Controlling blood pressure early prevents heart disease in elderly
... a type of high blood pressure that is a result of atherosclerosis (stiff vessels or "hardening of the arteries"). Systolic hypertension is reflected in a blood pressure reading that has a high top (systolic) number and a normal low (diastolic) number. The SHEP trial lasted 4.5 years, after which participants who ha...Antioxidant gene mutation gives free radicals free reign
...his defect is a risk factor for the development of atherosclerosis in heart or brain vessels. Atherosclerosis leads to heart attacks and strokes, which are responsible for about 40 percent of all deaths in Western societies, says Juul. If the carriers of this mutation have a reduced antioxidative defense in the blo...Polycystic ovaries can lead to coronary artery calcification, says University of Pittsburgh
...r metabolic cardiovascular syndrome, and premature atherosclerosis in the coronary arteries," said Dr. Talbott. Coronary calcium deposits are an indicator of early, subclinical cardiovascular disease. In the study, researchers used electron beam computed tomography (EBCT) to scan coronary arteries of 41 women with ...Aspirin steps up as anti-inflammatory for arteries
...eful to prevent heart disease. Blood vessels with atherosclerosis become inflexible and inflamed. Researchers wanted to know if aspirin might protect against inflammation. Aspirin is widely used to prevent heart attacks and strokes, but it is assumed that its effects are solely attributable to its blood-thinning ...Grant will advance research of infection-fighting blood cells
...some human diseases such as heart attacks, stroke, atherosclerosis and arthritis," Dr. Skalnik adds. Other program investigators are Mary Dinauer, M.D., Ph.D., professor of pediatrics and medical and molecular genetics and director of the Wells Center; Wade Clapp, M.D., associate professor of pediatrics and microbi...Mayo Clinic study links gene to heart disease marker
...dentified inflammation as a major component of the atherosclerosis disease process, the accumulation of fatty plaques in arteries that can lead to heart attack or stroke. CRP, a protein marker of inflammation, has recently been recognized as a significant factor in understanding cardiovascular disease. IL-1, a prima...Angiogenic therapy offers promise for reducing claudication
...rmittent claudication of the calf muscle caused by atherosclerosis were randomly assigned bilateral intra-arterial infusions of placebo on days 1 and 30 (the control group); rFGF-2 (30 mg/kg) on day 1 and placebo on day 30 (single-dose group); or rFGF-2 (30 mg/kg) on days 1 and 30 (double-dose group). Data were ava...Insulin sensitizer has anti-inflammatory effect in diabetics
... with diabetes are at increased risk of developing atherosclerosis and heart disease. Dandona's lab has shown in rese...y to reduce inflammation is crucial for preventing atherosclerosis and cardiovascular disease, " said Dandona. "Previous data demonstrated rosiglitazone's effectivenes...PET/CT may identify 'vulnerable' aortic plaque
...owed by atherosclerosis. Yet, if identified early, atherosclerosis is reversible with medications and dietary and lifestyle changes. FDG is already a mainstay of nuclear medicine diagnosis because, when injected, it is "taken up" more rapidly by tissue with higher glucose metabolic activity. Not only is this of bene...American Thoracic Society news tips for June (second issue)
...ucing changes closely linked to the progression of atherosclerosis (narrowing of the arteries) in humans. This protein has also been shown to be higher in patients with uncomplicated hyperlipidemia (high concentrations of lipids in theblood), with or without atherosclerosis, and in those with untreated essential h...Estrogen may lower women's risk of heart disease by working as damper on inflammation
...elp to explain why women have a much lower risk of atherosclerosis (which begins as an inflammation of the blood vessel walls) than men until menopause," said Paresh Dandona, M.D., UB professor of medicine and head of the Division of Endocrinology in the UB School of Medicine and Biomedical Sciences, who is senior a...Genetic variant reduces immune response, yet protects against atherosclerosis
... represents a completely new mechanism involved in atherosclerosis and cardiovascular disease, and it provides a pote...4 inhibitors on humans at high-risk for developing atherosclerosis in the near future. Toll-like receptors, which were only discovered two years ago, appear to be the ...Drug to lower cholesterol also slows calcium build-up in arteries
... American Heart Association. In the development of atherosclerosis fatty plaques forming in artery walls can become calcified. Scientists speculate that studying calcium deposits inside patients' coronary arteries with computed tomography techniques, such as electron beam tomography (EBCT), can track the progressio...High levels of C-reactive protein indicate early heart disease
...nd coronary calcium, which indicates the extent of atherosclerosis in the coronary arteries. Atherosclerosis, or fat...ing scans, which may have blurred the link between atherosclerosis and CRP, says Wang. Future studies should clarify how best to combine the information from CRP test...Vitamin E is important for early prevention of cardiovascular disease in middle-aged women
...bifurcations, which are the sites where most early atherosclerosis begins. Women with the lowest intakes and plasma concentrations of vitamin E were more than twice as likely to have this type of plaque.4 Intakes and concentrations of vitamins A and C were not associated with carotid plaques. The Southern Italian...Can an aspirin a day keep atherosclerosis at bay?
...irin also lessens the inflammation associated with atherosclerosis and stabilizes athersclerotic plaque. Their findi... decade has seen a lot of research indicating that atherosclerosis is a chronic inflammatory disease," said Domenico Pratic, MD, assistant professor in Penn's Departme...Smokers infections increase risk of early atherosclerosis
...e more than three times as likely to develop early atherosclerosis than people without such infections. Early atherosclerosis was defined as new plaques in previously normal arteries. Infection also promoted artery disease in...Vitamin E fails to join heart-health regimen
...tamin E does not appear to slow the progression of atherosclerosis in healthy people, according to researchers from t...upported the idea that vitamin E protected against atherosclerosis by fighting oxidative damage, but results from the Vitamin E Atherosclerosis Prevention Study call t...Strong statin therapy reverses plaque build-up in arteries
...es is considered a good indicator of the amount of atherosclerosis throughout the body. The researchers found that m...howed a slight progression in the thickness of the atherosclerosis in their carotid arteries (from an average of .615 mm at baseline to an average of .640 mm thickness...Ethnic, gender differences in blood pressure also seen in youth
... thickening and hardening of the arteries known as atherosclerosis is connected with the level of endothelin-1 in the blood, according to the study....