Stem cells of limited use for cardiac muscle repair
...hat the injected cells located the areas of muscle damage and insinuated themselves, sometimes as separate cells and sometimes by fusing with muscle cells. In neither case, though, did they produce sarcoglycan, a reliable marker of mature muscle cells. When the researchers repeated the experiment wi...MRI-guided ultrasound therapy relieves symptoms in patients with uterine fibroids
..." Dr. Gedroyc said. One patient had sciatic nerve damage with pain and mild weakness, but this resolved itself quickly. One patient was kept overnight because she had a reaction to the sedation she was given, Dr. Gedroyc said. "There were several instances where patients had prolonged menstrual bleeding, b...Other highlights in the December 1 JNCI
...provided evidence that the chemical may be able to damage DNA. To evaluate the incidence of cancer among pes...anoma A reduced capacity to repair UV-induced DNA damage has been associated with an increased risk of cutaneous malignant melanoma, but the molecular mechan...Wipeout! Surfing creates wave of unique injuries
...ed head and neck trauma, broken arms and legs, and damage to the knees. Environmental injuries included foreign matter in the lungs, damage to the ear canals from exposure to cold water, lacerations from surf board fins, and stings and bite...Antibiotic rifampicin shows promise for fighting Parkinson's disease in lab tests
...nting fibril formation and associated neurological damage in patients with Parkinson's disease, said Anthony Fink, professor of chemistry and biochemistry at UCSC. "Clearly, more work is needed to determine if this would work therapeutically, but if it does it would probably be most useful as a prophylac...Stem cells' repair skills might be link to cancer
... cells gone awry in their efforts to repair tissue damage could help explain why long-term irritation, such ...eartburn) erodes the lining of the esophagus. That damage triggers a repair process that requires tissue-specific stem cells to gather, multiply and eventuall...FDA grants accelerated approval of TYSABRI, formerly antegren, for the treatment of MS
... where they can cause inflammation and potentially damage nerve fibers and their insulation. "TYSABRI is a powerful and innovative therapy that offers new hope for hundreds of thousands of people living with MS," said James C. Mullen, chief executive officer, Biogen Idec. "We believe TYSABRI will revolu...System that regulates blood pressure may also affect aging
...ls, or molecules with unpaired electrons, that can damage cells. In rats, Robbins tested a blood pressure medication that blocks the effects of angiotensin II. Early results show that the drug has the potential to combat oxidative stress and reduce cognitive impairment....Chronic back pain shrinks 'thinking parts' of the brain, study finds
...pathic -- exhibiting pain because of sciatic nerve damage -- and non-neuropathic. Brain scans showing gray matter volume were compared. In earlier research, Apkarian and colleagues found that back pain sustained for six months or longer is accompanied by abnormal brain chemistry, indicated by chemical chan...Examination of possible conflicts of interest to influence look at suspected adverse drug reactions
...d the risk of rhabdomyolysis (a disorder involving damage to muscle tissue) to illustrate the operation and limitations of the current U.S. postmarketing safety-surveillance system. "Soon after marketing [of cerivastatin], spontaneous reports identified cases of rhabdomyolysis, an uncommon condition in whic...Study helps define headaches of whiplash
...umption that a rear-end collision will do the most damage to the back of the head and neck, Dr. Kumar said. They also found that mere awareness of an impending impact reduces the head-neck acceleration by 40 per cent, mitigating the risk of injury. "Based on scientific evidence, we can now show there is a c...Pet scans detect brain differences in people at risk for Alzheimer's
...that APOE- 4 carriers have to compensate for early damage done by Alzheimer's by switching to an alternate brain network to complete the task. It could also be that their different genetic makeup results in different patterns of brain activity. In previous studies, Dr Scarmeas has demonstrated APOE-related...Cocaine addicts show reduced brain structure that underlies judgment
...la changes might represent changes in the brain or damage resulting from drug use. However, they said "An alternative hypothesis is that the observed amygdala abnormalities are a developmental condition that predisposes subjects to cocaine abuse or addiction." They pointed out that the normal relationship i...Hong Kong think tank calls for pollution standards
...n lead to reduced lung capacity and permanent lung damage according to the EPA. "Many in Hong Kong thought almost all the ozone in the area was coming from mainland China," said Bergin. "Our results suggest organic compounds that lead to ozone formation may have sources in and around Hong Kong. Hence solvi...An apple a day could protect against brain-cell damage
...in apples could protect the brain from the type of damage that triggers such neurodegenerative diseases as A...g the production of reactive substances that could damage normal cells. "The studies show that additional apple consumption not only may help reduce the risk ...Infection puts extremely low birth weight infants at risk for developmental delays
...event infection and to prevent such nervous system damage from occurring once an infection had occurred....No link found between pneumonitis in breast cancer patients and taxane-based chemotherapies
...arch and the earlier study that suggested the lung damage correlation was, in the M. D. Anderson study, chemotherapy and radiation were given sequentially, compared to simultaneous delivery in the smaller study. "It is possible that taxanes and radiation given simultaneously interact to cause increas...Compound in apples may help fight Alzheimer's disease
...en peroxide to simulate the type of oxidative cell damage that is believed to occur with Alzheimers. These r...were treated with quercetin had significantly less damage to both cellular proteins and DNA than the cells treated with vitamin C and the cells that were not ...Chemoprevention backgrounder: Working for a future of cancer chemoprevention
... their risk of developing lung cancer, the genetic damage caused by smoking does not entirely disappear, M. ...er ways, besides retinoids, to prevent the genetic damage from turning into cancer. One of the most promising approaches to lung cancer chemoprevention is the...Prenatal alcohol exposure has effects far beyond fetal alcohol syndrome
...aging procedures to help target when and where the damage occurs. By also identifying critical moderators o...ndividuals and thus better understand the specific damage and mechanism by which this damage occurs. We have also collected data on a genetic polymorphism in...