Diuretics And Beta-Blockers Are Best Drugs To Combat High Blood Pressure, Study Finds
...antihypertensive agents. A much larger traditional blinded and randomized trial, the Antihypertensive andLipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT), is alsoscheduled for completion in 2001. This study, funded by the National Heart,Lung, and Blood Institute and the Department of Veterans ......ndependent. As a matterof policy, CEC members are blinded to the treatment assigned to each patient." The study was supported by the Duke Clinical Research Institute. Joining Mahaffey in the study were, from Duke, Dr. Barbara Tardiff, Dr.Christopher Granger, Dr. Kerry Lee, Dr. Robert Harrington a......d observing the children during thetrial, who were blinded to the treatment regimen, preferred Adderallthree-to-one over Ritalin as a continuing treatment. Results of the study, led by William R. Pelham, Ph.D., professor ofpsychology in the University at Buffalo College of Arts and Sciences anddirec......ve percent of patients participated in anoptional, blinded study extension up to 20 months of treatment. Among 115 patients with viral loads less than 30,000 copies/mL, 81percent of the LEUKINE patients were able to remain on the same antiretroviralregimen and maintain baseline level of viral......ial, which is nearing completion, alsostarted as a blinded study but was modified to "open-label" status to providethe medication for all children in the study. Although the current studies are intended to prove or disprove the effectivenessof IVIG therapy in kidney transplant situations, the treatment also......seniors remain independent longer. In this blinded study, participants gave themselves injections ofsynthetic GHRH or a placebo (inactive substance) each evening for five months.Before and after treatment, subjects were tested at the UW Clinical ResearchCenter for hormone levels, body composition, ph...Study shows obsessive-compulsive disorder runs in families
...id institutional bias. Diagnosing researchers were blinded asto a patient's condition. The study opens the door to the next step, identifying the actual gene(s)involved, says Nestadt. OCD affects as high as 3 percent of the world's population. Although ittouches all ages, the period of greatest risk is from ...Brain scans of Gulf War veterans show brain damage
...battalion. Investigators performing the tests were blinded to group identities. The findings were replicated among a small sample of six Gulf War Army veterans living in Dallas who have been diagnosed with Gulf War Syndrome 2. "Finding the same level of brain cell abnormality in the veterans from a diffe......ing program an opportunity to conduct a completely blinded HIV surveillance survey in high-risk groups brought to the jail," said McFarland. The study, which began in June 1999, tested for HIV in residual blood samples drawn for syphilis testing. Researchers did not track the patients by name, but were able...ARICEPT better tolerated than Exelon in patients with mild to moderate Alzheimers disease
...ng was administered by independent raters who were blinded to study medication. Key study findings: Almost 4 times as many patients in the Exelon (rivastigmine tartrate)-treatment group reported nausea compared with the ARICEPT (donepezil hydrochloride)-treatment group (41.8% vs 10.7%). Thre...Early treatment of blinding eye disease in infants can prevent severe vision loss
...y can stem its progression, many infants are still blinded by the disease. Due to a lack of clinical criteria to predict which patients will ultimately develop severe vision loss from ROP, ophthalmologists were forced previously to defer treatment until it was clearly indicated. Unfortunately, as it turns ...Mayo Clinic study shows no adverse heart effect for sildenafil (Viagra)
...r pill. Both the patients and the researchers were blinded to when they were testing the drug and when they were using the placebo. "In these patients, sildenafil had no adverse effect on symptoms or how long the men were able to exercise," says Patricia Pellikka, M.D., a Mayo Clinic cardiologist and the le...Avoiding wishful thinking over new drugs more trials should be double-blinded say cancer experts
...e urged that doctors should, wherever possible, be blinded to which drug a patient is receiving in a trial when the endpoint involves subjective judgements by the investigators. They believe it would lessen the risk of wishful thinking an unconscious tendency by doctors to expect new drugs to perform better...Researchers determine best possible drug option for cardiac arrest
...and who had one of the two drugs administered in a blinded fashion by Toronto Emergency Medical System (EMS) paramedics. The study found that almost twice as many patients survived to be admitted to hospital when they received amiodarone compared to those who received the traditional treatment of lidocaine. ...Over a quarter of interval cancers could have been detected during screening
...n screenings (interval cancers). Although it was a blinded review (they did not know in advance whether the mammogram showed a tumour or not), the radiologists did know that about 50% of the cases were either cancers or subsequent interval cancers, and therefore that they would have to select a high number o...ARICEPT significantly improves cognition, daily living over Reminyl in Alzheimers patients
...nance and correspondence. Trained raters who were blinded to study medication and trial results administered testing, using the modified ADAS-cog and the MMSE to measure cognition. ADLs were assessed with the DAD scale, a 40-item scale developed to assess both instrumental and basic ADLs across the full sp...Mastiffs could aid treatment of retinitis pigmentosa
...Kelling and Brian J. Miller. "A 200-pound mastiff, blinded in the prime of its life by PRA, is a force to be reckoned with, especially in homes with stairs and other obstacles," Acland says. "But a blind mastiff's human companions usually can help their pet adjust to its disability. Humans who lose their v...Postmenopausal hormone therapy offers no protection against heart attacks
...Follow-up Study (HERS II). HERS was a randomized, blinded trial to determine the effects of estrogen plus progestin (compared with placebo) in older postmenopausal women with heart disease. In 1998 HERS scientists reported that, surprisingly, risk of heart attack increased in the hormone therapy group durin...Aspirin within two days of ischemic stroke reduces deaths
...udies in which patients were randomly selected and blinded (they didn't know what type of therapy they were receiving). They found evidence from the published trials that giving 160 325 mg of aspirin within 48 hours of stroke onset offers a "small but statistically significant" decrease in death rates an...Quick blood test for heart failure proves successful in multinational trial
...using only the results of the BNP test. They were blinded to the results of other tests. When they combined the results with other clinical markers--physical symptoms such as shortness of breath, swollen ankles, or findings from other lab tests--the accuracy rate climbed to 90 percent and above. By itsel...