First mouse model for multiple system atrophy points to new treatment targets for brain diseases
...culties, and blurred vision. Most patients develop dementia late in the course of the disease, which is usually diagnosed in people over 50. Currently there is no specific drug to treat the myelin and nerve damage caused by the protein inclusions. Parkinson's disease drugs and others are used to alleviate ea...Chemical decoy shows promise for slowing Alzheimer's by acting as decoy
... one." Alzheimer's is a chronic, incurable form of dementia that primarily strikes the elderly and causes severe memory loss and eventually, death. A complex disease with many probable causes, it is most often characterized by the presence of senile plaques and tangles in the brain, which are seen upon autops...Dealing with conflict in caring for the dying patient
...hts the case of an 84-year-old woman with advanced dementia whose advance directive states that she does not want artificial nutrition or hydration. Over the course of her illness, her family and physicians conflict about the use of a short-term feeding tube and intravenous hydration. From this case study, a...University of Manchester awarded 826k for brain science and mental health research
...ence to our understanding and treatment of stroke, dementia and mental illness." The call for research proposals followed two themes: 'Pathfinders', to develop novel and exciting research ideas for laboratory and population-based studies, and 'Trial Platforms' to build capacity for large scale clinical trials...New trials for counseling caregivers and patients with Alzheimer's begin
...y people with Alzheimer's, the most common form of dementia affecting people over 65. Dr. Mittelman and her colleagues found that a unique counseling and support program substantially eases the depression of spouse caregivers of Alzheimer's patients, and the effects were evident even three years after counsel...Drugs used to treat Alzheimer's in nursing homes are worsening sufferers' illness
...at agitation, a common and distressing symptom of dementia (a catch-all term for diseases such as Alzhimer's....authors. The study looked at 93 patients with dementia across the north east of England over six months. Those in the study taking quetiapine experienced...Hormone therapy controversy raises drug safety issues
...ost common health issues for women heart disease, dementia and osteoporosis, write the authors. "The intent was good," said Naughton, an associate professor of public health sciences. "There was some evidence showing the drugs might be beneficial for heart disease and dementia," she said, "but the WHI, a lar...UT Southwestern doctors track Oklahoma Alzheimer's patients via telemedicine
...ry studying the clinical and scientific aspects of dementia in the American Indians. "After finding out that ... Alzheimer's-related memory loss or other types of dementia within the Choctaw community. Dr. Weiner first used the satellite link in January to see patients. T...Contrary to previous findings, smoking is detrimental to patients with Alzheimer's
..., progressive disease and the most common cause of dementia among the elderly in the United States, affecting 4.5-5 million adults -- 10 times more than those affected by Parkinson's disease. The disease is marked by the accumulation of two distinct brain lesions -- beta-amyloid plaques and neurofibrillary ta...No magic pill for treating dementia symptoms
...n, delusions and other symptoms that can accompany dementia are not effective, researchers from Wake Forest Un... delusions that are observed in most patients with dementia at some point in the illness," said Kaycee Sink, M.D., lead researcher. "There is no clear standard ...New test is first step in early detection of Alzheimer's disease
...efore plaques and tangles develop in the brain and dementia sets in. A study by the Northwestern team shows that bio-bar-code amplification (BCA) technology, which was developed at the University, can detect in human cerebrospinal fluid (CSF) miniscule amounts of a toxic protein that may be responsible for ...Cardiovascular risk factors in midlife strongly linked to risk of dementia
...le age may also increase significantly the risk of dementia in old age. The study of nearly 9,000 northern Cal...sociated with a 20 to 40 percent increased risk of dementia in later life. Compared to those with no risk factors, those with two of the risk factors were 70 pe...Moderate alcohol intake may reduce risk of dementia in older women
... study to assess the effects of hormone therapy on dementia and cognitive function. As part of the study, wome...derate levels of alcohol intake reduce the risk of dementia and decline in cognitive function. Espeland said, however, that the results must be interpreted with...Weight loss may be an early sign of dementia in the elderly
...eight loss begins before the onset of the definite dementia symptoms and accelerates by the time of the diagno...can men included 112 men with incident [new onset] dementia and 1,778 without dementia. The study participants were examined on six occasions over a period of...NIH halts use of COX-2 inhibitor in large cancer prevention trial
...ecoxib for the prevention and treatment of cancer, dementia and other diseases. In light of these new findings, NIH Director Zerhouni requested: a full review of all NIH-supported studies involving this class of drug. NIH Institutes to inform the principal investigators for all of these studies and will as...To help your mind, take steps to help your heart, study says
...about a condition called mixed dementia. Mixed dementia is a combination of Alzheimer's disease and vascul...ain, making strokes more likely. Strokes can cause dementia through the death of large areas of brain tissue, or through the build-up of damage from multiple sm...Rolipram - a potential new treatment for Alzheimer disease
Alzheimer disease (AD) is the most common form of dementia in the elderly and classic clinical features include memory loss, deterioration in speech, and behavioral disturbances. Doctors increasingly concede that central to the cause of AD is the production and accumulation of beta-amyloid (Ab), which is tox...Long-term obesity linked to loss of brain tissue in women
...udy indicates that a high BMI is a risk factor for dementia in women. Other studies have reported similar find...ealthy vascular system, and therefore, to a higher dementia risk," said Gustafson. "Obesity may also increase the secretion of cortisol, which could lead to atr...Hiding drugs in food in nursing homes is common
... patients in 90 special care units for people with dementia in Norway. If any drugs had been concealed in the food or beverages during the previous seven days without the patient's knowledge or consent, it was recorded, along with the reason for hiding the drugs. They found that 11% of the patients in regular...Pet scans detect brain differences in people at risk for Alzheimer's
...nts, mostly in their 60s and 70s, had any signs of dementia or memory deficits and the two groups could not be distinguished from one another by standard cognitive tests. PET scans taken while the subjects were performing a memory task, however, showed clear differences between the two groups. As the particip...