Zebrafish: Drug discovery of a different stripe holds promise in COX research
...while lessening the risk of stomach ulceration and bleeding associated with traditional NSAIDs. One issue of c...hrombocytes zebrafish platelets and prolonged the bleeding time, while a COX-2 inhibitor failed to exhibit these cardioprotective properties. The researchers ...Early promise of alternative hormone treatment for breast cancer
...oxifen with respect to endometrial cancer, vaginal bleeding and discharge, stroke, venous thromboembolic events, and hot flushes. Tamoxifen was significantly better tolerated than anastrozole with respect to musculoskeletal disorders and bone fractures. Michael Baum comments: "Evidence from this first analy...Early promise of alternative hormone treatment
...oxifen with respect to endometrial cancer, vaginal bleeding and discharge, stroke, venous thromboembolic events, and hot flushes. Tamoxifen was significantly better tolerated than anastrozole with respect to musculoskeletal disorders and bone fractures. Michael Baum comments: "Evidence from this first analy...Think youre healthy? Open wide and look inside
...why abnormalities in the mouth, such as swollen or bleeding gums and oral sores, should be taken seriously. "...ms." One of the most common reasons for swollen, bleeding gums is gingivitis, the mildest form of periodontal disease where gums become red, swell and bleed e...Low-cost reminder helps prevent infections for heart patients
...king antibiotics before procedures likely to cause bleeding such as dental cleaning can often prevent infection. "One problem is that not all physicians know an individual patient's risk for endocarditis. A second issue is that many do not advise their patients about the risk. We are looking at easily im...Simple reminder can help patients avoid dangerous infection
...explains. Medical and dental procedures that cause bleeding such as teeth cleaning are among the most common causes of the infection. By taking antibiotics, generally one hour prior to dental cleanings, the threat of developing endocarditis is greatly reduced in patients with abnormal heart valves and conge...New practice guidelines focus on neuroimaging of premature and low birth weight babies
...emmorrhages. If the CT findings do not demonstrate bleeding in the baby's brain, then an MRI should be performed when the infant is between 2 and 8 days of age to look for evidence of hypoxic-ischemic injury to the developing brain, since this is a major cause of cerebral palsy in term infants, said Ment. ...Health recommendations from study on aspirin and lung cancer are premature
.... Akhmedkhanov. Aspirin can cause gastrointestinal bleeding and raise the risk of other bleeding disorders, especially in those with a family history of bleeding disorders. The exact dose of aspiri...Heart experts call for urgent action to implement new findings on cholesterol-lowering treatment
... did not produce any excess risk of strokes due to bleeding or of cancers at any site. This contradicts the apparent adverse trends in some other studies of vitamin E and beta-carotene. * The MRC/BHF Heart Protection Study involved more than 20,000 volunteers aged 40-80 who were at high risk of coronary heart...High cholesterol elevates women's risk of stroke death
...of the remaining deaths involved strokes caused by bleeding in the brain. For the entire study population, cholesterol levels averaged about 225 milligrams per deciliter (mg/dL). Researchers divided the population into five groups according to total cholesterol levels. Average total cholesterol levels for ...American Heart Association updates heart attack, stroke prevention guidelines
...says Pearson. "Aspirin can cause gastrointestinal bleeding and may increase the risk of hemorrhagic stroke (bleeding into the brain). But if a person has a 10-year risk of heart disease that exceeds 10 percent, the benefits of aspirin therapy greatly outweigh the risks." Similarly, Pearson says studies hav...Drug combo curbs artery re-closing after some heart attacks
...f coumarin is a higher risk of bleeding. However, bleeding complications as defined by TIMI criteria occurred in only 5 percent (seven patients) of the combined group vs. 3 percent (four patients) in the aspirin-only group. The difference wasn't statistically significant. "Since this therapy is rarely availa...Immune system supressor drug found effective in treating precancerous blood disorder
...low blood counts or they end up having strokes and bleeding to death. Myelodysplastic syndromes have been particularly troublesome to treat, since the cause of the disorder is not well understood, he adds. Bone marrow is the factory that produces all blood cells. In some older adults, the bone marrow becomes...The majority of hand cuts don't need stitches
... more than 8 hours after the time of their injury; bleeding could not be stopped after 15 minutes of direct pressure; cuts were associated with neurovascular, tendon, or bone injury; the cut involved the nail bed; the injury was actually a puncture wound or a cut secondary to a bite wound. The study authors d...Colorectal cancer drug provides important option for patients with advanced disease
...nclude nausea, diarrhea, anemia, increased risk of bleeding or infection or allergic reaction, according to the FDA's announcement of oxaliplatin's approval. Rothenberg noted that the approval of oxaliplatin was another in a line of advances for colorectal cancer patients. "When I was in medical school...No justification for early laser treatment of uncomplicated childhood haemangiomas
...iomas can be complicated by ulceration, infection, bleeding and occlusion of vital structures. Lesions--especially on the face - may cause cosmetic disfigurement. A wait and see policy is often advised; however use of laser therapy (pulsed dye lasers [PDL]) has been introduced in recent years, although its ef...New anti-inflammatory drug clears Alzheimer's provoking protein from brains of mice
... of long-term NSAID users develop gastrointestinal bleeding and ulcers, and nearly 100,000 Americans a year are hospitalized as a result of adverse effects from NSAIDs. "NSAIDs that release nitric oxide appear to protect the gastrointestinal system from injury and work well in removing the major irritant in ...Immediate cholesterol drop after heart attack guards against stroke
...nstances of hemorrhagic stroke, which is caused by bleeding into the brain rather than by a blocked blood vess...because several studies found an increased risk of bleeding stroke in one group of men with naturally low cholesterol levels, Waters says. "An estimated 1 mill...Drug shows promise in treating severe, often-lethal complication of stem cell transplants
... heparin to treat VOD, but the drugs caused severe bleeding and were ineffective in patients with multi-system...irs blood vessel injury, did not cause any serious bleeding and side effects, such as hot flashes, were mild. Richardson and his colleagues currently are conduc...... an antidote would give surgeons more control over bleeding in patients during and after surgical procedures, said Bruce A. Sullenger, M.D., vice chair of surgery at Duke University Medical Center and senior author of the study. "While heparin's blood thinning activity can usually be controlled with an exist...