Use of antivirals by HIV-infected persons reduced their ability to infect partners
...e introduction and widespread use of highly active antiretroviral therapy (HAART) for HIV-infected persons in San Fr...blic Health (SFDPH) and UCSF. "While we found that antiretroviral use alone may account for a 60 percent reduction in risk of HIV transmission, a concurrent increase ...Combination, order of anti-HIV drugs make a difference in first-time recipients
...designing treatment strategies for patients new to antiretroviral therapy, says a new study funded by the National I...ug treatment strategy for first-time recipients of antiretroviral drugs. The findings are reported in two papers published in the Dec. 11 issue of The New England Jou...One combination of AIDS drugs appears better for starting treatment
...ve been fortunate to have a variety of choices for antiretroviral therapy," says Gregory Robbins, MD, MPH, of the Ma...ombination drug therapy also called highly active antiretroviral therapy (HAART) made a huge difference in the treatment of HIV infection during the 1990s, changing...'Survival sex' and substance abuse may hinder HIV prevention efforts
...by both economic need and addiction. Highly active antiretroviral therapy (HAART) patients were more likely to have unprotected sex than those who did not receive the treatment, perhaps because HAART patients believed they would not transmit HIV to their partners. However, said Dr. McGowan, although HAART can help ...Population surveys - A new 'gold standard' for estimating true incidence of HIV/AIDS?
...es for prevention of mother-to-child transmission, antiretroviral treatment, and testing and counselling for HIV-1 is increasing, future HIV-1 estimates will have to be assessed from an even greater number of data sources, all with different drawbacks and biases."...Emory and CDC scientists explore why most breastfed infants of HIV-positive mothers resist infection
...in late pregnancy or to the newborn, together with antiretroviral prophylaxis, she explains. Some of these approaches will be tested soon in large international trials. Other scientists involved in the study included CDC scientists Salvatore Butera, PhD and Ann Duerr, MD, PhD, MPH and Laurent Belec, MD, PhD, of the...Annals of Internal Medicine, tip sheet, November 18, 2003
...o complied with the drug regimens of highly active antiretroviral therapy (HAART) had low death rates (Article, p. 810). Among patients who adhered to treatment, survival was similar regardless of the CD4 cell counts at initiation of therapy. Patients with CD4 cell counts of 200 and above who did not refill their d...Potential low-cost options for monitoring HIV-1-infected children in less-developed countries
...ised countries) is more expensive than the cost of antiretroviral drugs in some resource-poor settings. Lynne Mofens...ly inexpensive means to establish when to initiate antiretroviral therapy in children in settings where CD4 and RNA assays are not available. Total lymphocyte count r...Study shows promise for HIV-infected liver transplant recipients
...ombined-drug treatment, particularly highly active antiretroviral therapies (HAART) in the mid-1990s, immune system ...hotopic liver transplantation. All but two had had antiretroviral therapy preoperatively, and all but one were treated postoperatively. The results: After a mean fol...Study finds subtle brain damage in some HIV patients on drug therapy
...and function of brains of HIV-positive patients on antiretroviral therapy with those of healthy subjects. Although i...lax about AIDS now," Chao says. "You see people on antiretroviral medications and they seem fine. But the take-home message of our study is that antiviral medications...FDA approves new HIV protease inhibitor, Lexiva (TM)
... HIV infection in adults in combination with other antiretroviral medications. The following points should be consi...ed in clinical trials with both PI-experienced and antiretroviral therapy (ART)-nave HIV patients. Lexiva may be dosed three different ways: 1) two 700mg tablets tw...Substantial survival increase after highly active antiretroviral therapy for HIV-1 infection
...with HIV-1 since the introduction of highly active antiretroviral therapy (HAART) in 1997. However the study also shows a shift in risk profiles compared with earlier data-people over 45 years no longer appear to have reduced survival compared with younger people, and individuals who acquire HIV-1 infection from in...Doris Duke Charitable Foundation selects Emory HIV/AIDS research team for innovation award
... countries. "The standard of care for monitoring antiretroviral therapy in the U.S. is based on tracking CD4 T ce...o they can also conduct high-quality monitoring of antiretroviral therapy." "All of the ongoing efforts to make antiretroviral therapy available in developing countri...Antiretrovirals reduce mother-to-child HIV-1 transmission when started after childbirth
...i in this week's issue of THE LANCET highlight how antiretroviral therapy targeted at babies soon after childbirth (because their mothers' HIV diagnosis was made around the time of delivery) is still effective in preventing vertical HIV-1 transmission from mothers to their children. Zidovudine and nevirapine have b...Antiretroviral therapy after birth decreases mother-to-child HIV transmission
...erved in studies in South Africa and Uganda, where antiretroviral drugs were given to both mother and infant. The researchers also explain in their study that a regimen of nevirapine and zidovudine is easily given to babies orally immediately after birth a single dose of nevirapine followed by zidovudine twice a ...Pet scans could provide insight into HIV-1 progression
...t of lymph nodes as a future option in addition to antiretroviral therapy in the management of HIV/AIDS. Lymphocyte activation-associated with vaccination or infection-can be measured by PET. David Schwartz and Sujatha Iyengar from the Johns Hopkins University Bloomberg School of Hygiene and Public Health, USA, and...UCSF begins study testing antiviral drug tenofovir to prevent HIV infection
... by the National Institutes of Health to study the antiretroviral drug tenofovir as a potential pre-exposure prophylaxis in Cambodia among high-risk, HIV-uninfected women. The research will look at safety and effectiveness of the drug in preventing the acquisition of HIV. "With both a vaccine and a microbicide man...Pharmacokinetic data presented at ICAAC on investigational HIV protease inhibitor 433908 (908)
...ism that occur in many patients being treated with antiretroviral therapy. "These data suggest that ATO doses should not exceed 20 mg per day when co-administered with 908 or 908/r, but once approved, the prescribing information for 908 will provide the most up-to-date information on potential drug interactions,"...Interim analysis comparing TDF to EFV in combination with 3TC + ABC
...domized, open-label multicenter study includes 345 antiretroviral treatment-nave patients with HIV infection. A tot...blets and Oral Solution, in combination with other antiretroviral agents, are indicated for the treatment of HIV-1 infection. This indication is based on two control...Study assessing once daily Abacavir (ABC) in a once daily ART regimen
...udies supporting the efficacy of a once daily (QD) antiretroviral (ART) therapy regimen and the QD dosing of Ziagen ...) 600mg QD. The ABC QD dosing regimen provided an antiretroviral response over 48 weeks that was shown to be non-inferior to the approved ABC BID dosing regimen, acc...