Drug shows promise in treating severe, often-lethal complication of stem cell transplants
...asthe kidneys and lungs. Under a research protocol allowing it to be used on an emergency basis, defibrotide was given to 88 transplant patients who had severe VOD and multi-system organ failure. The drug reversed VOD completely in 32 patients (36 percent), and 31 patients (35 percent) survived at least 100 d...9/11 one year on: Bridging the worlds divisions
...e emerging, with high sensitivity and specificity, allowing straightforward and relatively non-intrusive assessment to identify those at greatest risk of clinical progression to post-traumatic stress disorder. These approaches are designed for implementation 24 weeks post-impact, when brief-series cognitive b...Chemists show proteins behave differently inside cells than they do in water solutions
...in that they perform countless functions including allowing cells to grow and reproduce," Pielak said. "Almost everything we know about them comes from research done in test tubes in water solutions. But inside cells, where proteins work, there are no dilute solutions because the interior is crowded with prot...NIH supports ice slurry at Argonne
... chest compressions to circulate the cooled blood, allowing it to reach the brain and preserve brain cells. Data collected by the Argonne-university team has shown that the ice slurry cools the brain by 2 to 5 degrees Celsius very quickly. The process appears to keep the brain cool for an hour, which in a re......nd see how it performs under different conditions, allowing doctors to assess the risk of atherosclerotic disease due to disturbed flows, Barakat said. Details of the model are published in the August issue of the Journal of Biomechanical Engineering....Rensselaer research team sheds light on a good night's sleep for those with Alzheimer's
...ly, the body's temperature is high during the day, allowing people to remain alert and active. The temperature is low at night, which facilitates sleep. But those with Alzheimer's disease often wake up numerous times at night causing them to fall asleep more often during the day. The major result is nighttime...Equation rivals ultrasound in calculating birth weight
...lso predicts birth weight earlier than ultrasound, allowing doctors more flexibility when monitoring for fetal...on of excessively largefetuses early in pregnancy, allowing mother and physician more time to decide when and if induction of labor is the safest choice for mot...'Slice' scanner latest advance in early detection of heart disease
... beta blockers to slow down their heart rate, thus allowing the scanner to get better images of the heart. "Because multisclice spiral tomography coronary angiography is safer, requires no hospital admission and involves less patient discomfort, it will become a very suitable alternative in an increasing numb...Macrophages from human lymphoma patients cause mouse lymphoma in mice, UCSF study finds
...ages have HIV inserted near growth promoting genes allowing macrophages to become neoplastic. These cells begin to proliferate, another event that classical thinking about macrophages says is impossible. In addition, these proliferating macrophages, "pro macs", do what all macrophages do and produce factors....Doppler-guided fluid administration during surgery improves outcome
...oods much earlier. The researchers say that by not allowing fluid levels to drop below normal -- which is common during surgery -- the proper functioning of the intestines are maintained and recovery is improved. Typically, fluids such as blood, plasma or synthetic agents known as plasma expanders are adminis...Fred Hutchinson oversees two grants of nearly $8 million to develop blood test for breast cancer
... protocols and meeting minutes also can be posted, allowing investigators to jump quickly from discussion to data and references. The Department of Defense since 1992 has allocated funds for breast-cancer research. Its Congressionally directed medical-research programs also provide funding for prostate cancer...A little blue and purple helps body fend off deadly parasites
...a low-tech way to eliminate most of the parasites, allowing the body's immune system to fight the disease successfully. The dyes also removed from blood a number of disease-causing organisms, including viruses and bacteria." Brazilian physician Carlos Chagas discovered the disease in 1909. It is considered a ...Trauma surgeon seeks change in law that discourages counseling of problem drinkers
... documented that 42 states had adopted legislation allowing insurers to deny payment for treatment of alcohol related injuries. They discovered the statute was identically worded in 38 of those states, which led to the suspicion that the UPPL had a common source: a model law created by the NAIC and adopted by...Rutgers wins funds to create online index of moving brain images
...s of data that are transformed into moving images, allowing doctors to see how brain signals move across the brain. "Scientists would greatly benefit from accessing these images, to look for patterns that might provide clues about the differences between a diseased brain and a normal brain,"Kantor said. Cu...Analysis finds drug improves odds of complete stroke recovery
...a-analysis, results of clinical trials are pooled, allowing doctors to see trends that may not be apparent in smaller individual trials. The trials had used three oral doses of citicoline: 500, 1,000 or 2,000 milligrams (mg). Patient recovery rates at three months were assessed using three standard scales...University of Pittsburgh reports effects of multiple concussions in high school athletes
...g to Dr. Collins. Previous research has shown that allowing enough time for the brain to heal and recover before return-to-play is crucial in preventing more severe damage from possible further brain trauma during contact play. Generally, he said, most athletes who sustain an initial concussion can recover co...Keen ER identification could avert future strokes
...rt's two upper chambers quiver instead of beating, allowing blood to pool and clot instead of being pumped to the rest of the body. If a clot then leaves the heart and lodges in an artery in or leading to the brain, a stroke may result. However, regular treatment with blood-thinning agents particularly the...New drug linked to fewer deaths among kidney patients undergoing hemodialysis
... medications that bind dietary phosphorus, thereby allowing its excretion in the stool rather than its absorption by the body. Originally, aluminum hydroxide or aluminum containing compounds were used "because aluminum binds phosphorus very well," Finn said. "Unfortunately, some of the aluminum was absorbed ...Surgeons perform nation's first Zeus robotics system-assisted gastric bypass surgery
...omputer access to the hospital information system, allowing patient data to be accessed right in the operating room. The surgeon can upload X-rays and CT or MRI scans for reference, and even log onto the Internet to consult with another physician. Cedars-Sinai introduced robotics about 18 months ago in its f...Prenatal stem cell transplants may open door to organ transplants, treating genetic diseases
...of Philadelphia achieved immune tolerance in mice, allowing donor cells to multiply without toxic side effects...titive advantage for the transplanted donor cells, allowing them to multiply. "Performing the stem cell transplant prenatally relies on features of the fetal im...