Strategy effective against drug resistant tuberculosis
... strategy for tuberculosis includes a short-course chemotherapy with combinations of first-line drugs. There is growing concern about current and future rates of multidrug-resistant (MDR) tuberculosis in the world. Little data exists to guide policy on how to best control and prevent tuberculosis in areas where d...Chronic pain treatments more effective when taken together, new study shows
...pinal disk disease, and the pain experienced after chemotherapy and mastectomies, Dr. Gilron notes. "The numbers of people affected are staggering, and the impact of the problem is devastating and costly." Diabetic neuropathy occurs in diabetes patients who experience a constant, burning pain, often in the so...Unexpected benefit seen in treating HER-2 breast cancer with new preoperative drug combo
...s M. D. Anderson Cancer Center. When combined with chemotherapy and used before surgery in early stage breast canc...neficial - eliminating 42 percent more tumors than chemotherapy alone - that the clinical trial testing of this new treatment plan was halted early, the researchers...OHSU scientists test medication to treat involuntary weight loss
...alnourished due to cachexia cannot undergo intense chemotherapy simply because their bodies are too frail to handle it. If we can prevent cachexia and keep these patients from deteriorating physically, it gives them a greater chance of surviving the disease they are fighting." This latest research breakthrough is...Mayo Clinic discovers 'new pathway' against pancreatic cancer
... activity is high -- which can cause resistance to chemotherapy drugs used to treat the disease. This new information suggests a potential means of treating pancreatic cancer by a two-pronged attack of administering the gemcitabine in combination with a drug to block GSK-3 Beta. Nearly all die within five years ...Postmenopausal breast cancer survivors at increased risk for bone fractures
...t cancer survivors and accelerated bone loss after chemotherapy for breast cancer suggesting an increased risk for fractures among breast cancer survivors, according to background information in the article. Previous studies on the risk of fractures have been inconsistent. Zhao Chen, Ph.D., M.P.H., of the Univers...Bevacizumab combined with chemotherapy prolongs survival for some patients with advanced lung cancer
...cizumab (Avastin TM ) in combination with standard chemotherapy lived longer than patients who received the same chemotherapy without bevacizumab. The clinical trial was sponsored by the National Cancer Institute (NCI), part o...Drug that hinders blood vessel growth under study in ovarian cancer
...life, Dr. Ghamande says. Also, the side effects of chemotherapy often mean well-intended patients never complete that second year. A6 may one day offer another option for these women. The current study explores the safety and efficacy of two different doses of the drug compared to placebo. Study particip...Breakthrough in medical research: New chemotherapy gives hope to brain tumour patients
...ls Group demonstrated that the addition of a novel chemotherapy agent, Temozolomide (brand name: Temodal) to radia...nce every eight weeks the common dosage for other chemotherapy drugs" "This landmark study represents the most important advance in the management of glioblastoma ...New treatment options for some difficult cancers improve survival and quality of life
... shown that surgery combined with inserting heated chemotherapy drugs directly into the abdomen can improve surviv...nation of surgery and intraperitoneal hyperthermic chemotherapy (IPHC) are tumors of the abdominal cavity that have spread from the appendix, small bowel and advanc...MRI better than current standard in assessing neoadjuvant chemotherapy for breast cancer
...ents with large palpable tumors are now undergoing chemotherapy before surgery in an effort to reduce the size of ...r tumor, and MRI is the best way to predict if the chemotherapy is working, preliminary results of a study show. If the chemotherapy is successful, then the woman m...Cryoablation is effective in treating cancer patients' pain
... the patient had multi-focal disease. In addition, chemotherapy or radiation therapy had not been successful in controlling these areas of symptomatic disease. Each patient underwent CT-guided percutaneous cryoablation. Cryoapplicators were inserted into the tumor area, and the tumor and adjacent areas were froze...Brain tumor with dismal prognosis in infants can be cured in older children
...ed by upfront treatment with radiation followed by chemotherapy using so-called alkylating agents (cyclophosphamid...perienced relapse of ATRT could be saved using ICE chemotherapy (ifosfamide, carboplatin- and etoposide). Other authors of the report are Tanya M. Tekautz, Christin...Both inherited traits and tumor mutations affect response to treatment of leukemia
The outcome of chemotherapy treatment for acute lymphoblastic leukemia (ALL) d...was to determine whether the success or failure of chemotherapy for ALL was linked to any of 16 common genetic polymorphisms in genes that interact with the ALL che...Older women can benefit from chemotherapy to treat breast cancer
Age alone should not prohibit the use of chemotherapy regimens in older women with breast cancer who are...article. "Systemic adjuvant (secondary treatment) chemotherapy in women with early-stage breast cancer significantly improves both relapse-free and overall surviva...Plant derivative attacks the roots of leukemia
...tem cells reacted to parthenolide, versus a common chemotherapy drug called cytarabine. The result: parthenolide selectively killed the leukemia cells while sparing the normal cells better than cytarabine. Scientists believe parthenolide might also make cancer more sensitive to other anti-tumor agents. And, the ...Protein that promotes survival of stem cells might be key to poor leukemia prognosis
...to rebuild the blood system of patients undergoing chemotherapy and radiation for cancer. Opferman completed work ... leukemia from undergoing apoptosis in response to chemotherapy or radiation. This makes the leukemia cells resistant to treatments designed to damage the cell so i...Acquired resistance to chemotherapy is a major obstacle to successful cancer treatment. Understanding the mechanisms by which tumors become resistant to a particular agent is key to identifying new drugs or combination regimens. In an upcoming article in the international open-access j...Gene signature can predict breast cancer spread
...tive breast cancer who had not received hormone or chemotherapy after their initial treatment. The sample group co...udies, the recommendation of additional hormone or chemotherapy in patients with lymph-node negative breast cancer could be guided by this prognostic signature." In...Study examines effect of managed care on quality of care for cancer patients
...ter breast-conserving surgery, receipt of adjuvant chemotherapy for stage III colorectal cancer, or surveillance colonoscopy after treatment for colorectal cancer. However, market share increases were associated with increased rates of one quality-of-care measure, surveillance of colorectal cancer patients with c...