Tag: "cells" at medical news
Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
...orize that leptin remains elevated because the fat cells
neverreceive its "slimming" signal. In studying ...nergic agonist would stimulate the receptor on fat cells
and initiate the burning of storedfat." Based on results of the first study, Collins and Surwit, p...
AIDS Treatments Seek To Eradicate Virus, Restore Immunity
...e thymus makes and educates a wide range of immune cells
to fightspecific infections," Markert said. "As HI...ht patients by giving them massive doses of immune cells
during theircombination drug therapy, according to cellular immunologist Kent Weinhold. Cyt...
Shark-Liver Substance May Slow Growth Of Brain Tumors
...hes containing central nervous system blood vessel cells
from cows and squalamine alone to lab dishes conta...y up to 83 percent after two days, while the tumor cells
treated with squalamine were unaffected. Results of a second study showed that time-release capsules...
DNA Imaging to Design Better Drugs
...t more closelyresemble the genetic material in the cells
of living organisms. Traditional methods that derive information from longer DNA strandsinclude linear and circular dichroism, viscometry and sedimentation.These methods are generally reliable when ligands bind by conventionalintercalative or minor ...
Discovery Hints At Multitude Of New Targets For Drugs
...alth Service. The researchers used living cells
and test tube preparations to analyzehow a range of compounds known to plug into the progesterone receptor affectedits action. Compounds that plug into receptors are known as ligands. Steroid receptorsare complex proteins that are the princi...
Scientists Produce New Anti-Malarial Compound
...hungry carbon free radical. Carbon radicals damage cells
insidethe parasite by stealing electrons and breaking molecular bonds,making the drug toxic to the malaria parasite. "Our understanding of that mechanism has allowed us to designstructurally simpler compounds that would follow that chemicalmechanism,...
Fertilization Protein Structure To AID in Leukemia Treatment
...ze the messenger. In leukemia, white blood cells
have a signaling protein, called CD38, which in normal cells
is only present in early stages of their development. Because a CD38 molecule has a remarkable simi...
Means To Predict Which HIV+ Infants Will Rapidly Develop AIDS Outlined By Emory University Researchers
...lls. In particular, it produces the CD4+ helper T cells
that are depleted by the AIDS virus. It also produces CD8+ cytotoxic T cells. Both types of cells
are involved in resistance to HIV, as well as to many other microorganisms. The researchers postula...
KUMC Researchers Announce Breakthrough Method For Predicting Epileptic Seizures
...in. This scarring acts as an irritant to the nerve cells
which can trigger an abnormal electrical discharge, causing a seizure. For patients with epilepsy, the implications of being able to reliably predict the onset of a seizure holds the promise for new, effective ways of combating epilepsy. "Thi...
ACTG 315 Preliminary Results: Drug Cocktail Restores Partial Immune Function
...d womenwith CD4+ T-cell counts between 100 and 300 cells
per cubic millimeter(mm 3 ) of blood. To be eligi...Lederman's group found that the increase in CD4+ T cells
couldbe attributed to both more memory cells
(those that have encounteredHIV before) and more na&ium...
NIAID Stops AIDS Study Prematurely Because Drug 'Cocktail' Boosts Survival
...osted levels of CD4 cells, the infection- fighting cells
the virus attacks and slowly destroys. Volunteers in ACTG 320, randomly assigned to different treatment groups, all had CD4 cell counts below 200 per cubic millimeter of blood when the study began, while a normal count is above 500 per cubic millime...
Antimicrobial "Bug Spray" Found In Human Lung Cells
...is (CF) have found a natural "bug spray" that lung cells
"squirt" on attacking bacteria. The "spray", ...ctions via the classical immune system--B cells, T cells
and other immune cells," says Pete Pedersen, Ph.D., Hopkins professor of biological chemistry. "Bu...
New Drug For Parkinson's Disease Proves Effective, Study Finds
...inson's disease, in which several hundred thousand cells
in a tiny region of the brain die for unknown reas... agonists, which mimic dopamine and stimulatebrain cells
just as the natural neurotransmitter would. Dopamineagonists on the market today include bromocripte...
Mother's Milk: Nutrition And Nurture For Infants -- And The Best Defense Against Disease
...ays a significant role in stimulatingimmune-system cells
in the infant. And while prolactin is primarily pr...members of a familyof proteins secreted by various cells
that stimulate, inhibit, or otherwiseregulate immune-system cells. Many of these may be produced by ...
New Approach To Multidrug Resistance
...restore the effectivenessof chemotherapy in cancer cells
that have become resistant to its effects. Thetech...A together. The researchers treated drug-resistant cells
with a low dose of the cancer drugmitomycin C, waited 24 hours, then administered a second chemother...
Duke Obtains FDA Designation For Pompe Disease Therapy
...cted into infants will be taken up by their muscle cells
andrestore normal glycogen levels. This treatment, known as an enzyme replacementtherapy, would be required for the rest of these patients' lives. He said he hopes to expand the treatment to additional Pompe diseasepatients as safety and efficacy ar...
New Test May Improve Treatment Of Kidney Disease
...wers to the puzzle. By harvesting white blood cells
from patients, placing the cells
in tissueculture plates andexposing them to common steroid and immunosuppressant medications, scient...
Antioxidant-Enhancing Drug Partly Rescues Noise-Induced Hearing Loss
... partly by free-radicaloxidative damage to sensory cells
in the inner ear, and a drug called R-PIA canlesse... killsensory cells. To defend themselves, sensory cells
express a rush ofglutathione, an antioxidant that absorbs free radicals. R-PIA was found toincrease...
Cancer Protection Compound Abundant In Broccoli Sprouts
...Man-made compounds that increase the resistance of cells
and tissues tocarcinogens arecurrently under development, but will require years of clinical trials todetermine safety andefficacy," Talalay notes. "For now, we may get faster and better impact bylooking at dietarymeans of supplying that protection....
'Bathtub' Equation Aids Diabetes Research
...e todescribe what's happening with beta cells, the cells
which make the hormone,insulin. The number of new cells
forming, minus the number dying, equals therate of change in the number of cells. It's simple math. ...
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