Tag: "blinding" at medical news

Positive Results Of Pivotal Phase III Trial With ENBREL In Patients With Early, Active Rheumatoid Arthritis

...cebo once a week in pill form to ensureappropriate blinding of the trial. The most common events reported in this trial in patients receivingENBREL were mild to moderate injection site reactions that did not complicatetreatment. ENBREL was approved to treat moderately to severely active r...

ENBREL application for early, active rheumatoid arthritis filed with the U.S. Food and Drug Administration

...cebo once a week in pillform to ensure appropriate blinding of the trial. The two primary endpoints studied were the ability of ENBREL to: 1) Slow the progression of RA as measured by digitized x-rays to monitor changesin joints. 2) Reduce signs and symptoms of RA as measured by numeric ACR response criter...

A leading cause of blindness may be controlled by simple course of oral antibiotic

... Clark Foundation pledged $66 million to eliminate blinding trachoma. A key component is Pfizer's donation of Zithromax,(r) their trade name forazithromycin, which the World Health Organization (WHO) now recommends for thetreatment of trachoma," says Penny Hitchcock, D.V.M., chief of the sexuallytransmitted d...

Anti-HIV treatment improves immune system and fights sight-threatening eye infection

... of cytomegalovirus (CMV) retinitis, a potentially blinding AIDS-related eye complication. A paper detailing these findings is published in the November 3, 1999 issue of the Journal of the American Medical Association (JAMA). Researchers at the Federal government's National Institutes of Health (NIH) found t...

Early treatment of blinding eye disease in infants can prevent severe vision loss

...nt options for retinopathy of prematurity (ROP), a blinding disease that affects premature, low birthweight in..."This is a great step forward in research to treat blinding eye diseases," said NIH Director Elias Zerhouni, M.D. "The NIH will continue to look for new ways to...

Effective surgery fails to attract patients unless costs are low

... to undergo surgery to correct their trichiasis (a blinding disease common in some developing countries) have found that many people with the condition choose not to have the simple and relatively successful operation, and that the procedure's costs may be a barrier. The researchers found, however, that if th...

Cancer-causing drug safe and effective in treating eye disease

...hly effective treatment for uveitis, a potentially blinding inflammation of the uvea, the pigmented layers of ... uveitis, according to statistics on blindness and blinding diseases compiled by the University of Washington. Uveitis is estimated to cause 10 percent to 15 pe...

Avoiding wishful thinking over new drugs more trials should be double-blinded say cancer experts

...advanced breast cancer). According to Dr Fossati, blinding is uncommon in these types of clinical trials. In ...sh bias emerged from our analysis, we believe that blinding should be strongly recommended for any subjective endpoint assessment such as response, time to prog...

Mastiffs could aid treatment of retinitis pigmentosa

...c (non-genetic or environmental) factors cause the blinding disease to progress slowly in some individuals, more rapidly in others and not at all in the lucky few who evidently have the genetic mutation but do not appear to go blind? That information might help design treatments to halt, reverse or even prev...

USC ophthalmologists announce launch of permanent retinal implant study

...amaged retinal cells in people suffering from such blinding diseases as retinitis pigmentosa and macular degeneration, will one day be able to restore some degree of vision to these patients. The investigational device was originally conceived of by Mark Humayun, M.D., Ph.D., professor of ophthalmology at the...

Eye drops can delay onset of glaucoma

...se people may delay, or possibly even prevent, the blinding eye disease, glaucoma. The study, called the Ocular Hypertension Treatment Study (OHTS), examined 1,636 people between the ages of 40 and 80. All had elevated pressure in the eye ocular hypertension but did not have glaucoma. About half (817) were...

FINAL ALERT: RPB Science Writers Seminar in Eye Research to be held in Washington, DC Sept. 22-25

...osure glaucoma, an eminently treatable form of the blinding disease. Asian populations, for instance, are about five times more prone to PACG than people of European descent. But not all smaller-eyed people go on to develop the disease; in truth, only about one in ten do. A new theory explains why. If bor...

A quick-change artist: Tiny protein folds faster than any other

...least 1,000 times slower than it does, leaving its blinding speed "quite a mystery," Hagen said. There are two ways of probing how proteins attain their shape: experiments in the lab and computer simulations. UF researchers have done both with Trp-cage. Hagen's team, which included Roitberg and UF physic...

Self-management program proves beneficial for macular degeneration patients

...e who suffer from depression associated with their blinding condition, benefit significantly from a relatively simple six-week self-management program, according to a team of physicians and researchers from the University of California, San Diego (UCSD) Shiley Eye Center and School of Medicine. In this study,...

Trachoma leaves millions blind, costs $2.9 billon to global economy

...$2.9 billion in lost productivity to low vision or blinding trachoma. The results appear in the article "Estim...have been identified as having known or suspecting blinding trachoma since the last estimate of the global burden. To estimate the prevalence and number of cas...

Report cites risks associated with over-the-counter cosmetic contact lenses

...s, epithelial keratitis, infectious ulcers and the blinding Acanthamoeba organism. Although no cases have been documented, the report also suggests HIV transmission is a potential risk among those who exchange their contact lenses with others....

UK childhood blindness more common than previously thought

...ry to address the largely insurmountable burden of blinding eye disease in the industrialised world. Their development will require integration of ongoing clinical, epidemiological, and basic scientific research. The fruits of this labour will have an effect worldwide, since the trends in childhood visual dis...

New technology offers quicker recovery, better results after vision-saving glaucoma surgery

...surgical technique in their arsenal to arrest this blinding disease caused when there is too much pressure on the inside of the eye. UT Southwestern ophthalmologists are among a few in the Dallas area to use the recently approved Ex-PRESS Mini Glaucoma Shunt, a metal cylinder smaller than a grain of rice. It ...

First international conference on women and blindness

...se their vision as men and how to stem the tide of blinding diseases in women. Called "Improving Women's Eye H...mune diseases in women and the ocular, potentially blinding features of these conditions. She will also describe her research on an autoimmune disease called pr...

Early treatment of blinding eye disease in infants can prevent severe vision loss

... retinopathy of prematurity (ROP) is a potentially blinding disease that affects premature, low birth weight infants. ROP is the growth of abnormal blood vessels in the back of the eye. These vessels can leak fluid and blood and lead to scar tissue inside the eye, increasing the risk of retinal detachment and...

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(Date:6/19/2013)... For years, Alzheimer,s researchers have focused on two ... Alzheimer,s and may contribute to the disease: plaques made ... protein, called tau. , But for the first time, ... two proteins independently, but at the interaction of the ... tissue of post-mortem Alzheimer,s patients and in mouse brains ...
(Date:6/19/2013)... is many fold higher in persons over 65 years ... how best to treat these older cancer patients. Furthermore, ... trials, those elderly patients who are eventually included are ... patient population is not well represented in clinical trials. ... now starting a new phase 2 trial in precisely ...
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