Heat-controlled drug implants offer hope for future
...ry. The results add to a decade's worth of work in controlled and targeted drug delivery. Lyon's usage of using films assembled from microparticles allows more control over drug release than films previously made in monolithic form. The insulin tests, said Lyon, serve as proof of a concept that this method of ...Smallpox vaccine can be diluted and still be effective, expanding supply if needed
...the smallpox vaccine in a double-blind, randomized controlled trial conducted between October 2002 and February 2003. Test subjects, aged 18 to 32 years, were given one of three strengths of the Aventis Pasteur smallpox vaccine (APSV): undiluted, a one to five dilution, or a one to ten dilution. The researchers...Health benefits of citrus topic at American Chemical Society meeting in Philadelphia
...nced that they had confirmed for the first time in controlled human studies that grapefruit actually does promot...ng grapefruit juice may help reduce the risk. In a controlled study involving 49 smokers, researchers at the University of Hawaii found that drinking three 6-ounc...Children walk nearly as much as their grandparents did
... whereas 21st century children are more strictly controlled by their parents. Few of the young children interviewed had dealt with risk, and compared to earlier generations they have not had the opportunity to learn to negotiate and to deal with challenges. While the children who were aged 10/11 when int......a history of hypersensitivity to abacavir. In one controlled study (CNA30021), more patients taking ZIAGEN 600 mg once daily had severe hypersensitivity reactions, as well as hypotension as part of a hypersensitivity reaction, compared to patients taking ZIAGEN 300 mg twice daily. Whe...ASU researchers demonstrate new nanotech effect - moving water molecules by light
...d also magnify the small change in water repelling controlled by light to a level that can overcome the hysteresis, or the attraction, that causes water to stick even when a drop is pushed along, " Picraux said. "Rohit Rosario mathematically derived the theory for surface change amplification and proved it in t...July/August 2004 Annals of Family Medicine tip sheet
...ponsibilities among office staff. In a randomized controlled trial involving eight primary care clinics, the in...CT-Depression project, which includes a randomized controlled trial to test a new evidence-based clinical model for treating depression. The model is currently b...Update on cholesterol guidelines: more-intensive treatment options for higher risk patients
...actors (especially diabetes), or severe and poorly controlled risk factors (e.g., continued smoking), or metabolic syndrome (a constellation of risk factors associated with obesity including high triglycerides and low HDL). Patients hospitalized for acute coronary syndromes such as heart attack are also at ...Eye drops may delay or prevent glaucoma in African Americans at higher risk
...owever, if detected early, glaucoma can usually be controlled and serious vision loss prevented. Comprehensive dilated eye examinations are recommended at least once every two years for African Americans over age 40 and all people over age 60. "This is the first study to recruit large numbers of African Americ...National study shows 82 percent of U.S. homes have mouse allergens
...rban, suburban, rural). The selection of homes was controlled to be a representative sample of U.S. homes. For statistics derived from the 831 homes, the contribution from each home was weighted as necessary to ensure that the statistics are representative of the U.S. population. Dust samples used in the study ...Studies show ACTOS(R) (pioglitazone HCl) has positive effects on various components of dyslipidemia
.... In each of the four trials, patients with poorly controlled type 2 diabetes were randomized to receive monotherapy consisting of ACTOS, metformin or a sulfonylurea (gliclazide), or a combination of ACTOS with these two agents. Analysis of the data showed that, in addition to reducing hyperglycemia by address...Incentive-based intervention with nutritional component improves health status of children in Mexico
...ing malnutrition interventions are effective under controlled conditions; however, little information is available on their effectiveness in large-scale programs. Rivera and colleagues conducted a study to determine the short-term nutritional impact of the large-scale, incentive-based development welfare progra...COX-2 inhibitor could be safest anti-inflammatory drug for older people
...rants the implementation of large-scale randomised controlled trials to examine this issue further"....When it comes to cancer prognosis, it's not just the tumor that matters
... recorded in cancer registries rather than through controlled clinical trials," says Piccirillo, who is an assoc...disease severity. An individual with mild diabetes controlled by dietary restrictions receives the same code as an individual with severe diabetes taking daily in......internationally are underrepresented in randomized controlled trials (RCTs) published in leading medical journal...obal burden of disease and examined the randomized controlled trials published in 6 leading international general medical journals (including CMAJ) that same year...Weekly cycles of once-daily anti-HIV drugs could reduce cost of HIV treatment
...urce-limited settings. In this regard, randomized, controlled clinical trials are being conducted in various sites in the United States and other countries to evaluate the clinical usefulness of short-cycle SIT."...New data supports CellCept's position as a world leader in solid organ transplantation
...udy: a randomised, open, multicentre, prospective, controlled study. Abstract 462, ATC 2004. Further data shows CellCept's CNI-sparing benefit in patients with impaired graft kidney function given a 50% reduced dose of CNI, within a CellCept-based immunosuppressant regimen. Results indicate that over two years...Research hones in on therapies and diagnosis of bowel diseases
...lead author of the study. "We hope that a larger, controlled trial will confirm these results and help make this potentially valuable therapy available to patients who can benefit from it." Randomized, Double-Blind, Placebo Controlled, Parallel Arm, Safety and Efficacy Trial of Once-Daily, Oral OPC-6535 in th...Breakthrough therapies treat Crohn's disease
...ational trial, researchers conducted a randomized, controlled study (ENACT-2) to determine whether a six-month regimen of the drug could maintain the clinical response/remission achieved by the previous study. ENACT-2 studied 339 adult subjects with Crohns disease (CD) from ENACT-1 who had achieved a response...... low-fat diet." The study is the first randomized, controlled trial of an Atkins-style diet approach, which includes vitamin and nutritional supplements. Along with losing an average of 26 pounds, dieters assigned to the low-carbohydrate plan lost more body fat, and lowered their triglyceride levels and raised ...