Tip Sheet: Think About Your Health In April
...HumanPopulation Laboratory in Berkeley, found the cumulative experience (threedecades) of heavy drinking, smoking, lack of physical activity and depressionand social isolation and poor health led to higher rates of being frail in old age. People who were consistently physically inactive had twice the riskof b......has had worse than grade 2 neuropathy despite high cumulative doses ofcisplatin and paclitaxel. It is also enco...ptothecin derivatives. Inaddition, no evidence of cumulative toxicity has been observed in the animalstudies conducted with karenitecin. Karenitecin is in Phase ...Intestine Transplant Results Reported At American Society Of Transplantation Meeting
...lanted in the last four years, for whom there is a cumulative 65percent survival rate. Thirty-five patients are alive and able to maintain good nutrition for more thanthree years, and 22 are beyond the five-year milestone. One patient whoreceived a small bowel and liver has survived nearly nine years. In the ...Stress Speeds Progression To AIDS
...mulative stressful events and the men who had less cumulative social supportwere the ones who progressed faster ...ial support. "We showed that for every increase in cumulative average stressful life events -equivalent to one severe stressful event or two moderate stressful ev...Stress speeds passage from HIV to AIDS, support retards it
...ine reports. "We showed that for every increase in cumulative average stressful lifeevents -- equivalent to one ... Leserman said that the finding with regard to the cumulative effects ofstressful life events "is perhaps among the most compelling evidence to datelinking psycho...... inearlier non-L&I sponsored studies with a higher cumulative dose and/or different initialschedule. "As clinicians, we are very pleased with these results. They predict a muchbrighter future for this patient population," said Dr. Keating. "While none of ourtherapies are curative, it appears that CAMPATH may ......ing and that treatment should be discontinued at a cumulative dose of 140 mg/m2. Today's recommendation by the Peripheral and Central Nervous System Drugs Advisory Panel, although not binding, will be considered by the FDA in its final review of the NOVANTRONE new drug application (NDA). The committee that rev...New study finds multiple myeloma linked to radiation exposures of nuclear workers
...ompared them to health records. Older workers with cumulative radiation doses of five rem or more were almost th...iple myeloma than workers at the same plants whose cumulative exposures were less than one rem. The current occupational limit for radiation workers is five rem ...Dietary bioflavonoids induce DNA breaks, may contribute to infant leukemia
.... Combinations of these substances demonstrated a cumulative effect. Another group, the flavanones, found in citrus fruits, did not induce MLL cleavage. "The public health message from this study is not yet clear," said Janet Rowley, M.D., Blum-Reise Distinguished Service Professor in the departments of ...Antidepressants impair cognitive function in the elderly
...gs such as antidepressants have both immediate and cumulative negative effects on cognitive performance for people age 80 and over. "These kinds of medications are often prescribed to improve cognitive function. However, this study showed the opposite result. In addition, these drugs are also already associat......en million prescriptions have been written and the cumulative number of patients who have received AVANDIA is approximately two million.......act, the authors write, "An organization with less cumulative experience than its rivals can still achieve a per...s to evaluate the data. The results confirmed that cumulative experience is a significant predictor of learning, and further reveal that the slope of the learning...Low-dose combo no better than aspirin alone in secondary prevention
... informational biases that might have affected the cumulative number and classification of reported bleeding episodes, Fiore says.According to the American Heart Association, about 530,000 Americans die from heart attacks and other forms of CHD each year. Aspirin may increase the incidence of gastrointestinal ...Testicular cancer - cure rates now so high patients may be more at risk from treatment
...sks. The chemotherapy administered, especially the cumulative doses of doxorubicin and cisplatin, were not consi...ther they had additional radiotherapy and to their cumulative dose of the drug cisplatin. Twenty-five patients displayed long-term impaired renal function 23 of...New awards, expanded focus for Pediatric AIDS Clinical Trials Group
... Disease Control and Prevention reports that 4,219 cumulative cases of AIDS among adolescents, or children ages 13 through 19, were reported through June 2001,(1) and the number of adolescents living with HIV is estimated to be much higher. Because the average length of time between HIV infection and the deve...Swedish trials suggest modest benefit for screening mammography
...in women aged 50-54 years. The benefit in terms of cumulative breast cancer mortality started to emerge at about 4 years after randomisation and continued to increase to about 10 years. There was no significant difference in death from all causes between screening and control groups. Lennarth Nystrom comments: ...Arsenic in well water related to atherosclerosis
...erage arsenic concentration in that water, and the cumulative arsenic exposure were significantly associated with prevalence of carotid atherosclerosis in a dose-dependent relationship (meaning the amount of disease increased as the amount of arsenic increased). Researchers divided subjects into three groups b...Study observes no association between cell phone use and auditory tumors
...nfrequent users. No association was observed with cumulative use, and we found no evidence of a trend in the odds of risk with increasing levels of exposure. There are no established environmental causes of acoustic neuroma, although there has been concern that hand-held cellular telephone users may be at in...Firstborn: First risk for heart disease?
...ette smoking was lower among the firstborns. The cumulative number of risk factors per patient was almost identical between the firstborns and their younger siblings.Because we found the same kinds of risk factors in both groups, we suspect primogeniture is the likely explanation and should be regarded as a d...New hope for treating or avoiding heart failure after cancer drugs
...hat cardiotoxicity was closely correlated with the cumulative dose. However, there was a striking variation among the patients and a dramatic increase in susceptibility in older patients. They detected a progressive decrease in cardiac function beginning three months or more after the start of chemotherapy. Th...