggressive forms of the disease, according to a new study led...saw about a 60 percent lower incidence of the more aggressive types of prostate cancer," said Stanford, senior author of the study. "The more clinically aggressiv...'Hedgehog' signal distinguishes lethal from localized prostate cancers
...ncer will stay put in the gland, and whose will be aggressive and spread -- a development that despite aggressive treatment is usually fatal. In the September 12 advance online edition of Nature, the Hopkins resear...