Tag: "compounds" at medical news
Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
...lof experience developing sensors which can detect compounds
atextremely low concentrations, as low as 3,000 mo...o detect theimaging agent in the presence of other compounds
in tissue. Thenwe insert it into the organ of the animal, and make ameasurement. That's how we do it...
Discovery Hints At Multitude Of New Targets For Drugs
...nd test tube preparations to analyzehow a range of compounds
known to plug into the progesterone receptor affec...y view. The researchers foundthat some of the test compounds
were "agonists" of the receptor,switching it on. And others were "antagonists," blocking itsaction....
Scientists Produce New Anti-Malarial Compound
...e a year. Chemists were able to synthesize the new compounds
after learninghow another, more expensive and diff... malaria drugworks at the molecular level. The new compounds
use the samemechanism to kill the parasite that causes malaria, but they aremuch less expensive and ...
Antimicrobial "Bug Spray" Found In Human Lung Cells
...des that kill bacteria." After the first such compounds
were identified in cells from frog skin and cow throats by researchers at other institutions Young Hee Ko, a research associate in Pedersen's lab, suspected that CF jammed the "nozzle" on a similar bug spray. "That nozzle is a channel on the surface...
Cancer Protection Compound Abundant In Broccoli Sprouts
...contain 20 to 50 times theamount ofchemoprotective compounds
found in mature broccoli heads, and may offer asim... A systematic search for dietary sources of compounds
that increaseresistance tocancer-causing agents led the Hopkins group to focus on naturally occurrin...
Affordable, Hand-Held Biosensor For Diagnostics
...ecting a wide range of medicallyimportant chemical compounds
has been created by a team of researchers from TheScripps Research Institute (TSRI) of La Jolla, California and the University ofCalifornia, San Diego. The biosensor, which changes colors to signal the presence of specificmolecules, may repre...
Targon And Duke Cancer Center Sign $3.75 Million Agreement To Produce Advanced Anti-Cancer Drugs
...ill support pre-clinicaland clinical trials of new compounds
developed at Duke, or other institutions, which ar...biology, in pre-clinical laboratory testing of new compounds
and finally inclinical testing," he said. Michael Sember, Targon's Chairman and CEO, comment...
Chemists Closing In On Commercial Potential Of Alkanes
...tion reaction at room temperature. Alkanes are compounds
of carbon and hydrogen atoms held together by sing...d measure the kinetics at room temperaturewith the compounds
dissolved in a hydrocarbon solvent. Frei supplied a Fouriertransform infrared spectrometer (FTIR) th...
Chemist Turns To Self-Assembly To Create New Drugs
...hengoes to work to "decide" which of the resulting compounds
bestmatches the prospective drug's DNA, RNA, or pr...ny pharmaceutical firms areusing to ferret out new compounds
to take aim at disease-producing DNA and RNA sequences and proteins. Miller and graduatestudents Bry...
Tighter Chemical Binding = Better Meds
... L. Jorgensen, whospecializes in tweaking chemical compounds
to tighten their ties to targetproteins. Using sophisticated computer graphics and his knowledge of thethree-dimensional structure of protein molecules, Jorgensen consults withmajor pharmaceutical firms regarding new methods of rational drug design....
X-Rays: How Big A Risk To Kids? UF Researchers Seek Answers
... made outof: a polyester resin mixed with chemical compounds
to mimic soft organ,lung and bone tissue under an X-ray. "They absorb X-rays just like the real tissues would," said DavidHintenlang, Kathleen Hintenlang's husband and a professor in the nuclearand radiological engineering department and spec...
BioNumerik Reports Preclinical Antitumor Data On Two Novel Supercomputer Engineered Anticancer Agents At 89th Annual AACR Conference
...complement the discovery and optimization of novel compounds
for laboratorysynthesis and preclinical testing. ... than 6 years, the Companyhas rapidly advanced two compounds
into human clinical trials and a third newcompound into late preclinical development. *** Editor's ...
New Research In Battling Alzheimer's Impact On Memory
...ver, Ph.D.,researchers are currently testing their compounds
in mice with amyloid-ladenspleens. After molecular modeling simulations and extensive structure-activityrelationship determinations, the Canadian group has found a lead molecule thatlooks very promising. It "can mop it all up," says Weaver. He cau...
Researchers Synthesize Compounds For New Class Of Antibiotics
...ceuticals, Inc., have successfully synthesized two compounds
that open thedoor to the development of an entirel... strains of bacteria.Before this breakthrough, the compounds
could only be isolated from theirbacterial source, a process that yielded quantities too small to be...
Synthetic Detergent Found To Fight Multi-Drug Resistance
... detergents." "Detergents are composed of compounds
that can be chemically synthesizedto suit your nee...tep is for clinicians to evaluate the use of these compounds
in treatingcancer." Charuk collected his own urine for three years to determine the role of...
Crystal Structure Of gp120 Reveals HIV In Action
... potential forthe information to be used to design compounds
that interfere and block thatinteraction," says Wayne Hendrickson, Ph.D., professor of biochemistry andmolecular biophysics at Columbia University and a Howard Hughes MedicalInstitute Investigator. Adds Peter Kwong, Ph.D., associate research scientis...
Montana Fungus The First But Not The Best
...sity around the world. The microbes may make other compounds
that couldbe useful to human medicine, he said. "Given the large numbers and varieties of higher plants, the numbers andkinds of their associated microfungi must be enormous," Strobel wrote....
Study Finds St. John's Wort Can Cut Alcohol Consumption
...t, Rezvani said. Still,combining several effective compounds
that alter brain chemistry safely probablycould lessen its severity in people motivated to change. The U.S. Food and Drug Administration has not approved St. John's wortfor medical purposes. Not...
Old Drugs, New Tricks
...stion of large amountsof fat). Fibrates, synthetic compounds
that bind to this receptor, stimulatePPARa activity and thereby reinforce its lipid-lowering action. The INSERM researchers showed that PPARa receptors are also present in vascularmuscle cells, which participate in the formation of atheroma plaque a...
Three INEEL Inventions Win International Recognition
... that malting ofcereal grains activates biological compounds
that functions to protect the plantagainst disease caused by bacteria and fungi. These protective mechanisms occurnaturally during germination, which malting simulates. The Malt-based Antimicrobial offers the application breadth of chemicalpesticides...
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