Statement from Dr. Claude Lenfant, director, NHLBI and Dr. Phillip Gorden, director, NIDDK
...eart disease, stroke, peripheral arterial disease, cardiomyopathy andcongestive heart failure). Indeed, cardiovascular complications are now theleading causes of illness and death in the diabetic patient. Type 2 diabetes, the most common form of the disease, affects approximately 90percent of the 10.3 million Amer...Gene discovery shows heart failure cause, suggests treatments and screening potential
...ave discovered how a genetic defect causes dilated cardiomyopathy (DCM), a form of heart failure that claims 10,000 ...symptoms but lessen heart muscle damage in dilated cardiomyopathy patients with this genetic abnormality," says Timothy M. Olson, M.D., a Mayo Clinic cardiovascular d...Annals of Internal Medicine tip sheet Feb. 5, 2002
...e. Most doctors believe that people with alcoholic cardiomyopathy (disease of the heart muscle) should avoid all alcohol. A four-year study of 55 alcoholic men with cardiomyopathy found that the hearts of men who continued drinking heavily progressively deteriorated, and 10 died ...A few drinks a day do no harm to the alcoholic heart
... treat alcohol-related diseases such as cirrhosis, cardiomyopathy and pancreatitis. Others, he says, believe that so-called moderate drinking - two to four drinks a day - may be okay. In the study, Dr. Rubin and his co-workers looked at 55 alcoholic men living in Barcelona, Spain, who suffered from heart failure....Myocarditis plus pulmonary hypertension means transplant sooner
...factors) of the disease important, but the form of cardiomyopathy is important as well, says Edward K. Kasper, M.D.,...atic analysis of hemodynamic data in patients with cardiomyopathy and congestive heart failure. Researchers studied 1,134 patients (455 women and 679 men), average a...Doppler test detects those with gene for early heart enlargement risk
...al of the American Heart Association. Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disorder, meaning t...an accompanying editorial: "Familial hypertrophic cardiomyopathy is a most unusual and puzzling disease. The heart is supernormal and thus not infrequently seen in ...Heart, heart-lung and lung transplant recipients can have successful pregnancies
...children inherited a heart problem - mitochondrial cardiomyopathy - from the mother. Of the three groups, lung transplant patients seemed to be at the highest risk for complications during pregnancy. According to Dr. Armenti, in the last 11 years of studying solid organ transplant groups, women have consistently ha...Jefferson scientist links gene to alcoholic's vulnerability to heart failure
... allele have a 16 times greater risk of developing cardiomyopathy compared to the same individuals who drank just as much but had one copy of the I gene," he says. Nearly 60 percent of those with heart failure had two copies of the D allele, compared to only three, or 10 percent, of those individuals with heart fai...Depression increases risk for some heart transplant patients
...s who received a heart transplant, 40 for ischemic cardiomyopathy and 63 for dilated cardiomyopathy. Interviews to a...oms during the waiting period," says Zipfel. "Both cardiomyopathy subgroups showed significantly increased levels of psychological distress compared with health contr...New data suggests chemotherapy patients benefit from heart failure treatment
...ass IV heart failure evaluated in M. D. Anderson's cardiomyopathy clinic. Cancer diagnosis, ejection fraction, reco...iagnosed at initial evaluation in M. D. Anderson's cardiomyopathy clinic. All 16 patients received standard combination therapy for heart failure, which included ACE...Studies describe heart disease following smallpox vaccination
...y-four cases of pericarditis, myocarditis, dilated cardiomyopathy or acute coronary syndromes (heart attack or chest pain known as angina) were identified among 37,876 U.S. civilian healthcare workers vaccinated as part of the nation's bioterrorism readiness program. Twenty-two patients had pericarditis or myocard...Defibrillators may improve survival in non-ischemic cardiomyopathy
...e the risk of sudden cardiac death in non-ischemic cardiomyopathy patients and tend to reduce all-cause mortality," Kadish said. "This finding was especially dramatic in Class III heart failure subjects, consistent with previous studies on preventive use of ICDs in this category of patients." In cardiomyopathy, ...Mechanical support could increase survival of children requiring heart transplantation
...n Hospital, Newcastle) for children with end-stage cardiomyopathy awaiting heart transplantation. Over a five-year p...22 children (average age 5.7 years) with end-stage cardiomyopathy were supported by a mechanical assist device as a bridge to first heart transplantation. Just over t...Ventricular assist devices can be used as bridge to heart recovery without need for heart transplant
...udy found that when utilized in acute inflammatory cardiomyopathy or post-partum cardiomyopathy (PPCM), VAD support appears to allow long-term restoration of cardiac function. VAD support as a bri...Women with arrhythmias may also benefit from an ICD
...ll enrolled patients had mild to moderately severe cardiomyopathy with lowered left ventricular function due to non-ischemic heart failure. Patients were randomized to standard medical drug therapy including ACE (angiotensin converting enzyme) inhibitors and beta blockers or standard drug therapy plus ICD placemen...Stem cells to the rescue - or not?
...mice lacking delta-sarcoglycan an animal model of cardiomyopathy and muscular dystrophy to determine whether these stem cells would be recruited to skeletal and cardiac muscle to restore delta -sarcoglycan expression. Surprisingly, upon examination of many thousands of muscle cells, the authors found that while d...Potential cure for lymphoma in HIV patients
...s. One patient, the oldest in the study, developed cardiomyopathy (a weakening of the heart) and kidney failure due to treatment toxicities and died a few weeks after the transplant. Opportunistic infections, such as herpes zoster and cytomegalovirus infection, also occurred in a few Patients after the transplant, ...'Broken heart' syndrome: Real, potentially deadly but recovery quick
...tack. Patients with this condition, called stress cardiomyopathy but known colloquially as "broken heart" syndrome,... should help physicians distinguish between stress cardiomyopathy and heart attacks," says study lead author and cardiologist Ilan Wittstein, M.D., an assistant profe...