Guidelines issued for metabolic complications related to HIV & antiretrovirals
...re occurring in association with HIV infection and antiretroviral therapy have been issued by an International AIDS ...ng as many as half of all HIV-infected patients on antiretroviral regimens. Concerns about complications are causing some patients to delay initiating therapy and ot...Perception of punishment undermines HIV treatment adherence
...inal illness. Patients treated with highly active antiretroviral therapy, or HAART, face strict dosing times and food restrictions. Also, HIV infection can carry a stigma that negatively affects patients' psychological well being. Steven A. Safren, Ph.D., of the Massachusetts General Hospital Department of Psychia...Researchers identify less expensive HIV progression test as effective as current tests in use
...e test could be used to determine when to initiate antiretroviral therapy in HIV-infected persons. And because it co...therapy and are used to determine when to initiate antiretroviral therapy. However, the current tests to monitor CD4 lymphocytes and HIV-1 RNA are expensive. The heat...Annals of Internal Medicine, tip sheet, October 15, 2002
...t, and affordable advance in assessing exposure to antiretroviral therapies over extended periods." * * * Latest Case Study in Patient Safety Series Examines Hospital-Acquired Infections That Led to an Elderly Man's Death (Academia and Clinic, p. 665.)...Study shows why some immune systems control HIV
...who have controlled HIV for up to 20 years without antiretroviral therapy. The researchers found no significant difference in the number of HIV-fighting CD8+ cells between nonprogressors and the others. Instead, the scientists found that the nonprogressors' cells were better able to divide and proliferate when call...Macrophages from human lymphoma patients cause mouse lymphoma in mice, UCSF study finds
...f HIV infection that remains unaffected by current antiretroviral therapies, McGrath said. New therapies targeting HIV-infected macrophages hold promise not only for fighting lymphoma, but also could assist in eliminating latent reservoirs of HIV. A phase I/II clinical trial testing one of these therapies (SL1104...New protease inhibitor held HIV at undetectable levels for four years
...atment in patients who had not previously received antiretroviral therapy. To date in the Kaletra study, none of th...tudy, 100 patients who had not previously received antiretroviral therapy were given one of three doses of Kaletra in addition to the nucleoside analogues stavudine a...Study sheds light on cause of an AIDS treatment side effect
...lular processes. HAART is a combination of potent antiretroviral drugs such as protease inhibitors and nucleoside-analogue reverse transcriptase inhibitors (NRTIs). Researchers have known for many years that NRTIs in HAART cocktail regimens can directly cause mitochondrial toxicity by inhibiting a mitochondrial e...American Thoracic Society journal news tips for August (first issue)
...nsive care unit (ICU) in this era of highly active antiretroviral therapy (HAART) has a markedly improved survival r...nts will develop resistance to currently available antiretroviral agents, and will suffer immunologic decline. As this trend continues, ICUs are likely to see an ups...UCLA AIDS Institute scientists show antiretroviral drugs can eradicate AIDS epidemic
... researchers have predicted that widespread use of antiretroviral (ARV) drugs can eventually stop the HIV epidemic in its tracks -- even in African nations where a high percentage of people are infected. The Lancet Infectious Diseases reports the findings in its August edition. "Our findings sharply contrast the gl...The Lancet Oncology (TLO) and the Lancet Infectious Diseases (TLID)
...he Lancet Infectious Diseases (TLID) Combination antiretroviral therapies are widely used for the treatment of HIV but it is unclear whether they will continue to be effective in the face of quickly evolved drug-resistant strains of HIV, and increased risky sexual behaviour in certain communities. In the August i...Timely antiretroviral therapy essential for best prognosis in people with HIV-1 infection
... highlight how timely treatment with highly-active antiretroviral therapy (HAART) can substantially improve the thre...e and North America. The patients had not received antiretroviral therapy previously and started HAART with a combination of at least three drugs. 870 patients develo...Long-term interruption of HIV treatment may be safe in certain patients
... at least six months while receiving highly active antiretroviral therapy (HAART) interrupted treatment for an average of nine months. None of the patients had HIV-related infections or illnesses during the interruption. All of the patients had increases in virus levels and drops in infection-fighting CD4 cells....MTCT-Plus makes HIV treatment a reality for poor countries
...of 12 grants for HIV care and treatment--including antiretroviral therapy--for infected mothers, children, and other...will receive a variety of other support, including antiretroviral drugs, drugs for complications of AIDS, training and other technical assistance, and a commitment to...Eficiency, feasibility of antiretroviral therapy in Africa demonstrated in IRD-coordinated surveys
... in Sub-Saharan Africa. It is vital therefore that antiretroviral treatments, available and effective in industriali...voiced which hold back development and adoption of antiretroviral therapies in developing countries: uncertainty surrounding their biomedical efficacy, given the div...Treatment guidelines for HIV infection announced by international panel of AIDS experts
... recommendations around the four central issues in antiretroviral drug therapy: when to start therapy; what to star...al load remains an important marker of response to antiretroviral therapy. Newer formulations of drugs and the availability/approval of new drugs have resulted in eff...Tipsheet on XIV International AIDS Conference
...and how drugs are combined matters Highly active antiretroviral therapy (HAART) uses combinations of potent anti-H...est benefits for people who were not previously on antiretroviral drugs is poorly understood, as is the optimal order in which different regimens should be used. NIAI...Better control of liver enzymes saves lives of HIV patients, says University Of Pittsburgh
...emely high ALT and AST levels is to stop or change antiretroviral medications and to counsel patients to stop drinking alcohol. Mild to moderate elevations (0.5 up to 2 times the normal level) currently are not treated. The Pittsburgh-led study was an analysis of data on more than 5,700 participants from two obser...Drug combinations reduce HIV levels in untreated patients
...ing of the study. Patients who had previously used antiretroviral treatments for more than two weeks were excluded f...e reverse transcriptase inhibitor" class (NRTI) of antiretroviral treatments. The NRTI class of drugs inhibits the reverse transcriptase enzyme that the virus needs t...Exposure to hepatitis C has no effect on antiretroviral treatment outcomes in HIV patients
...imilar clinical outcome measures when treated with antiretroviral drug regimens compared to seronegative patients. T...reconstitution following exposure to highly active antiretroviral therapy (HAART). A notable difference between patients with both HIV infection and hepatitis C serop...