Computational tool predicts how drugs work in cells, advancing efforts to design better medicines
...ool, first using a reverse-engineering approach to decipher the multitude of regulatory networks operating among genes in a simple organism, then testing the ability of the resulting network models to predict gene and pathway targets for a variety of drug treatments. Finally, they used the tool to predict th...Marijuana-like compounds may aid array of debiliating conditions ranging from Parkinson's to pain
...lls. As a next step, the researchers will further decipher the mechanisms of action of THC and cannabidiol. Another animal study also indicates that a marijuana-like compound can protect brain cells from the damage produced by the disorder Parkinson's disease. "For the first time, our research shows the ne...New understanding of neural circuits may help development of thought-controlled prosthetic devices
...n and spinal cord. Once a mystery, new studies now decipher some of this complex chatter. The new research ...the progress in the basic science fields that help decipher neural circuit communication. One new analysis that decoded some circuit activity may help sim...Scientists raise caution about effects of HRT on hearing
...it was in complex settings such as the ability to decipher a sentence while listening to someone amid a loud backdrop, like the cacophony at a cocktail party that the HRT group fared worst. "It's important to alert women that there could be another significant side effect of hormone-replacement therapy," s...Air pollutants alone may cause asthma attacks
...ike condition. In these cases, it was difficult to decipher the extent to which pollutant particles, allergens or other factors contributed to the airway inflammation. This study introduces new and more rapid screening models that better isolate the biological mechanisms behind an acute asthma attack. This t...Monkeys consciously control a robot arm using only brain signals
...recording and analysis system that enabled them to decipher brain signals from owl monkeys in order to control the movement of a robot arm. The latest work by the Duke researchers is the first to demonstrate that monkeys can learn to use only visual feedback and brain signals, without resort to any muscle mov...Research offers insight on treatment for hereditary eye disease
...s to pinpoint the mutations, which enabled them to decipher which of rhodopsin's 348 amino acids were distorted. The first technique used, compensatory mutations, is a method of inserting different amino acids into a protein to instigate change and tracking where the repercussions occur. Researchers then m...Faulty gene may explain why some fall ill at high altitudes
...oxide in their lungs. "We did this study to try to decipher the genetic cause of the nitric oxide deficit in patients with HAPE," Hanaoka says. Researchers drew blood from 41 healthy climbers with a history of HAPE and a control group of 51 healthy climbers from the Mountaineering Association of Nagano and th...Buszaki neuroscience research published in current journals 'Science' & 'Nature'
...the most fundamental problem of neuroscience is to decipher the code which the neuron uses to encode its message into a sequence of electrical events," said Buzsaki. His collaborator, Ken Harris, notes that evidence over the last decade "strongly suggests a temporal code is employed, and that the precise rhyt...Area of brain found to play key role in initiating memory storage
...back to the medial geniculate, allowing neurons to decipher the significance of the sounds.This work puts the amygdala in the middle of the circuitry, in a very prominent position in terms of relevance toward learning, Gabriel said. The findings, he added, also are consistent with a theory originally formula...'Handwriting challenged' doctors to take penmanship class at Cedars-Sinai Medical Center
...ntly featuring a contest where our doctors have to decipher the handwriting of two anonymous colleagues. The grand prize is Sunday Brunch for two at the Four Seasons Hotel in Beverly Hills." The strategy worked. Dr. Hackmeyer says that Cedars-Sinai physicians have responded enthusiastically to the class a...To help people decipher the bewildering maze of cancer information on the WorldWide Web and to empower patients and families to work as effective partners withtheir health care providers, four Boston-based organizations are offering aunique two-day program called "Demystify...