Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
...ma multiforme (GBM) the most common and deadly of brain cancers usually claims the lives of its victims w... virus increased the number of immune cells in the brain and significantly slowed tumor growth, increasing the survival of laboratory rats in pre-clinical st...Sleep loss boosts appetite, may encourage weight gain
...rcent decrease in leptin, a hormone that tells the brain there is no need for more food, and a 28 percent i...oduced by fat cells, connotes satiety, telling the brain when we have eaten enough. Van Cauter's team measured circulating levels of leptin and ghrelin bef...Month of birth linked to risk of MS
...in D levels during pregnancy may have an impact on brain development. These findings support suggestions that environmental factors both before and immediately after birth may influence the development of the nervous or immune systems and therefore determine the risk for this disease in adult life, they co...NHLBI stops sickle cell anemia transfusion study
...flow velocity in one or more major arteries of the brain is linked with narrowing in key blood vessels supp... magnetic resonance imaging study of the patients' brain arteries showing no severe blockages. Upon entry, patients were randomly assigned to receive either...Two-fisted assault on dopamine transport system may be foundation of Parkinson's disease
...sporting various chemicals such as dopamine to the brain area that controls body movement. Normally the enzyme parkin would protect the neuron from rotenone's assault on microtubules, Feng said. "When microtubules are broken down by rotenone, the disassociated protein building bl...Replicating an eel's nerve circuitry may aid paralyzed people
...jury, many patients are unable to move because the brain is cut off from nerve control centers called centr... a device that could mimic the signals sent by the brain and coax these nerve centers into sending "walking" instructions to muscles in a patient's legs. "Th...Rolipram - a potential new treatment for Alzheimer disease
...ial and contextual learning both measurements of brain function. Rolipram's protective effect is due to its ability to modify gene expression, making brain synapses more resistant to the insult caused by the accumulation of Ab. The beneficial effect of rol...New stroke prevention therapy as effective as invasive surgery
...r is opened over the carotid lesion to protect the brain from any material spreading during the procedure, ...s in the neck that deliver blood and oxygen to the brain can restrict or interrupt blood flow to the brain. The result is stroke. Stroke is the country's th...Methylphenidate improves attention, behavior of children surviving leukemia, brain tumors
...f childhood acute lymphoblastic leukemia (ALL) and brain tumors (BTs), the two most common forms of childho... low dose. "The treatment of children with ALL and brain tumor shouldn't end after the cancer has been eradicated," said Wilburn E. Reddick, Ph.D., director ...Imaging tool may help physicians diagnose bipolar disorder
...ve diagnostic test for bipolar disorder, a serious brain illness characterized by an alternating pattern of...n., identified significant differences between the brain chemistries of people with and without bipolar disorder. "The psychiatric community clearly need...Iris Murdoch's last novel reveals first signs of Alzheimer's disease
...uding arithmetic, spelling, and word production. A brain scan performed in June 1997 showed profound shrinkage in the part of her brain associated with memory, the hippocampus - a finding typical of Alzheimer's disease. The diagnosis wa...Novel imaging technique shows abnormal brain anatomy in children with ADHD
...t hyperactivity disorder (ADHD) display anatomical brain abnormalities beyond chemical imbalance, according...SNA). Stimulant medications prescribed to balance brain chemistry appear to normalize some of these brain irregularities, a second study reported. "We foun...Antibiotic rifampicin shows promise for fighting Parkinson's disease in lab tests
...on of protein fibrils associated with the death of brain cells in people with Parkinson's disease. The drug...der resulting from the death of nerve cells in the brain that produce the neurotransmitter dopamine. Deposits called Lewy bodies, composed mostly of alpha-sy...Brain imaging with MRI could replace lie detector
...ir brains than when they tell the truth, and these brain changes can be measured by functional magnetic res...n the polygraph. "There may be unique areas in the brain involved in deception that can be measured with fMRI," said lead author Scott H. Faro, M.D. "We were...Brain remapping may be key to recovery from stroke
...uffering from paralysis due to stroke or traumatic brain injury may be able to reprogram their brains to im...onance imaging (fMRI) and a "cyberglove" to record brain changes during motor activities, researchers demonstrated that people can learn to remap, or redirec...Canadian researchers to develop 'smart drug' to repair psychiatric disorders
"Smart" drugs capable of targeting specific brain cells to control psychiatric disorders such as aut...w generation of medications that will work only on brain cells in areas that need to be repaired," says Wang. "This new type of drug will correct abnormal br...Testosterone deficiency found in one-third of diabetic men
...sterone, or of the hypothalamus, the region of the brain that controls the pituitary. "This starts a whole new story on the crucial complications of type 2 diabetes," said Paresh Dandona, M.D., senior author on the study and director of the Division of Endocrinology, Diabetes and Metabolism at the Univer...Humble Planaria worm offers ideal model for drug withdrawal research
...t despite this simplicity, the Planaria worm has a brain and spinal cord, both key to studying the effects of drug abuse and withdrawal. Furthermore, Planaria have the same types of neurotransmitter systems as humans and thus respond to dopamine, opioids, cocaine and cannabinoids. "Planaria offer a cl...Brains of people with autism recall letters of the alphabet in brain areas dealing with shapes
... remember letters of the alphabet in a part of the brain that ordinarily processes shapes, according to a s...results from a failure of the various parts of the brain to work together. In autism, the theory holds, these distinct brain areas tend to work independentl...FDA grants accelerated approval of TYSABRI, formerly antegren, for the treatment of MS
...cells from migrating from the bloodstream into the brain where they can cause inflammation and potentially damage nerve fibers and their insulation. "TYSABRI is a powerful and innovative therapy that offers new hope for hundreds of thousands of people living with MS," said James C. Mullen, chief executiv...