Tag: "demonstrate" at medical news

Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop

...ported today in the journal Nature,is the first to demonstrate how leptin initiates the burning of stored fat, a process thathas been postulated but never proven. In fact, their study shows that leptinis only the first step in a series of events that ultimately boosts fatmetabolism, according to study authors Sh...

Tacrolimus Stops Rejection Of Kidney Transplants

...lantation. This is the first multi-center trial to demonstrate such encouraging results for persistent kidney rejection. The study, which involved 73 patients who entered the trial between September, 1993, and May, 1994, is reported in the September 15, 1996, issue of Transplantation. Tacrolimus rescue therapy, ...

Nasal Spray Flu Vaccine By U-M Researcher Is 93% Effective

...ology from the U-M. "The clinical trials demonstrate that the vaccine is safe, immunogenic,genetically stable and highly effective. It is very gratifying to see our yearsof effort pay off this way," said Dr. Maassab, who has been collaborating withNIAID on the vaccine since 1973. Maassab, now age 70,...

"Super Aspirin" Holds Long-Term Benefits For Some Patients Who Undergo Balloon Angioplasty

...nal of the American Medical Association (JAMA) demonstrate a favorable effect on long-term outcome and survival in selected patients treated with ReoPro™. In an editorial that accompanies the study, David L. Fischman, MD, associate professor of medicine, division of cardiology, Jeffers...

BioNumerik Reports Preclinical Antitumor Data On Two Novel Supercomputer Engineered Anticancer Agents At 89th Annual AACR Conference

...sting camptothecinderivatives. These results also demonstrate the ability of BioNumerik'sKarenitecins to bypass common drug resistance mechanisms (MDR, MRP & LRP) towhich many other camptothecins appear to be susceptible. Because its compoundsare lipophilic, BioNumerik believes its Karenitecins will have enhan...

UB Plants "Seeds" By Investing In Research Projects; Researchers Leverage Investment 14 Times Over

...work across traditional disciplinary boundaries to demonstrate preliminary results that they then can present in proposals to external funders. Among the program's success stories are: o A $1.3 million grant to Lockwood and Richard Salvi, Ph.D., professor of communicative disorders and sciences, from the Nation...

Metrifonate, A New Alzheimer Drug, Helps Behavior Problems

...atients who take drugs in thisclass seem brighter, demonstrate more initiative and are easier to get alongwith in general," says John C. Morris, M.D., the Harvey A. and Dorismae HackerFriedman Professor of Neurology at Washington University School of Medicine inSt. Louis. "This is the first controlled study to d...

Study Leads To New Standard Of Care For Treating Unstable Angina: Heart-Attack Risk Reduced By 47% With Use Of Tirofiban

... 30% risk-reduction at thirty days. "Thesenumbers demonstrate very clearly the effectiveness of including tirofiban in thestandard of care for treating patients with angina," notes Herrmann, who servedas principal investigator for the Penn portion of the world-wide study. On the basis of the study resu...

Prevalence Of Silicosis Studied In Surface Coal Miners

...nia than any other state.The results of this study demonstrate that silicosis is prevalent in surfacecoal miners in western Pennsylvania and suggest the need for increasedenvironmental controls and safety practices to help reduce the risk of acquiringsilicosis. This disease is preventable," states Stauffer. "Our...

New Data Show Dangerous Interaction Between Blood Pressure Drugs

...pital emergency departments. The four case studies demonstrate the potential hazard of beginning treatmentwith one of the older CCBs on patients who are already taking mibefradil and a-blocker, according to the researchers. They write: "These patients had othermedical conditions and other medications -- which m...

By Losing (Molecular) Weight, A Clot-Dissolving Drug May Be In Better Shape To Help People Avoid A Repeat Heart Attack

...s in peopleafter a heart attack. "Our data do not demonstrate a causal relationship between the changes of vonWillebrand levels and the clinical efficacy of enoxaparin in patients withunstable heart disease," says Montalescot. "At the present time we have fewgood explanations for this excess of efficacy of eno...

New Data Show Evista Reduces Spinal Fractures

...emented with calcium andvitamin D. "These findings demonstrate that Evista may provide women with a safe new choicefor the treatment of osteoporosis," said Ettinger. "If a woman's bone massdeteriorates to the point where she has one fracture, she has a very high riskfor sustaining another fracture. By intervenin...

The Visible Humans: Coming Of Age

...Human male. They will show animations of these and demonstrate how this technology can be used to morph the male into various body sizes.) Because this is "virtual prototyping," created on a computer without building physical models of the devices, EAI's morphing software is expected to save considerable time an...

University Of California San Francisco Dental School Launches Pilot Program For Pre-Dental Students

...e dedicated to the idea of becomingdentists -- and demonstrate a willingness to work in disadvantaged communities... health programs in the commy. Applicants often demonstrate that commitment through their activities,frequently by working as leading volunteers or health worke...

BioNumerik Reports The Supercomputer Supported Discovery Of New, Non-Toxic Chemotherapy Protecting Agent

...such as BNP7787. The reported preclinical studies demonstrate thatBNP7787 appears to substantially protect against the common major toxicities ofplatinum chemotherapy and does not interfere with the antitumor activity ofcisplatin. There also appears to be reproducible evidence of enhancement ofcisplatin's anti...

UNC Researchers Find Drug-Resistant HIV In Semen

...thiscan happen," he says. "It is also the first to demonstrate that if men, andpresumably women, do not have adequate suppression of their virus, as measuredby levels of the virus in their blood, they are very likely to sheddrug-resistant strains of HIV in their genital secretions. And that is virusthat's availa...

'Alternative' Medicine Becoming Mainstream, UF Study Finds

...d which to date have little scientific evidence to demonstrate their effectiveness." About half of U.S. medical schools, including UF, offer elective courses onalternative therapies, Neims said. At UF, some required courses includediscussion of the topic. Additionally, a UF family practice clinic offersacupunct...

Faster Relief From Influenza Symptoms For 'High Risk' And Otherwise Healthy Patients With Inhaled Zanamivir

...e it lessdebilitating. These results convincingly demonstrate the efficacy ofzanamivir." Compared with those receiving placebo, patients taking zanamivir experiencedfewer complications (9 per cent less, p=0.037) and returned to their normalactivities faster (1.75 days faster, p=0.023). These findings were stron...

Maxim Phase II Clinical Trial Highlights Substantial Increase In Leukemia-FreeSurvival For Acute Myelogenous Leukemia Patients

... appeared promising in earlyclinical trials do not demonstrate efficacy in larger-scale clinical trials, therisk that clinical trials will not commence when planned, and the risk that theCompany will not obtain approval to market its products. Note: Maxamine®, Maxamine Therapy®, MaxVax®, and the Max...

Study Confirms Safety Of Common Heart Drug

...ug forheart failure. The study's findings clearly demonstrate that digoxin, when taken at low dosesand with blood concentrations tailored to individual patients, is far less toxicthan previously reported with higher doses, according to senior study author Dr.J. Herbert Patterson, associate professor of pharmacy...

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