Duke eye researchers describe cascade of events that may lead to retinal degeneration
...se progresses so slowly in humans, researchers use animal models in which the progression is much quicker. In his series of experiments, Wong made use of a special line of transgenic pigs he and Robert Petters at North Carolina State University created. The team also used a well-studied mouse model of ret...FDA awards grant to metaphore pharmaceuticals to study septic shock in humans
...elates with the phenomenon they observed in recent animal studies. Findings of those studies, published ...reased levels of catecholamines. In the previous animal study, the researchers administered MetaPhores developmental antioxidant compound that mimics a natu...New discovery may revolutionize treatment for pain related to surgery, illness and injury
... and spinal cord, using nerves as a conduit, in an animal model. Axonal transport works like a "conveyor-belt" process, delivering pain-relieving medication to remote sensory endings in the tissues of the body. In axonal transport, the cell moves molecules from one end of the cell to the other, thus suppo...More evidence that soy may reduce breast cancer risk
... but it's a life-long process." He noted that some animal studies indicate that people need to start including soy in their diet from about the time of puberty in order to gain the cancer risk-reduction benefit. The amount of isoflavones present in the urine of the women in the study correlated well wit...Beer, in moderation, cuts risk of cataracts and heart disease
... Canada and the United States presented results of animal studies showing that beer, especially the darker a...an added benefit, in my opinion, at least from the animal model." Vinson also is presenting the results of several other studies at the meeting that show anti...Australian chemists present new research findings at Pacifichem 2000
...cs in unusual sources: cultured fungi derived from animal dung and insects. (ORGN 1343, 9 a.m., Monday, Dec. 18) More than 8,000 research papers will be presented during this year's International Chemical Congress, which is sponsored jointly by the ACS, the Chemical Society of Japan, the Canadian Society of...Mouse provides clues about chronic pain
...te and can lead to changes in how the human or the animal perceives external pain signals. The genetically altered mouse that overexpresses NR2B, consequently enhancing the activity of NMDA receptors, provided Zhuo and colleagues with a ready-made model for exploring NR2Bs role in the forebrain. The rese...Scientists find link between dopamine and obesity
...atisfaction circuits, the researchers suggest. "In animal studies conducted elsewhere, exercise has been found to increase dopamine release and to raise the number of dopamine receptors," Volkow says. This suggests that obese people might be able to boost their dopamine response through exercise instead of ...Altered mice provide model of rare childhood disease, NIH and Georgetown researchers find
...he National Academy of Sciences (PNAS). Having the animal model will enable scientists to study the underlying mechanisms of Jervell and Lange-Nielsen Syndrome, and ultimately come up with new strategies for alleviating the problems it causes, said Steven Ebert, PhD, assistant professor in Georgetowns Depar...... The next steps are to test adenosine compounds in animal models of human diseases....Cincinnati chemist wins national award for medical contributions
...lp people." That is why he advocates appropriate animal research. "Animal-rights groups have stopped medical research that should be going on. I couldn't have done the work I did without using animals," he said. Clark received his undergraduate degree from Antioch College in 1941 and his Ph.D. from the ...Animal studies indicate new approach for treating end-stage skin and kidney cancers
...iation for Cancer Research 92nd Annual Meeting. In animal studies conducted by researchers at the Huntsman C...mutase (SOD), as a co-therapy with IL-2 in several animal models of advanced cancer. Previous studies have confirmed that the synthetic enzyme effectively rep...Stony Brook chemist wins national award for drug discoveries
...s, said Ojima. So far the approach is promising in animal tests, he added. A native of Japan, Ojima said his early interest in research was sparked by his father, an inorganic chemist. As for his particular field, he added, "I think just knowing cancer patients personally encouraged me to do something abo...Stimulating environment protects brain against damage from lead exposure
...ent." The researchers would like to continue the animal studies to test if there is a critical duration of exposure to an enriched environment that may protect against lead, both in terms of behavior and brain chemistry. Also, the researchers would like to find out if there is a critical age after which e...Methadone may cause potentially fatal arrhythmia, Georgetown researchers find
...hadone blocks a key potassium channel in human and animal cells, which, if the same thing occurred in a human heart, could lead to a potentially fatal arrhythmia. The teams findings have not yet been confirmed in humans, but their hypothesis about methadones role in causing arrhythmias came from anecdotal r......o PFOS, he said. Giesy collected more than 2,000 animal tissue samples, from the Pacific Rim to Antarctica, and analyzed more than 400 for PFOS. He found widespread distribution of the chemical and levels in mammals, fish and birds that he described as "surprisingly high." The findings indicate the reach ...Highest known catalytic rate for superoxide dismutation achieved
...n to exert protective anti-inflammatory effects in animal models. The compounds, part of a family being de...ed catalytic rate, exhibited protective effects in animal models of reperfusion injury and septic shock at dosage levels one hundred times less than those req...Investigational oral contraceptive reduces premenstrual and menstrual symptoms
...in addition to antiandrogenic properties, which in animal studies inhibited the effects of male sex hormones. Study Design In this six-month, open-label study, which was part of a 13-month multicenter evaluation of Yasmin as an oral contraceptive, 326 women aged 18 to 35 years were given Yasmin for 13 cyc......ocally active estrogen with no systemic effect [in animal studies]," said Richard Hochberg, Ph.D., the lead investigator in the study and a professor in Yale's Department of Obstetrics and Gynecology in New Haven, Conn. Although vaginal atrophy can be effectively treated with estrogen replacement therapy, t......a. Controlling insects also benefits human and animal health. Ten years ago, Heather Wren, received a lo...ison to enter the food chain, such as if a bird or animal eats the dead insect." Wren's compounds have been registered by the U.S. Environmental Protection...