Can the standard course of radiation therapy following lumpectomy be shortened?
...e standard course of treatment for many women with breast cancer who have had breast-sparing surgery, called...er that leads them to choose mastectomy instead of breast conservation." In an effort to reduce the burden of treatment on women, Freedman an...Re-analysis of large trials shows greatest benefit of chemotherapy in ER-negative tumors
...that cancer research and treatment have focused on breast tumors that are estrogen receptor (ER)-positive, a...tics and Applied Mathematics, looked at decades of breast cancer clinical trial experience and found that "the benefit of chemotherapy advances over the last ...Celecoxib shows surprising activity against estrogen receptors
...elecoxib (Celebrex) in women at risk of developing breast cancer results in the reduction of estrogen receptor expression in breast cells, a research team at The University of Texas M. D. Anderson Cancer Center has found. The surpr...Breast cancer may be 'uniquely sensitive' to inhibitors of PI3K pathway
HOUSTON - Because up to 75 percent of breast cancer patients have an abnormality in a specific ...he phosphatidylinositol 3 kinase (PI3K) pathway to breast cancer development, says Gordon Mills, M.D., Ph.D., a professor and chair of the Department of Molec...New data sets survival benchmark for Pfizer's ELLENCE
...ponent of treatment of patients with node positive breast cancer," said William Gradishar, MD, Associate Pro...i-center clinical trial. Women with node-positive breast cancer were randomly assigned to receive either an adjuvant chemotherapy regimen containing six cycl...Molecular test predicts risk of breast cancer recurrence and who will benefit from chemotherapy
A new test can predict both the risk of breast cancer recurrence and may identify women who will ...nosed with estrogen-dependent, lymph-node negative breast cancer* every year are at low risk for recurrence and may not need to go through the discomfort and ...Jefferson scientists find way to see breast cancer activity from outside the body
...ter. The scientists would like to detect cancerous breast tumors as early as possible, particularly before t... called cyclin D1, is turned on in the majority of breast cancers, he explains. The genetic probe, which is a DNA derivative, carries an attached radioactive ...Novel p53 gene-based therapy boosts immune system and reduces tumor size
...ANTONIO - Use of a novel gene-based therapy before breast cancer surgery reduced tumor size by nearly 80 per...logy. About half of patients with locally advanced breast cancer have mutations in their p53 gene, which plays a critical role in suppressing cancer developme...Cell marker identifies patients who are more likely to respond to taxol
...monly used before or after surgery for stage I-III breast cancers, even though only a subset of women ultima...tely benefit from this treatment. Patients whose breast cancer cells have lost their ability to express a protein called "tau" are twice as likely to have a...New molecular classification of breast cancer predicts response to chemotherapy
Different molecular subtypes of breast cancer respond differently to chemotherapy, a rese.... The findings reinforce the emerging notion that breast cancer should be classified according to its gene expression profile, in order to make accurate pred...Aromatase inhibitors should be first-line treatment for certain type of breast cancer
Women with the type of breast cancer normally treated with tamoxifen could inste...nt for postmenopausal women with hormone-sensitive breast cancer. However, its use is associated with several side effects including endometrial cancer and bl...Book celebrates centenary of city's advances in public health
...ence. "The research programmes, including those on breast cancer, vascular disease, tuberculosis and health care evaluation have helped toward the University of Edinburgh's reputation as an international research centre. Nowadays, we focus on the study of the patterns of disease in populations; the social, ...Updated adjuvant data presented at SABCS show 30 percent reduction in recurrence
... receptor positive or receptor unknown early-stage breast cancer. AROMASIN is a hormonal therapy that belon...o play a key role in the development and growth of breast cancer. For many years, treatment with tamoxifen has been the standard hormonal therapy for postmeno...Breast MRI moderately useful for detecting breast cancer, but does not eliminate need for biopsy
In women with breast lesions that are suspicious for cancer, based on clinical examination or mammography, performing a breast MRI has high sensitivity but only moderate specificity for detecting breast cancer, but does not nec...Magnetic resonance imaging helps detect breast cancer but does not eliminate need for biopsy
A multicenter study of 821 patients referred for breast biopsy based on prior examinations that suggested ...g (MRI) distinguishes between benign and malignant breast tumors better than mammography, biopsies are still needed to confirm the diagnosis. The study, cal...Generic drug use varies widely by state, study reveals
...ems such as diabetes, asthma, high blood pressure, breast cancer and depression. Medicines through Rx Outreach cost $18 for a three-month supply or $30 for a six-month supply. Rx Outreach offers significant savings. Without access to Rx Outreach, consumers would pay an average of $100 for a 90-day supply of...Endocrine Society calls for clinical guidelines on androgens for women
...ation, though rare, should also be watched for. A breast examination before a woman starts therapy and twice a year thereafter is recommended. Other possible evaluations include hematocrit or hemoglobin determination, lipid measurement, yearly mammography and endometrial ultrasound. Some experts also sug...International trial finds benefits of breast MRI in women at high risk
...he two screening methods in women at high-risk for breast cancer. The findings of the International Breast M... high-risk young women, including those with dense breast tissue," said presenter Constance Dobbins Lehman, M.D., Ph.D., assistant professor and director of b...Study finds continued reduction in breast cancer incidence associated with longer use of raloxifene
...to be associated with more than a 50% reduction in breast cancer incidence beyond the first 4 years of treat... raloxifene was associated with a 72% reduction in breast cancer incidence compared with placebo. The Continuing Outcomes Relevant to Evista (CORE) trial was ...Tamoxifen's risks similar in African American and white women
...and white women who are treated with tamoxifen for breast cancer appear to have the same risks of contralateral breast cancer and thromboembolic events, according to a new study in the December 1 issue of the Journal o...