Tag: "antiretroviral" at medical news
T cells target HIV in a relationship on the rebound
After a break in antiretroviral
drug therapy in HIV-positive patients, the virus r...he virus. Scheduled interruption and resumption of antiretroviral
treatment of HIV-positive patients has generated hopes of reducing drug toxicities, costs, and total...
Study identifies predictors of HIV drug resistance in patients beginning triple therapy
... on the problem of resistance developing in triple antiretroviral
therapy," said Richard Harrigan, Ph.D., director o...DS is designed to hit the virus with three or more antiretroviral
drugs from two or more different classes at once in order to reduce the viral load (amount of virus ...
Potential cure for lymphoma in HIV patients
... study, all Patients were to receive highly active antiretroviral
therapy (HAART) to help reduce these opportunistic infections and improve immunodeficiency, however, only nine Patients were able to tolerate this treatment for the entire study due to side effects such as nausea and inflammation of the mouth lining....
New therapeutic vaccine for HIV/AIDS eliminates needles and excessive toxicity
..., about 8 times a year, rather than daily. Current antiretroviral
therapies used to treat HIV combine several medica...er than orally or through injection. Combined with antiretroviral
drugs, DermaVir has shown to be more effective than when used alone, and does not have overlapping r...
Jefferson virologists coax HIV out of hiding
... cocktail of anti-HIV drugs known as highly active antiretroviral
therapy (HAART), they hoped they had found a way to finally rid the body of the virus. But they were wrong. The virus instead goes into hiding, dormant and practically undetectable in the body and impervious to attack. While HAART manages to keep th...
Triple-drug therapy promising against African HIV subtype
regimens that are widely used in the United States...roup first received standard TB treatment, then an antiretroviral
combination that has been successfully used to treat HIV-1 subtype B infections in patients with act...
Physicians may need to dig deeper when treating HIV-related lymphomas
...cases occurring before the advent of highly active antiretroviral
therapy, or HAART, in 1996, as well as after the introduction of the successful anti-HIV therapy. They saw 117 SNC cases and 143 DLCL cases before HAART, and 18 SNC and 84 DLCL cases after HAART. Throughout the period, all lymphoma patients were trea...
Low platelet counts linked to decreased survival in HIV-infected women
...oosted back to normal through use of highly active antiretroviral
therapy, or HAART, especially therapy containing zidovudine, also called AZT. Researchers found that factors associated with increased risk of thrombocytopenia included HIV infection, low CD4+ lymphocyte counts, increasing viral load, and smoking. I...
American Thoracic Socety journal news tips for December 2004 (first issue)
...ough 15 of the 16 patients were taking hepatotoxic antiretroviral
therapies and 4 patients were co-infected with chronic hepatitis B and C, only 2 or 16 were believed to have abnormal hepatic function, which the investigators considered to be within the range of prior experience. The study is published in the firs...
Imatinib (Gleevec) has activity in AIDS-related Kaposi's sarcoma
... developed world since the advent of highly active antiretroviral
therapies (HAART), it remains a significant cause of morbidity and mortality for AIDS patients in the United States and a major cause of mortality in the third world, given the limited number of effective treatments for KS. Researchers examined th...
Is the '3 by 5' initiative the best approach to tackling the HIV pandemic?
...in poor and middle income countries on life-saving antiretroviral
drugs by the end of 2005. But is this the right strategy for rolling back the world's worst infectious disease pandemic? A provocative debate in this month's PLoS Medicine pitches Dr Jim Yong Kim, director of the WHO's Department of HIV/AIDS, ag...
World AIDS day: US women with HIV lack access to health care
...stimated 460,000 women and men who need lifesaving antiretroviral
drugs are not getting them, according to a recent report by the Institute of Medicine (IOM) of the National Academy of Sciences. "These figures are appalling," said Paul Volberding, MD, chairman of the HIV Medicine Association (HIVMA) Board of Direc...
Important priorities for prevention and treatment of HIV/AIDS
...l. The provision of contraception for women on antiretroviral
drugs is seen as a priority, especially in Africa,...ransmission of HIV, avoiding the potential risk of antiretroviral
drugs harming the fetus, and avoiding the high risk of maternal and infant morbidity and mortality. ...
African children with HIV would benefit from daily doses of cheap antibiotic
...ophylaxis irrespective of age and CD4 count. Since antiretroviral
treatment is being introduced more widely in Africa, many countries are considering how to provide care and such treatment to HIV-infected children as well as to adults. The results of this trial should provide an impetus to provide clinical care wit...
HHS awards $10.4 million to fight AIDS on three continents
...clinical trial to determine the best time to begin antiretroviral
treatment in people who are co-infected with HIV a...iland) group will compare immediate versus delayed antiretroviral
therapy for pediatric HIV patients in sites in Thailand and Cambodia. Perinatally acquired HIV infec...
Custom-built facial implants helpful for patients with HIV and facial wasting syndrome
CHICAGO Patients taking highly active antiretroviral
therapy (HAART) for the treatment of HIV/AIDS often lose fatty tissues in the face as a result of treatment, making them appear gaunt and emaciated. Silicone facial implants can help these patients achieve a healthier appearance and fuller face, acc...
HIV-1 protease inhibitors: Effective against malaria?
...earch builds on a previous study that demonstrated antiretroviral
agents can reduce the adhesion of P. falciparum-in...endothelial surfaces. The authors believe that the antiretroviral
protease inhibitors attack the malaria parasite in ways that current antimalarial treatments do not....
Longterm immune memory cells cells do not develop during chronic viral infections
...s. A recent study of HIV infection showed that if antiretroviral
therapy is initiated during the early phase of infection, HIV-specific CD8 T cells are maintained more efficiently. "Our research shows that prolonged exposure to antigen without any rest results in cells that are "addicted" to antigen and cannot pe...
Virco establishes comprehensive set of clinical cutoffs for the vircoTYPE HIV-1 resistance test
... threshold for optimal selection and evaluation of antiretroviral
regimens -- for the virco®TYPE HIV-1 resistanc...linical cutoffs are available for a wider range of antiretroviral
drugs than those offered by other HIV resistance tests. In her presentation today at the 44th Inters...
New tool reveals molecular signature of cancer and HIV
...the virus itself that make it resistant to certain antiretroviral
drugs. Results of analyses of the new test are published in the November issue of Nature Methods. "We designed LigAmp to improve how we look for extremely subtle variations in viral and cellular DNA," says Eshleman, an associate professor of patho...
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