New drug works well as sole epilepsy therapy for difficult-to-treat patients
...ight seizures a month despite treatment with other antiepileptic drugs," says Ahmad Beydoun, M.D., associate profes...re maintained on a constant dose of the one or two antiepileptic drugs they had been taking prior to enrollment. To qualify for advancement into the double-blind tre...People suffering from epilepsy continue to lack a good quality of life
... epilepsy have inadequate control of seizures with antiepileptic drugs (AEDs); resulting in substantial deleterious effects on individual health and quality of life and a heavy burden on society. These patients are considered refractory and are in need of another therapy besides medication to gain seizure control......nsive imaging equipment, or to cheap but effective antiepileptic drugs. Traditionally, THE LANCET has had a global outlook, and TLN plans to continue in this vein wherever possible. In this issue Gretchen Birbeck, who was awarded an International Fellowship by THE LANCET in 2001, describes her experiences as a wes...Reducing antiepileptics in VNS (TM) patients does not impair seizure control
...l 18, 2002 (Nasdaq: CYBX) Reducing the number of antiepileptic drugs (AEDs) used in combination with VNS (Vagus N... with epilepsy to reduce the number or dose of the antiepileptic medications they take. VNS Therapy with the Cyberonics NCP System was approved in 1997 for use as ...Vagus Nerve Stimulation Therapy (TM) more effective in epilepsy patients when used earlier
... of seizure onset or after trials of four or fewer antiepileptic drugs (AEDs). Many patients have had epilepsy fo... with epilepsy to reduce the number or dose of the antiepileptic medications they take. VNS Therapy with the Cyberonics NCP System was approved in 1997 for use as ...Hebrew University student developing drug to treat epilepsy, migraines, chronic pain
...Yagen, whose areas of expertise include developing antiepileptic and CNS drugs, spent the past four years working on developing an antiepileptic drug that would be more effective and not cause the side effects common to existing antiepileptic dr...Opioids, narcotic analgesics effective in treating post-herpetic neuralgia
... patch, oral tricyclic antidepressants (TCAs), and antiepileptic drugs. While TCAs are the most widely studied drug class, they fail to provide at least moderate pain relief in nearly half of PHN patients, and with considerable side effects. The role of opioids in treating chronic non-cancer pains such as PHN ha...New data confirm KEPPRAs place at the forefront of epilepsy management
...at long-term treatment with KEPPRA gives sustained antiepileptic effect, with a high retention rate and an adverse event profile similar to that seen in the randomised controlled previous trials. This is good news for physicians, who can confidently choose KEPPRA to treat their patients, without compromising thei...High-dose radiotherapy could reduce cognitive function for people with low-grade brain tumours
...airment, and that other factors-notably the use of antiepileptic drugs-may play a role in reducing cognitive functi...and treatment effects (neurosurgery, radiotherapy, antiepileptic drugs) on cognitive function and on the relative risk of cognitive disability. Patients with low-gr...Antiepileptic drug developed at Hebrew University to undergo phase three clinical trials
The new antiepileptic drug valrocemide, developed at the Hebrew Universi...'s population suffers from it, and annual sales of antiepileptic drugs in the U.S. amount to more than $2 billion per year. There are several existing drugs on the ...Two UC Davis studies show promising single-drug therapy for hard-to-control epilepsy
...s Medical Center have found that levetiracetam, an antiepileptic drug typically used in combination with other drug...d to levetiracetam monotherapy after failing prior antiepileptic medications, such as phenytoin sodium, carbamazepine, divalproex sodium, lamotrigine and topiramate....The NCOA and The Epilepsy Foundation launch initiative to educate about epilepsy in the elderly
...pulation. One recent study found one of the newer antiepileptic drugs was highly effective in preventing seizures without interacting with other medications for more than 70 percent of the elderly patients evaluated. Finding a treatment that controls seizures and provides few side effects is important to the qu...Anti-epilepsy drug, topiramate, effective at preventing migraine headaches
Among patients with migraine headache, the antiepileptic drug topiramate appears effective in preventing migraine attacks and for reducing the use of rescue medication for headaches, according to a study in the February 25 issue of The Journal of the American Medical Association (JAMA). "Migraine headach...American Academy of Neurology and American Epilepsy Society guidelines for treating of epilepsy
...eline for the treatment of epilepsy with these new antiepileptic drugs (AEDs). "These guidelines are designed to provide evidence-based assessments on the use of the new anti-epileptic drugs to clinicians," said Jacqueline French, M.D., professor of neurology at the University of Pennsylvania School of Medicine in...Emory researcher examines effects of antiepileptic drugs on pregnant women and their offspring
...ata show that babies of epileptic mothers who take antiepileptic drugs (AEDs) during pregnancy absorb the medicatio... risk of the general population, and we think some antiepileptic medications may be to blame," says Page Pennell, MD, associate professor of neurology, Emory Univers...Patients with uncontrolled epilepsy have low levels of fatty acids
...t develops in one brain region and is resistant to antiepileptic medication) when compared to a control group of 57...ink low DHA to seizures which cannot be managed by antiepileptic medications. Reasons for the reduced membrane levels are unclear at this time. Future studies are ne...American Academy of Neurology guidelines for treating of epilepsy
...ideline for the treatment of epilepsy with the new antiepileptic drugs (AEDs). "These guidelines are designed to provide evidence-based assessments on the use of the new anti-epileptic drugs to clinicians," said Jacqueline French, M.D., professor of neurology at the University of Pennsylvania and one of the author...Tip sheet for the October 26, 2004 Neurology
...tion from brand phenytoin to generic phenytoin, an antiepileptic drug. After the switch, the patients' seizures increased enough to require intervention. The study concluded that brand and generic phenytoin do not yield the same concentrations in some patients, and substitution should not be permitted without noti...Injury from epileptic seizures relatively rare, Mayo Clinic study find
...ding to the study's findings: 1) greater number of antiepileptic drugs used, 2) less independent living situation, 3) higher Rankin score (a measure of disability in which a score of 0 represents no disability and 5 represents total disability), 4) history of convulsive seizures or atonic seizures and 5) high seiz...Adults taking eplileptic medications more likely to be unemployed
...ather by whether or not they were taking long-term antiepileptic drug therapy," said lead researcher, Matti Sillanp...mission off medication while 14% were still taking antiepileptic drugs (AED). However, the study found that whether or not they were in remission, those patients s...