HHS awards $10.4 million to fight AIDS on three continents
...ect will evaluate the effect of daily doses of the antiviral drug acyclovir on levels of HIV shed in genital secretions of men and women who are HIV-positive and who also have active HSV-2 lesions. This will help clinicians better understand how active genital herpes infection influences HIV infectivity. HI...Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
...ch that kills cancer cells, in the presence of the antiviral drug, gancyclovir. In laboratory studies, this type of gene therapy has proved almost 100 percent effective. But in clinical trials, it has had limited effectiveness, suggesting that the virus is not able to deliver the suicide gene effectively int...NIH action plan charts future challenges for liver disease research
...hepatitis C. The currently recommended regimen of antiviral therapy results in long-term viral eradication in only 50-60 percent of patients; therefore, improved therapies are needed to benefit more patients with hepatitis C. Developing noninvasive ways to measure liver fibrosis. Currently, liver biopsy i...Study finds herpes virus in 98% of healthy participants
...aid Dr. Kaufman, who developed the first effective antiviral drug for herpes infections of the eye. In additio...ay be a simple, cost-effective way to evaluate new antiviral drugs....New therapeutic vaccine for HIV/AIDS eliminates needles and excessive toxicity
...e immune control is not permanent, data shows that antiviral activity of immune responses induced by DermaVir are significantly longer than that of existing antiviral drugs. It is suggested that DermaVir would only need to be re-administered periodically, about 8 ti...No advantage of combination drug therapy for chronic hepatitis B Infection
...ion treatment with pegylated interferon -2 and the antiviral agent lamivudine was more efficacious in treating chronic hepatitis B infection than pegylated interferon -2 therapy alone. Around 300 patients from 42 centres in 15 countries who had chronic hepatitis B were assigned combination therapy or monother...Potential cure for lymphoma in HIV patients
... significant because, despite the use of effective antiviral drugs such as HAART, lymphoma is still a major cause of suffering and death in HIV-infected individuals. It's important to know that stem cell transplant is an available and highly successful treatment option for these Patients," said Amrita Krishnan...Depression caused by common treatment for hepatitis C may affect outcome
... long been recognized as impediments to successful antiviral therapy. In the past we primarily worried that depression interfered with quality of life, or would cause patients to stop taking the medicine. These new data suggest that even if patients stay on treatment, they are less likely to have a good outc...New way to block pox shows promise in lab study
...l--an approach that might eliminate the problem of antiviral drug resistance, report researchers supported by t...says NIAID Director Anthony S. Fauci, M.D. Current antiviral drugs target the virus itself. "In contrast, our approach short-circuits a cellular chemical pathway...Hepatitis B viral load, genotype affect liver cancer risk, study finds
...ortant markers for defining high-risk patients for antiviral treatment among HBV carriers." In an editorial, James J. Goedert, M.D., of the National Cancer Institute, describes the significance of this new research in the path toward eliminating HBV infection and HBV-associated HCC, particularly in Asia where ...Scientists replicate hepatitis C virus in laboratory
...le and biology of this virus and to test potential antiviral compounds, which may lead to new therapies for the liver disease that results from infection with HCV. Scientists at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), one of the National Institutes of Health (NIH), conduc...American Thoracic Society Journal news tips for March 2005 (first issue)
... Workshop report noted: "An urgent need exists for antiviral drugs to prevent and treat SARS. During the first global outbreak, various interventions were used in management, including antivirals like ribavirin, interferon, and protease inhibitors, as well as host immunomodulary agents, particularly systemic ...St. John's wort amplifies effect of blood thinner Plavix
...s, including prescription antidepressants and some antiviral drugs, and to increase the skin's sensitivity to light. In most cases of interactions known to date, St. John's wort decreases the activity of a medication, rather than increasing it as appears to happen with clopidogrel. Says Eric Bates, M.D., a p...HIV-1 spread through six transmission lines in the UK
...he National Academy of Sciences, also suggest that antiviral therapy has not had a significant impact on the growth of the epidemic and that changes in sexual behaviour have been more effective in slowing the spread of the disease. The collaborative study led by University College London (UCL) scientists foun......The last three are longer-term: Secure vaccine and antiviral supplies. Enough vaccine and antivirals need to b...istribute them. IDSA is calling for a stockpile of antiviral drugs that is adequate to treat at least 50 percent of the U.S. population. Strengthen liability pro...