U of MN researchers set new standard of care for adult cord blood transplant patients
...present the promising results from adult umbilical cord blood studies for patients with cancers of the blo...ll Institute. A major limitation of adult cord blood transplantation highlighted in the NEJM articles is the high likelihood of patients dying earl...First-ever safety study of medical cannabis use in Canada launched
...ASS will typically have pain resulting from spinal cord injuries, multiple sclerosis, arthritis or other kinds of hard-to-treat neuropathic or muscle pain," explains Dr. Mark Ware, principal investigator and pain physician at the McGill University Health Centre (MUHC) Pain Centre. "We are not recruiting c...Kinder, gentler procedure gives superior results for stem cell transplants
...s from donor marrow, peripheral blood or umbilical cord blood, the procedure allows early recovery of immune function, nearly eliminates transplant rejection, and decreases the incidence and severity of "graft vs. host disease," a common complication in transplants. Termed a "reduced-intensity" protocol,...UGA researchers receive NIH contract to create a stem cell-based drug assay for SMA
...2 are not enough to keep the neurons in the spinal cord from degenerating. Transgenic mouse models, developed to study SMN function, have been informative, said Stice. However, typical model systems, such as the mouse, possess only one SMN gene and research has found that the initial survival of human SMA...First blood test to diagnose paralyzing, blinding disease
...ble time. NMO affects the optic nerves and spinal cord -- and within five years causes half of affected p...e MS. MS is not confined to optic nerve and spinal cord involvement. However, the symptoms of the two diseases overlap, and optic nerve and spinal cord invo...Veterans in better health than other residents of nursing homes, new test for evaluating tinnitus
... rehabilitation therapy in Rome, Italy, for spinal cord injury, Parkinson's disease, depression, or stroke...k, such as the elderly and individuals with spinal cord injury. Patient controls loudness and pitch during new diagnostic test for tinnitus Th...Mayo Clinic Cancer Center receives SPORE grant for brain cancer research from NCI
...rm of tumors that originate in the brain or spinal cord tissue rather than those that spread to the brain from other areas of the body. "Adult gliomas can have a disproportionately greater effect on a person's quality of life than more common cancers because they can significantly disable cognitive, memor...Spinal cord injury patients show improvement in early device study
INDIANAPOLIS Treatment for spinal cord injury leading to paralysis continues to stymie ph...en patients with complete motor and sensory spinal cord injury were implanted with an experimental device designed to regenerate nerve fibers, promoting som...Spinal repair pioneer to speak in NY on 20th Jan
The first clinical trials seeking to repair spinal cord injury on a pilot group of selected patients are s...search has raised the real possibility that spinal cord injuries, long considered incurable, could be repaired. The work of the team holds out significant h...Cord blood transplantation now a viable option for adult leukemia patients
..., 2005) Stem cell transplantation using umbilical cord blood is a standard treatment option for blood dis...nnesota examined a new technique that combines two cord blood units from different donors for transplantation into adult or adolescent leukemia patients. Th...Researchers discover genetic variant that may explain why women develop M.S. more than men
...al disease of the covering of the brain and spinal cord that disrupts nerve transmission. It is caused by a combination of genetic factors -- there is not a single MS gene -- and is also believed to be influenced by various factors in the environment. MS is diagnosed in an estimated 400,000 people a year ...Nanoscale diagnostic sets sights on Alzheimer's
...s analyzing fluid from around the brain and spinal cord have detected a protein linked in recent studies to Alzheimer's disease. If proven successful in further clinical studies, the procedure could become the first tool for early diagnosis of Alzheimer's, and the first test to conclusively identify the d...Promise of 'bladder pacemaker' for people with spinal cord injury
...the more than 200,000 Americans living with spinal cord injury (SCI) or disease-related spinal cord problems. Neural engineer Warren Grill and biomedical engineering doctoral candidate Joseph Boggs fo...News Tips from the Journal of Neuroscience
...y of obstacles to neuron regeneration after spinal cord injury. This week, Fouad et al. adopt a multifacet...o optimize regeneration in adult rats after spinal cord transection....Inflammatory cells highly promising target in NF 1
...such as the sciatic nerve that connects the spinal cord with the leg and foot muscles. The tumors can interfere with the function of the brain and other organs, or prevent patients from walking. "Those are particularly tough problems. They're very challenging to treat surgically, and radiation and chemoth...Infectious agent linked to mad cow disease found in organs other than the brain
... Past research had shown that the brain and spinal cord bear the highest infection risk for BSE, followed by organs such as the spleen, lymph nodes and tonsils. All other organs were thought to be devoid of prions. Ruddle and co-authors analyzed three organ systems that are typically free of prions: liver...Stem cell therapy for spinal injury
... encourages the growth of pain axons in the spinal cord by secreting substances that stimulate neuronal development. The researchers found that the presence of neurogenin-2, a "transcription factor" that regulates the activity of other genes during the stem cell maturing process, inhibited the development...Uric acid may help reduce effects of spinal cord injury, Jefferson researchers find
...ry" cellular damage that occurs following a spinal cord injury, say researchers at Jefferson Medical Colle...o new treatments for such injuries. After a spinal cord injury, the body's inflammatory response may actually make things worse, releasing a variety of pote...Mothers' exposure to air pollutants linked to chromosome damage in babies
...romosomal abnormalities were measured in umbilical cord blood by a "chromosome painting" technique called fluorescence in situ hybridization, one that enabled researchers to observe the structural changes within the chromosome. Chromosomes are the threadlike packages in the nucleus of the cell that contai...... N. Thompson Regeneration in the CNS after spinal cord injury is limited because of obstacles such as glial scars and myelin-based inhibitory factors. On the other hand, axons in the PNS are much more resilient. This week, Qiu et al. provide evidence for Janus kinase (JAK)signal transducer and activator ...