Environmental inequities cluster to harm poor children
... air, water or crowding, are typically modest, the cumulative effect of multiple-risk exposures is highly significant. "To make a difference, we need to take a broader perspective for intervention. When we look at the medical needs of low-income children, for example, we have to look at their housing. When we...Extended lymph node dissection fails to increase long-term survival among gastric cancer patients
... the morbidity, mortality, long-term survival, and cumulative risk of relapse of a limited (D1) lymph node dissection to an extended (D2) lymph node dissection for gastric carcinoma in a randomized trial. A total of 1078 patients with gastric adenocarcinoma were randomized to undergo D1 or D2 dissection, o...Tacrolimus + mycophenolate mofetil & steroids: Safe, effective in preventing acute cardiac rejection
...lications, malignancies, adverse drug effects) and cumulative total dose of steroids and doses at six and 12 months. After six months, initial study results show a few trends emerging, while other measurable objectives are undifferentiated between the three therapy regimens. There appeared to be no di...Dental X-rays during pregnancy associated with low birth weight babies
...). For their analysis, the authors categorized the cumulative radiation exposure into three dose groups: 0 mGy (... (which corresponded to the 90th percentile of the cumulative radiation doses among women who had at least one dental x-ray.) Among the women who delivered a LBW ...Frozen, fresh sperm both effective for in vitro fertilization
...eness of fresh vs. frozen sperm by calculating the cumulative live birth rate -- that is at least one baby born ...ransfer cycles. For cycles using fresh sperm, the cumulative live birth rate was 51.6 percent. For frozen, it was 53.1 percent. Dr. Thornhill says Mayo Clinic d...Ganciclovir (Valcyte/Cymevene) reduces risk of cancer in kidney transplant patients
...sease (PTLD), cancer of the blood, showed that the cumulative length of ganciclovir treatment is significantly associated with a lower risk of developing PTLD, compared to those with no antiviral therapy. There was no such effect for patients on acyclovir.1 Further results from the multicentre case-control stud...Patients not sticking to cholesterol drugs -- and the higher their co-pay, the lower their use
...armacy claims, they calculated a quantity called a cumulative multiple-refill interval gap, or CMG, for each patient, to determine what percentage of days the patients were without enough pills to adhere to their treatment regimen. Any patient who was without enough pills for one day out of 10, or ...VELCADE(TM) data confirms long-term survival
...lar to those in phase II trials and no evidence of cumulative or permanent toxicity was reported with continued therapy. High does dexamethasone was part of therapy for 75% of patients during the parent and extension trial. Trial results also confirm that VELCADE TM and dexamethasone can be safely combined. ...Northwestern Memorial named one of nation's top 12 hospital-affiliated infertility clinics
...ition," said Dr. Kazer. "Our success reflects the cumulative efforts of a large and dedicated group of individuals." Northwestern's team, comprised of five full-time physicians and three Ph.D.'s, provides a wide range of clinical services for women with various gynecologic, hormonal and reproductive disorder...Women who early in life care for elderly parents are at higher risk of poverty later
...creating losses in working hours and earnings. The cumulative effect of this scenario contributes to elderly women's disproportionately higher risk of living in poverty. In 2002, 14 percent of women who are 75 or older lived in poverty, but only 8 percent of comparably aged men lived in poverty. The Health and...Certain components of the brain's 'executive functions' are compromised early in abstinence
...al effects from their acute consumption as well as cumulative effects from their chronic drinking. All of the study participants were male veterans receiving treatment at the Durham Veterans Affairs Medical Center. Researchers administered memory and executive-function tests to two groups, alcohol-dependent p...Smoking and the risk of rheumatoid arthritis
...mer smokers tend to have a wide variation in their cumulative smoking history, the researchers chose to restrict their analysis to current smokers and men and women who had never smoked. The DNA samples of the RA patients were studied for evidence of genes for the SE. The SE is a protein sequence found in cel...Asymptomatic cardiovascular changes are powerful predictor of future heart disease
... one point in time, the index of measures reflects cumulative vascular burden that can more accurately point to later risk for coronary artery disease," Dr. Kuller continued. "Earlier interventions, perhaps with drugs to treat cholesterol and hypertension, as well as controlling diabetes and making modification...Heavy, lifetime alcohol users may be toasting metabolic syndrome
...ses the risk for cardiovascular disease. "Lifetime cumulative effects of alcohol consumption on cardiovascular risk factors comprising the metabolic syndrome have been largely unknown, but our study found that drinking patterns independently predict the risk of metabolic syndrome," said lead author Amy Z. Fan, ...Proposed addiction treatment successful, safe in second small trial
...part because some epilepsy patients who have taken cumulative doses in excess of 1500 grams have experienced a reduction in their field of vision. The current study was designed to look for such visual side effects while testing the efficacy of a relatively low GVG dose. In response to word-of-mouth and newspap...Panel offers recommendations for monitoring adverse events from dietary supplements
...outinely use dietary supplements, accounting for a cumulative $18 billion per year in sales....Compound in apples may help fight Alzheimer's disease
...duce free radicals (oxidants) that appear to cause cumulative damage to brain cells, according to some researchers. Although theres no cure for the disease and no one is sure of its exact causes, some researchers are increasingly optimistic that dietary intervention using antioxidant-rich foods might help reduc...Proposed addiction treatment successful, safe in second small trial
...part because some epilepsy patients who have taken cumulative doses in excess of 1500 grams have experienced a reduction in their field of vision. The current study was designed to look for such visual side effects while testing the efficacy of a relatively low GVG dose. In response to word-of-mouth ...NHLBI stops sickle cell anemia transfusion study
...al hemoglobin. Transfused patients who received a cumulative dose of 250 ml/kg of blood began to develop iron overload and were given chelation therapy. Chelation involves subcutaneous infusions of deferoxamine, a drug that removes the iron. After 79 patients had been enrolled in the study, the STOP II Data...Accumulated lead exposure may be an important risk factor for cataracts
...r pipes. Results of the present study suggest that cumulative lead exposure is a risk factor for cataract, which accounts for more than 40 percent of all cases of blindness worldwide," the authors write. They add that expenditures for cataract surgery comprise the largest single line item in the Medicare budget...