Tag: "azathioprine" at medical news
Alcohol relapse adversely affects 10-year liver transplant survival
...y the end of the third month following transplant, azathioprine
was stopped and prednisone was progressively tapered over the first year. Follow-up periods ranged from 14 to 155 months, with a mean of 99.2 months. After their transplants, 14 patients resumed alcohol consumption. None of these patients had serious...
Donor age has no affect on long-term liver transplant survival
...ceiving treatment with maintenance steroids and/or azathioprine
tended not to develop severe fibrosis, even if lat... years," the authors state. They found maintenance azathioprine
to be an independent factor associated with survival advantage, overall and from 3 months. In additi...
First blood test to diagnose paralyzing, blinding disease
... therapy and immunosuppressive medications such as azathioprine
and corticosteroids can be effective in stopping the damage and restoring nerve function. It's not clear how many people have NMO, though it's generally regarded as rare in the United States. However, one Mayo Clinic physician in Rochester has seen ...
New data supports CellCept's position as a world leader in solid organ transplantation
... of post-transplant death) than those treated with azathioprine
(AZA) in the first year after heart transplantatio...I, et al. Long-term effects of the conversion from azathioprine
(AZA) to mycophenolate mofetil (MMF) in patients with chronic allograft dysfunction (CAD). Abstract ...
CellCept associated with reduced incidence of cancer, compared to AZA, following heart transplant
...egimens (defined as cyclosporine or tacrolimus and azathioprine
or CellCept), who underwent OHT between January 1, 1995, and December 31, 1997. Of these patients, 703 (18%) developed malignancy during the follow-up period through June 30, 2002. The breakdown of malignancy was as follows: skin (47%), post-transpl...
CellCept's cardioprotective profile reinforced
...ss coronary artery disease than those treated with azathioprine
(AZA) in the first year after heart transplantatio...domly assigned to receive CellCept (3000mg/day) or azathioprine
(1.5-3.0 mg/kg/day), in addition to cyclosporine and corticosteroids. IVUS results, including an i...
Mycophenolate mofetil superior to azathioprine: Slows vascular disease progression after transplant
...hickening of the inner artery walls, compared with azathioprine
(AZA). Intimal thickening is becoming increasingly important as a surrogate marker for long-term outcomes after heart transplantation. The study used intravascular ultrasound (IVUS) to measure intimal thickening in heart transplant patients immediate...
Immunosuppressant everolimus significantly reduces life-threatening heart transplant complications
...of the disease, when compared to the regimen using azathioprine
(1 to 3 mg/kilogram of patient body weight/day). The study included a novel approach and analysis for defining the presence and severity of cardiac allograft vasculopathy: intravascular ultrasound (IVUS). This technique uses sound waves to visuali...
Type 1 diabetes safely arrested with short-term use of new drug
... with the immunosuppressive drugs cyclosporine and azathioprine
were shown to preserve remaining beta cell function in newly diagnosed patients. But because patients in these trials generally suffered serious side effects from the drugs, such as increased infection risk, kidney disease and certain types of cancer...
Making kidney transplants last longer: Large UM study finds newer drug is better
...y failure better than the conventionally used drug azathioprine
(AZA). The effect was not just due to MMF's ability to reduce acute rejection responses. In fact, the new results show the relative risk of chronic kidney failure is 27 percent lower with MMF. Both MMF and AZA are used in conjunction with two other c...
Transplant Pioneer Thomas E. Starzl Most Cited Researcher In Clinical Medicine Over Past 17 Years
... the early 1980s that the drugcocktail prednisone, azathioprine
and cyclosporine could control organ rejectionpractically transformed the field overnight, making it more feasible totransplant livers, kidneys and hearts. In 1989, he and his team announced theirdevelopment of an even more effective drug therapy to...