Vitamin A compound may help protect younger women against breast and ovarian cancers
...ecause they have had a previous in situ cancer. In animal studies, fenretinide and tamoxifen -- the estrogen-receptor modulator which appears to dramatically block the development of estrogen-receptive tumors -- have been shown to have an enhanced effect against tumor formation. Addressing the problem of fe...... life, there is good reason to believe -- based on animal studies and in some human observations -- that sex...development. Dr. Hughes and his colleagues used an animal model to begin to determine whether this in utero phytoestrogen exposure might affect the organizati...New gene therapy shows promise in improving success rate of leg bypass surgeries
...t may have adapted the same way as in the previous animal studies. This gene therapy may have a significant impact on the success rate of all types of bypass procedures without much difficulty or expense," says Mann. Co-authors are Anthony Whittemore, M.D.; Magruder C. Donaldson, M.D.; Michael Belkin, M.D...Traditional Chinese diet helps ward off heart disease
...al "American diet" that contains larger amounts of animal fats -- a dietary shift that may be increasing their risk of heart disease and stroke. That's according to a study presented today at the American Heart Association Scientific Sessions. Villagers in Pan Yu, a town in Guangdong Province in southern...Brains of those in certain professions shown to have more synapses
... theinformation obtained through experience. "The animal literature strongly indicates that experience can drive the formation of newsynapses," said Black, a physician and professor of clinical psychiatry at the U. of I. at Chicago anda professor of neuroscience and psychology on the Urbana-Champaign campu...How long-term alcohol consumption can damage the immune system
..." said Rivier, "What we showed here is that, in an animal model, the body loses part of its ability to respond to additional stressors. Alcoholics may therefore become unable to activate their stress axis appropriately when they are faced with a challenge, and that can be damaging. In this study, we tried...Copper-lowering drug stabilizes advanced cancer in anti-angiogenesis trial
...angiogenesis, Brewer did work in the early 90's on animal cancer models treated with TM, with encouraging re...pment. Together with Brewer, she designed specific animal studies that allowed the team to test whether TM had the ability to prevent tumors from arising in a......vaccines, biotechnology, agricultural products and animal health care. ...Gene therapy reverses heart disease in mice
...rated that we could completely remove plaque in an animal or human just by altering the lipoprotein contents of the blood by a gene," Duverger says. The researchers bred a strain of mice that had very high cholesterol levels and deficient immune systems. One group of mice received the apoE gene therapy and...Estrogen shows potential as stroke treatment, UF animal studies show
...including Alzheimer's and Parkinson's diseases, as animal studies by Simpkins and others have demonstrated its ability to keep brain cells alive and healthy. Clinical trials are under way to determine its effectiveness in preventing or delaying the onset of Alzheimer's in people. Meanwhile, Simpkins has be...Common pathway found in early stages of addiction to alcohol and many drugs
...rlying systems of sensitization that would lead an animal or a human to want more of the substance, whether it is a drug or alcohol." In the research by Camarini and colleagues at the Federal University of Sao Paulo, Brazil, the scientists studied how mice responded to injections of ethanol alone and als...Novel approach may roust HIV from its hiding places
...r HIV ever can be eradicated from the body. In new animal studies, Vanderbilt University researchers led by Edna Choo, PhD, tested a compound called LY-335979 (LY) to see if it blocks the pumping action of P-glycoprotein, which is present in surface cells of blood vessels in the brain and testes. She presen......intensive tasks. Within six months to a year, each animal had achieved aconsistent level of performance, correctly completing 75 percent of all attempts. Yet, after receiving haloperidol at levels comparable to the typicalhuman dose, five monkeys demonstrated "significant memory impairment," makingerrors as...Pharmaceuticals and personal care products
...d to deal with the environmental fate of human and animal drugs, says researcher Ranga Velagaleti, formerly with ABC Laboratories in Columbia, Mo., now with BASF in Shreveport, La. The most common mechanisms for degradation and depletion of these drugs are hydrolysis, photolysis and biodegradation, he says....Nobel Laureate creates potent anticancer weapons
...natural form of the drug is found in a reef-living animal called Ecteinascidia turbinate, found in the West Indies. It was originally discovered approximately 12 years ago by a former colleague of Corey's from the University of Illinois, an avid diver. After discovering the agent in the finger-shaped append...Drug that curbs nicotine craving may do same for cocaine
...he urge to smoke cigarettes, has now been shown in animal studies to reduce their self-administration of cocaine. Rats that were trained to press a lever in order to get cocaine no longer pressed it with the same frequency after they were given mecamylamine, said Edward Levin, lead author of the study...Protease inhibitor could help prevent alzheimer's
...nly after continuing studies in the laboratory can animal and human testing begin. "If the ultimate inhibitor drug has low side effects, it should permit these people to live the rest of their lives normally," Tang said....Purdue 'stealth compounds' attack cancer cells
...Cancer Center. The researchers now plan to conduct animal studies using anti-cancer compounds developed at the center. Though pharmaceutical companies currently have several technologies available for carrying nucleotides into cells, those existing methods fall short in several ways, Borch says. "With c...Parenting, stress and your child's risk for alcoholism
...nt findings because these primates are the closest animal species to humans," she said. The study found that infant monkeys from both groups, peer-reared and mother-reared, were stressed by their separation from the group (as evidenced by cortisol concentrations), although the peer-reared monkeys more so. ...Biomedical informatics research group develops teaching/diagnostic software
...t to develop a diagnostic training module for food animal diseases using the technology. Bender began working on the project to improve the way veterinary students learn how to apply knowledge in a problem-solving environment. While first-year students enrolled in the DVM curriculum spend much of their time...