Tag: "cell" at medical news
UK Researchers Receive $1.14 Million NIH Grant To Study A Molecule That May Have A Role In Diseases Involving Oxidative Cell Death
...ose (cADPR) plays in signaling pathways leading to cell
death. "Cyclic ADP-ribose is an exciting n...eCC). "Our pilot data show that it is involved in cell
responses todamage that occurs in heart attack, stroke and neurodegenerative diseases andpossibly in...
UI Study Suggests Promising Treatment For Diabetic
...s. The UI researchers have already tested theislet cell
treatment on mice with great success. "Successful use of this treatment in pregnancies complicated by diabetes wouldbe a significant advancement for these patients and a major breakthrough in thebattle against diabetes-induced birth defects," Hunter ...
Essential 'Allergy Feedback Loop' Discovered By Hopkins
...t in people with allergies, to thenumber of immune cell
IgE receptors, which, upon exposure to allergens, ... receptors, increasing from just a fewthousand per cell
to pretreatment levels of 200,000 or more over a few months. The Hopkins team documented t...
Patients Treated Successfully For Hodgkin's Disease Are At 9 Times The Risk For Developing Second Cancer
... second-cancer risk. In the study on basal cell
carcinoma alone, headed by Green, findingsshowed that the most important variable was combined treatment with radiationand chemotherapy. Of patients who received radiation therapy alone, 3 percent developedskin cancer by the age of 14, and 5....
Do Neurons Learn By Growing Thorns? Emergence Of Dendritic Spines Is Associated With Long-Term Synaptic Plasticity
...great advantages is that itminimizes damage to the cell
and it has thus for the first time made it possibleto observe single cells in living tissue for extended periods of time with highspatial resolution. Earlier studies had also already looked for changes in spinemorphology, but it was the literal searc...
Study Shows Dermatologists Are Best At Removing Skin Cancers
...ts with a common form of skin cancer knownas basal cell
carcinoma stand a better chance of being cured by ...uences. Previous research hasshown that when basil cell
carcinomas are not completely removed the first time,recurrent tumors are harder to eradicate. ...
Biochemical Marker Targets Brain Injury Leading To Movement Problems After Stroke
...g from astroke. Identifying the location of brain cell
damage provides scientists witha target site for d...nts that could halt or slow the progressionof such cell
damage in stroke patients. To locate this brain region, the scientists measured levels of a biochemi...
Compound That Mimics Insulin Might Lead To Pill For Diabetes, As Reported In The 7 May Issue Of Science
...ld need to flip the same biochemical switch in the cell
thatinsulin does. To see if any of the thousands of candidate molecules were up tothe task, the scientists incubated the various substances with cultured cellsengineered to have an abundance of insulin receptors. Then they tested thesemixtures to fin...
Wistar scientist awarded American Cancer Society grant for research on tumor killing cells
...tswith metastatic melanoma. TALL-104 is a "killer" cell
line derived from the cells of a child with a rareform of T-cell leukemia. Dr. Santoli has found that TALL-104 cells canrecognize and selectively kill malignant cells. Her research team has usedTALL-104 cells to treat pet dogs and cats with various...
Nerve Cells Live Long And Talkative Lives In Sculpted Colonies On Silicon Chips
...w in the world able to culture and studysuch nerve cell
colonies. During the course of the nearly two year...ty. The researchers can also stimulate their nerve cell
colonies at any desiredpoint, and then monitor the cellular synaptic activity that results. "We are ...
Jefferson Researchers Report Progress In Using Vaccinia-Based Vaccine For Melanoma
...cts the tumor cells, placing the GM-CSF genein the cell
cytoplasm, where it functions to make GM-CSF. To date, two advanced melanoma patients treated with the vacciniavaccine went into complete remission, only to relapse months later. Moreresearch is needed. "We need to enhance the system,...
Immunex Advances CD40 Ligand To Phase II Clinical Trial In People With Metastatic Kidney Cancer
...0L) inthe most common form of kidney cancer, renal cell
carcinoma. The company iscontinuing the developme...with a Phase II trial of CD40L in metastatic renal cell
carcinoma," said AnnHayes, M.D., senior vice president, medical development, Immunex. "Patientswith...
Sex Differences Found In Proportions Of Gray And White Matter In The Brain: Links To Differences In Cognitive Performance Seen
...lume thanwomen. Gray matter refers to the neuronal cell
bodies and their dendrites, theshort protrusions that communicate with immediately neighboring neurons in thebrain. White matter refers to the longer axons, sheathed in a white fat calledmyelin, that reach out from neurons to more distant regions of ...
Jefferson Scientists Show Tumor Characteristics May Help Explain Tumor Biology And Prognosis
...f the intricate molecular machinery that fixes the cell
when DNAdamage occurs in repetitive DNA sequences....tists also examined four other markers involved in cell
cycleregulation. For a cell
to grow, it has to pass through a cycle of particularbiochemical steps. ...
Biological Markers Found That Correlate To Esophageal Cancer Treatment Success
...2/neu, which initiates chemical signalstelling the cell
to multiply. Herceptin, a drug recently approved by the FDA totreat breast cancer patients who have excess HER-2/neu, or other agents mighteventually be useful in esophageal cancer, Harpole said. Average survival forthe 94 HER-2/neu positive patien...
Retrospective Statistical Analysis Corroborates Early Results Of Randomized Breast Cancer Trials
... ofhigh-dose chemotherapy with bone marrow or stem cell
transplants from 1989 to1995. The CALGB trials were initially conducted to compare various chemotherapyregimens, but no survival differences were seen for patients with metastaticbreast cancer, within each trial or across the trials. Berry looked ...
Breakthrough New Therapy Uses Antibody-Targeted Chemotherapy To Fight Leukemia
...es a temporarysuppression of bone marrow and blood cell
counts. CMA-676 is administered in two IV infusions fourteen days apart, and manypatients have received the drug on an outpatient basis. Unlike standardchemotherapy regimens, which involve multiple drugs, CMA-676 is given alone. Itis thus less like...
Alga-Based Compound Promises Less Bleeding On The Battlefield
...ally within seconds. Theformation of the red blood cell
plug in turn leads to a high local concentrationof platelets and clotting factors, resulting in the formation of a normal clotin a normal time frame. This product is a considerable improvement the existing technology fordressings. Currently a gauze t...
Sniffing Out The Promise Of Anti-Angiogenesis Therapy
...that newly-formedvessels are susceptible to actual cell
death if we deprive them of certainfactors. That leads us to think that if we can destroy newly formed vessels, thecells dependent on them for their supply of nutrients will also die. And that iscertainly what seems to be happening here."...
University Of Pittsburgh Cancer Institute Defines First Immunologic Markers Of Interferon Effectiveness Against Melanoma
...igh-dose IFNa2b modulated the body's expression of cell
markers calledMHC Class II antigens on tumor tissues. These markers are necessary for theanti-tumor activity of one group of immune cells, or helper T cells. High-doseinterferon also increased the response of a special set of immune cells, calledna...
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