Body fat and its role in breast cancer
...r in women not using HRT, but waist circumference, controlled for overall body fat (BMI), was not significantly related to increased breast cancer risk, neither in post- nor in premenopausal women. The authors conclude: "Overweight is one of the few modifiable breast cancer risk factors and thus an important m...Computer system makes 'chain' of health care stronger, safer
...e Discharge Navigator, and discuss the randomized, controlled study involving 700 patients that shows its value. Among their findings: The system reduced by six days the time it took for a patient's personal physician to get a report on the patient's hospital stay; far more information was entered into a patien...New research in atrial fibrillation
...m from becoming irregular, or to try to maintain a controlled heart rate. But we are still far from having an optimal therapy. There is a tremendous need for new ways to treat this condition. "A number of innovative approaches are in different stages of development," said Dr. Donahue. He spoke today at an Amer...Statins show early promise for treating multiple sclerosis
...of statins lend support to the case for randomised controlled clinical trials to establish the safety and effica... of statins in MS is currently insufficient, large controlled clinical trials are needed. The first of these trials is about to start"....New research suggests two brain areas critical for short-term memory
...risingly, we found that the shortest memories were controlled almost exclusively by the subiculum, which is exactly opposite from what was previously believed," said Deadwyler. "For the first 10 to 15 seconds of the task used to examine this in rats, we found that the memory function of the hippocampus actually...Obesity reversed in mice by destroying blood vessels that service fat cells
...romote the concept that adipose tissue mass may be controlled by angiogenesis (the process of new blood vessel formation from established ones). Given their belief that blood vessels that feed adipose tissue are different from all other kinds of blood vessels, the M.D. Anderson researchers set out to find a pro...Drug for depression helps irritable bowel syndrome, according to Pittsburgh study
...SRI), has been reported in case reports but not in controlled studies. SSRIs are considered first line treatments in psychiatric illnesses such as major depression and generalized anxiety disorder, which are found in 50 to 90 percent of patients with IBS, according to Dr. Arnold, who is a gastroenterologist at ...Seroquel: New data show efficacy and tolerablity in bipolar depression
...n as the BOLDER study, was a double-blind, placebo controlled trial involving 542 patients with bipolar I and II disorders who were randomised to receive 8 weeks of treatment with either a fixed dose of SEROQUEL (300mg/d, 600mg/d administered once-daily) or placebo. The results of the trial show: 1,2 Patien...Alternative medicine therapy now being tested for heart disease
..., is a five-year randomized, double-blind, placebo controlled trial designed to test the effects of chelation and high dose antioxidant vitamin and mineral supplementation versus a low dose regimen. To qualify, patients must be over the age of 50 and have documented a heart attack more than six weeks prior to ...Long-term study proves ADDERALL XR is a safe and effective option to treat adults with ADHD
... on ADDERALL XR treatment in the four-week placebo controlled study. "When determining the most appropriate ADDE...nts who had received placebo during the short-term controlled study. Patients who continuously received ADDERALL XR in both studies also experienced a significan...Ongoing study evaluates pediatricians' effectivenes at violence prevention
... the study, which is the first national randomized controlled trial to test the effectiveness of a program for pediatric providers to prevent violence. Physicians will review the parent surveys for trouble spots, reinforce positive behaviors, educate families on problem areas, provide tools and skills for paren...Study finds HIV protein can drive immune cells away
... the specific interaction of gp120 with CXCR4 that controlled T cell movement, and that the same repulsion could be produced specifically with T killer cells programmed to attack HIV. The researchers then used immunized mice to look at the effects of the viral protein in vivo. One day after the mice were inje...Even drug-resistant HIV infection responds to right treatment
...ient, as long as the treatments are initiated in a controlled setting to ensure that every single dose is given every single time and to monitor and control side effects if they occur," she adds. Each patient in the Hopkins study underwent genotype analysis and any detected gene mutations were entered into the...FDA approves Enbrel to treat psoriasis
...o infection, such as those with advanced or poorly controlled diabetes Some serious infections were fatal Rare cases of tuberculosis What to do/Not to do Do not start ENBREL if you have an infection or are allergic to ENBREL or its components. Tell your doctor if you are prone to infection. Stop ENBRE...Cranberry juice may reduce risk of female urinary tract infections
...also recommend using it," Dr. Raz said. If more controlled studies of cranberries' effect on UTI do take place, Dr. Raz believes they should be varied. "In general, we need more clinical studies with different population groups, different dosages, and comparison between juice and capsules," he said. ...Bone implants could aid healing after tooth removal
...nt capable of releasing these healing factors in a controlled manner so that the proper amounts are released over the right time period at the site of interest. The implant will enable healing by stabilizing the gap and offering a welcome environment for the body's own bone cells. The implant will break down ov...Surgery for treatment of temporal lobe epilepsy varies among ethnic groups
...onstrated success rate of 60 percent in randomized controlled trials, and up to 93 percent in descriptive studies. MTS, which is among the most common causes of temporal lobe epilepsy, is characterized by cell loss and structural changes in parts of the brain called the hippocampus and amygdala. At the same tim...Preliminary results are promising in Alzheimer's gene therapy trial
...ynski. "If these effects are borne out in larger, controlled trials, this could be a significant advance over existing therapies for Alzheimer's disease." Eight volunteers diagnosed with early-stage Alzheimer's disease participated in this study, with the first surgery performed in April 2001 at UCSD's John M....CellCept associated with reduced incidence of cancer, compared to AZA, following heart transplant
...plant Registry."Though not derived from randomized controlled trials, these data indicate that the choice of maintenance immunosuppressive regimen may be a modifiable risk factor for the development of malignancy in heart transplant recipients," said James O'Neill, M.D., Fellow in Heart Failure and Cardiac Tran...Unpublished trials data suggest most SSRI antidepressants unsuitable for children
... The investigators reanalysed data from randomised controlled trials that evaluated an SSRI compared with placebo in children aged 5-18 years that were published in a peer-reviewed journal. The analysis was extended to include data from unpublished trials (made available from the UK Committee for the Safety of...