Ovarian Hormone Could Play Key Role In Easier, Safer Childbirth
...atassures that it enters the bloodstream." Initial clinical trials being conducted by Connectics Corp. of Palo Alto,Calif., have indicated that genetically engineeredhuman relaxin softens affected skin in people suffering from scleroderma, adisease characterized by an increase incollagen fibers in the skin....Pairing Two Drugs With Angioplasty May Offer Best Success In Treating Heart Attacks
...he findings are confirmed and expanded in a larger clinical trial,pairing the drugs with angioplasty may offer a new standard of care for heartattacks, said the trial leader, Dr. Magnus Ohman, a cardiologist at the DukeClinical Research Institute. "Most patients now receive either a clot-busting drug......the results are dramaticenough to warrant a larger clinical trial. "By using existing technologies in a novel way, we were able todemonstrate significant cost savings," Eisenstein said. "At the same time, theuse of these technologies should help give emergency room physicians greaterconfidence in the...Drip And Ship: Start Drug Early, Especially If Plan To Transfer Heart Patient To Larger Hospital
...onof whether or not to transfer should be based on clinical considerations. Insome cases, it appears that starting the drug at the smaller hospital may evenalleviate the need to transfer altogether." Greenbaum, a cardiology fellow at the DCRI, prepared the results of hisstudy for presentation Tuesday ......ts are still in development and have not undergone clinical trials. Cramer said tobacco has the potential to serve as the host for many other pharmaceutical proteins as well. Tobacco is exceptionally suited for use in producing pharmaceuticals because it is one of the most productive crops in growing leaf b...Hospital Stays Longer Than Three Days For 'Simple' Heart Attacks May Not Be Cost Effective
... of the first attempts to quantify what is thereal clinical benefit of a day in the hospital." The...40,000 patientswho had participated in the GUSTO-I clinical trial between 1990 and 1993. Theprimary purpose of that trial was to compare the effectiveness of tw...Researchers Splice Severed Spinal Cords
...the procedure in live animals. They plan toconduct clinical trials in natural cases of paraplegia in dogs early in 1999,but human clinical trials are at least two years away. The isolated spinal cords remain viable for about 36 hours a...... patients. Thesewere the results of two Phase III clinical trials of zanamivir reported today atthe 36th meeting of the Infectious Diseases Society of America (IDSA) in Denver,Colorado, USA (November 12-15, 1998). The first study, conducted in Europe in the winter of 1997/8, recruited 356patients, of whom 78...Pursuing The Next Generation Of Arthritis Treatment
...eness." Eventually, between five and ten clinical trials will be conductedsimultaneously at the New ...and Drug Administration. The other current clinical trial is the first test of a promising newtreatment for systemic lupus, a potentially life-threateni...National Clinical Trial To Test Effectiveness Of Antibiotic Treatment For Coronary Artery Disease
...be effectivelytreated with antibiotics? A national clinical trial directed by the Universityof Washington and ...lic Health andCommunity Medicine. Approximately 27 clinical centers nationwide willparticipate in the study. "The idea of giving antibiotics to treat a......cluding protease inhibitors, hasrevolutionized the clinical management of HIV, protease inhibitors have becomean integral component of the clinical strategy to treat HIV infection. "Giventhat many HIV-infected individuals will be treated with prot...First Drug Shown Effective For Treating Chronic Forms Of Major Depression
...psychiatric clinics at 10 academic medical and two clinical researchcenters. Before entering the study, the patients had responded positively tosertraline in a 12-week trial and had continued to respond well in a four-month extended treatment. In the study, 77 patients maintained sertraline ...New Drug Boosts The Power Of Traditional Cancer Therapies, UF Animal Studies Show
...rmaceutical company announced it has begun Phase I clinical trials in human patients with advanced cancers to ...atin. Following successful Phase I trials, further clinical testing would be required to measure the drug's effectiveness, to determine dosages and to compare i......ssion. The researchers noted significant clinical improvement by patients whoreceived either antidep...hotherapy. Treatment type was unrelatedto rate of clinical improvement in those with a higher level of majordepression, since both samples had identical scores...Now Is Time To Design Brain-Saving Drugs Specifically For Children, UCSF Neurologist Says
...s network would coordinate nationwide research and clinical trialsaimed to eliminate brain damage among newborns. However, before clinical trials could go forth on any scale, drug companies alsowould have to make a commitment to test new t...A Trip To The Dentist Could Cause Symptoms In Asthmatic Kids
...nt of a master of science degree. She is now a clinical assistant professor of dentistry at Ohio State.... Other study co-authors included James Preisch, clinical assistant professor of pediatric dentistry at Ohio State and Children’s Hospital; Stephen...Low "Health Literacy" Increases Hospitalizations
...cines, monitoring bloodglucose levels, and keeping clinical appointments. Hospital admissions are a major factor in health care costs, accordingto David W. Baker, MD, of Case Western Reserve University and MetroHealthMedical Center in Cleveland, and his colleagues at Emory University School ofMedicine......o play againstcancer. Early results from the first clinical trial of this approach will bepresented December 5...gists meeting in MiamiBeach, Florida. This phase-1 clinical trial -- designed not to assess effectiveness but todetermine the optimal dose and measure toxicity ......tion "to be involved in a small way inresearch and clinical trials for new treatments and perhaps a cure for b...he past 12months, they also were tested in Phase I clinical trials on children withleukemias and solid tumors, and on women with breast cancer. The trialsdemon...Results of a multi-institutional clinical trial that included a UC San Franciscoresearcher i...the lead authorof the study, Charles Linker, MD, a clinical professor of medicine and directorof the UCSF-Stanford Health Care Adult Leukemia and Bone Marrow Tr...