UI Study Suggests Promising Treatment For Diabetic Pregnancies
...s. The UI researchers have already tested theislet cell treatment on mice with great success. "Successful use of this treatment in pregnancies complicated by diabetes wouldbe a significant advancement for these patients and a major breakthrough in thebattle against diabetes-induced birth defects," Hunter ...Essential 'Allergy Feedback Loop' Discovered By Hopkins
...t in people with allergies, to thenumber of immune cell IgE receptors, which, upon exposure to allergens, ... receptors, increasing from just a fewthousand per cell to pretreatment levels of 200,000 or more over a few months. The Hopkins team documented t...... second-cancer risk. In the study on basal cell carcinoma alone, headed by Green, findingsshowed that the most important variable was combined treatment with radiationand chemotherapy. Of patients who received radiation therapy alone, 3 percent developedskin cancer by the age of 14, and 5.......great advantages is that itminimizes damage to the cell and it has thus for the first time made it possibleto observe single cells in living tissue for extended periods of time with highspatial resolution. Earlier studies had also already looked for changes in spinemorphology, but it was the literal searc...Study Shows Dermatologists Are Best At Removing Skin Cancers
...ts with a common form of skin cancer knownas basal cell carcinoma stand a better chance of being cured by ...uences. Previous research hasshown that when basil cell carcinomas are not completely removed the first time,recurrent tumors are harder to eradicate. ...Biochemical Marker Targets Brain Injury Leading To Movement Problems After Stroke
...g from astroke. Identifying the location of brain cell damage provides scientists witha target site for d...nts that could halt or slow the progressionof such cell damage in stroke patients. To locate this brain region, the scientists measured levels of a biochemi......ld need to flip the same biochemical switch in the cell thatinsulin does. To see if any of the thousands of candidate molecules were up tothe task, the scientists incubated the various substances with cultured cellsengineered to have an abundance of insulin receptors. Then they tested thesemixtures to fin...Wistar scientist awarded American Cancer Society grant for research on tumor killing cells
...tswith metastatic melanoma. TALL-104 is a "killer" cell line derived from the cells of a child with a rareform of T-cell leukemia. Dr. Santoli has found that TALL-104 cells canrecognize and selectively kill malignant cells. Her research team has usedTALL-104 cells to treat pet dogs and cats with various...Nerve Cells Live Long And Talkative Lives In Sculpted Colonies On Silicon Chips
...w in the world able to culture and studysuch nerve cell colonies. During the course of the nearly two year...ty. The researchers can also stimulate their nerve cell colonies at any desiredpoint, and then monitor the cellular synaptic activity that results. "We are ...Jefferson Researchers Report Progress In Using Vaccinia-Based Vaccine For Melanoma
...cts the tumor cells, placing the GM-CSF genein the cell cytoplasm, where it functions to make GM-CSF. To date, two advanced melanoma patients treated with the vacciniavaccine went into complete remission, only to relapse months later. Moreresearch is needed. "We need to enhance the system,...Immunex Advances CD40 Ligand To Phase II Clinical Trial In People With Metastatic Kidney Cancer
...0L) inthe most common form of kidney cancer, renal cell carcinoma. The company iscontinuing the developme...with a Phase II trial of CD40L in metastatic renal cell carcinoma," said AnnHayes, M.D., senior vice president, medical development, Immunex. "Patientswith......lume thanwomen. Gray matter refers to the neuronal cell bodies and their dendrites, theshort protrusions that communicate with immediately neighboring neurons in thebrain. White matter refers to the longer axons, sheathed in a white fat calledmyelin, that reach out from neurons to more distant regions of ...Jefferson Scientists Show Tumor Characteristics May Help Explain Tumor Biology And Prognosis
...f the intricate molecular machinery that fixes the cell when DNAdamage occurs in repetitive DNA sequences....tists also examined four other markers involved in cell cycleregulation. For a cell to grow, it has to pass through a cycle of particularbiochemical steps. ...Biological Markers Found That Correlate To Esophageal Cancer Treatment Success
...2/neu, which initiates chemical signalstelling the cell to multiply. Herceptin, a drug recently approved by the FDA totreat breast cancer patients who have excess HER-2/neu, or other agents mighteventually be useful in esophageal cancer, Harpole said. Average survival forthe 94 HER-2/neu positive patien...Retrospective Statistical Analysis Corroborates Early Results Of Randomized Breast Cancer Trials
... ofhigh-dose chemotherapy with bone marrow or stem cell transplants from 1989 to1995. The CALGB trials were initially conducted to compare various chemotherapyregimens, but no survival differences were seen for patients with metastaticbreast cancer, within each trial or across the trials. Berry looked ...Breakthrough New Therapy Uses Antibody-Targeted Chemotherapy To Fight Leukemia
...es a temporarysuppression of bone marrow and blood cell counts. CMA-676 is administered in two IV infusions fourteen days apart, and manypatients have received the drug on an outpatient basis. Unlike standardchemotherapy regimens, which involve multiple drugs, CMA-676 is given alone. Itis thus less like...Alga-Based Compound Promises Less Bleeding On The Battlefield
...ally within seconds. Theformation of the red blood cell plug in turn leads to a high local concentrationof platelets and clotting factors, resulting in the formation of a normal clotin a normal time frame. This product is a considerable improvement the existing technology fordressings. Currently a gauze t......that newly-formedvessels are susceptible to actual cell death if we deprive them of certainfactors. That leads us to think that if we can destroy newly formed vessels, thecells dependent on them for their supply of nutrients will also die. And that iscertainly what seems to be happening here."......igh-dose IFNa2b modulated the body's expression of cell markers calledMHC Class II antigens on tumor tissues. These markers are necessary for theanti-tumor activity of one group of immune cells, or helper T cells. High-doseinterferon also increased the response of a special set of immune cells, calledna...