Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
...r of fat cell size, so that when the cellreaches a certain proportion, it sends a signal that elicits some metabolic response to eliminatefat," Surwit said. Leptin travels through the bloodstream to the brain, where it targets clustersof neurons in the hypothalamus, a brain structure that regulates food in...Maternal Exposure To Crack Cocaine Produces Stressed Newborns
...rgy,appear to be more stressed, and fail to follow certain stimuli, such as arattle or bell, compared to non-exposed infants. The Brown researchers think the findings result from the combined action ofcocaine with alcohol and marijuana. Alcohol can boost the effects of cocaine,and most of the crack-smoking ...Discovery Hints At Multitude Of New Targets For Drugs
...drugs could causethe same receptor to trigger only certain of its normal effects in the body,but not others. The finding, if confirmed, could point the way to a new wave of drugs withfewer side effects for contraception, hormone replacement therapy, breastand prostate cancer, inflammation, osteoporo...What Makes Tics Tick? Clues Found In Tourette Twins' Caudates
... such symptom differences to "supersensitivity" of certain neurotransmitter receptors in the brain structure responsible for carrying out automatic behaviors. They suggest that this dysfunction may underlie the compulsion to act out the sudden movements and vocalizations that characterize Tourette Syndrome......r microorganisms. The researchers postulated that certain strains of the AIDS virus not only deplete mature ...tion of these cells by damaging the thymus. Thus, certain infants would exhibit particularly low levels of CD4+ and CD8+ T cells -- and would develop AIDS sym...KUMC Researchers Announce Breakthrough Method For Predicting Epileptic Seizures
...l times, the moment the seizure components reach a certain critical level signals that a seizure is about to occur. Epilepsy is caused by factors such as head trauma, brain tumors, strokes, infection, poisoning, oxygen deprivation or other events that cause scarring in the brain. This scarring acts a...Drug And Radiation Treatment May Shrink Pancreatic And Gastric Tumors
... Safran, M.D., tumor regression occurredrapidly in certain patients, often within three weeks after treatments began.After two months of treatments, tumors in several patients had decreased to asize to where they could be removed surgically. "Paclitaxel makes tumors much more sensitive to being killed by ra...Study Shows Gum Disease Increases Risk Of Future Heart Disease
...t oral bacteria can infect damaged hearts and that certain oral bacteria cause platelets to aggregate," Genco said. "We just recently put these findings together as a possible explanation of how bacteria that cause periodontal disease can also increase the risk for heart disease." Genco has been follow...Common Carbohydrates May Prove To Be Substitute For Dietary Fiber
...enefits to human and animal digestive systems from certain formsof indigestible oligosaccharides -- naturally occurring groups of carbohydratescontaining simple sugar molecules -- found in many fruits and vegetables. For years, oligosaccharides were thought to give people flatulence ordiarrhea. A 1968 study...UNC-CH Study Shows State Protects HMO Clients Poorly
...s or clinical criteria used to review the need for certain treatments or services. “This information is especially useful for individuals with special health-care needs who need to choose from competing health plans,” Silberman said. “Now, for example, lots of plans say they will cover servi...Mother's Milk: Nutrition And Nurture For Infants -- And The Best Defense Against Disease
...osed mechanism to explain this observation is that certain antibodies inbreast milk may mimic bacterial and viral proteins. Such mimicry would have theeffect of priming the infant immune system to respond more vigorously when laterexposed to actual pathogen proteins. A number of studies over the last......ng. Forexample, "young drivers who participated in certain drivereducation courses learned more demonstrable driving skills thanthose who didn't take the course. Role-playing and intervention-oriented classes helped the youths develop skills to resistpressures to drink and drive, to resist riding with a drin...New Test May Improve Treatment Of Kidney Disease
...some patients with kidney diseases respond well to certain medicationsand others do nothas continued to stump physicians. With no means to test the medicationsbesides trial and error,finding the right treatment is often a frustrating experience for physicians andtheir patients. Now, research at Johns H...Many Medical Screening Tests May Be Unnecessary.
...nd prostate cancer---that may be ill-advised under certain circumstances. A University of Michigan physician and three co-authors explore that predicament in the article "Ethical Considerations in the Provision of Controversial Screening Tests," in the current issue of the Archives of Family Medicine . Ph...'Bathtub' Equation Aids Diabetes Research
...know about some things and how little weknow about certain simple things," she says. "We may not be close to findinga cure, but we're not that far off from improving prevention strategies."...NIH Honors Emory Researcher With Merit Award For Work On Renin-Angiotensin System
...ated by a testis-specificpromoter located within a certain portion of the somatic ACE gene-a findinglater confirmed in the human gene. To determine whether testis ACE has any real importance in malereproduction, Bernstein created recombinant knockout mice containing no somaticor testis ACE gene. He fo...Affordable, Hand-Held Biosensor For Diagnostics
...nother biosensor provedsensitive to the binding of certain antibodies, manufactured by the body'simmune system, to small amounts of their specific antigens--a class of moleculesproduced by invading organisms that include viruses, bacteria, in addition totoxins and allergens. The biosensor was able to...Cattle: Latest Weapon In The War On Cancer?
...stry. "Overseas scientists have demonstrated that certain extracts ofshark cartilage, injected into tumours, cause them to regress. They alsoappear to inhibit the development of blood vessels to the cancer, whichallows them to spread round the body," Dr Harper explains. "The shark cartilage extract market...Rats Receiving Ginkgo Biloba Learn Quicker, Live 20 Percent Longer Than Controls, UB Study Finds
...ficits, using rats as an animal model. "At a certain point in our analysis, we realized that the rats who were receiving ginkgo biloba were living substantially longer than those who were not receiving the extract," said Jerrold C. Winter, Ph.D., professor of pharmacology and toxicology in UB's School ...MIT Solution To Math Problem Could Lead To Better Dental Implants, More Resistance To Missiles
...hings, offers a way to determine the properties of certain materials that willsave time for automotive factory workers who check the quality of car gears. Photo by Donna Coveney In graded materials--the focus of the MIT research--two or moredifferent materials are mixed together such that the p...