NIAID study results support diluting smallpox vaccine stockpile to stretch supply
...ed making the vaccine. Trial Results The trial described in NEJM, led by co-chairs Robert B. Belshe, M.D., and Sharon E. Frey, M.D., of Saint Louis University, was conducted at three NIAID Vaccine Treatment and Evaluation Units in St. Louis, Baltimore, and Rochester, NY, and at the Respiratory Pathogens Re...More patients would refuse treatment if the outcome were impaired quality of life
...vely, no longer chose treatment. "Low burden" was described as a few days to one week in the hospital with min...tibiotics and oxygen. The high-burden approach was described as at least one month of hospitalization with many minor tests, more complex tests, and major therap...Buck researcher awarded Brookdale Fellowship
...ciate Professor Gordon Lithgow, Ph.D. Dr. Lithgow described his colleague as a man gifted not only in science, but also in communication. Dr. Gill is able to link researchers from different disciplines and encourage dialogue and collaboration, according to Dr. Lithgow. In a field that tends to split into sub-...Product Quality Research Institute (PQRI) issues first recommendation to FDA
...ysis following a science-based process development described in the PQRI proposal. PQRI also recommended that FDA revise its guidances and policies to reflect the proposed changes. In an agreement between FDA and PQRI and as stated in the PQRI by-laws, the FDA will evaluate the recommendation and either ado...Tool pinpoints acceptable pricing of combination vaccines
...uding individual and societal benefits. The tool described in the April issue of Health Care Management Science computes an optimum price for a combination vaccine to meet a manufacturers targeted market share. Primary concerns for parents, Jacobson said, are the costs of injections, the number required per...Study could lead to exercise-mimicking drug
...led by Williams is continuing to study the pathway described in this study to identify the best targets for drug discovery. They also seek to determine whether this pathway is pertinent to other tissues such as fat or even to the biology of cancer cells, Williams said. Mitochondria are fundamental to the funct...Action needed to stop 'disease mongering'
... forms of medicalising ordinary life may be better described as disease mongering extending the boundaries of treatable illness to expand markets for new products. Disease mongering can include turning ordinary processes or ailments into medical problems. For example, around the time that Mercks hair growth d...Buck Institute researcher identifies new drug targets for Alzheimers disease
...n recently cloned (BACE), the novel beta-secretase described in this paper preferentially cleaves normal APP to beta-peptide whereas BACE preferentially cleaves the Swedish mutant form of APP. Since 99% of people with AD have normal APP, this novel beta-secretase may be more relevant as a molecular target to d...... use of genetic testing for Alzheimers disease are described by Melissa Barbour and Peter Whitehouse in their Reflection & Reaction commentary article. They propose that the use of genetic testing needs to be discussed not just by academics and clinicians, but within the community as a whole. Treatment Ha...Enzyme halts muscle waste in mouse models of most-common childhood muscular dystrophy
...opmental Biology (242, 58-73), Martin and his team described the role of CT GalNAc transferase and their development of mice (called CT mice) that had the enzyme available in skeletal muscles, as well as the neuromuscular junction. These mice did not develop the DMD muscle wasting. In their most recent experim...Applied Biosystems introduces next generation production level DNA analysis systems
... infringement; (4) and other factors that might be described from time to time in Applera Corporation's filings with the Securities and Exchange Commission. Copyright 2002. Applera Corporation. All Rights Reserved. Applied Biosystems, ABI PRISM and BigDye are registered trademarks and Applera, Celera, Celera D...Male/female health differences during life's final season
...e no gender differences in the way the respondents described their health," the Penn State researcher says. "For example, men who had hypertension and had experienced a heart attack rated their health Good' as often as women who had arthritis and back problems." The researchers write: "Women reported more tot...Annals of Internal Medicine, tip sheet
...creening services in this issue of Annals, p. 641, described below.) Much as well-baby visits set aside time for concentrating on pediatric prevention issues, the editorial writer says, "annual examinations provide the opportunity to plug cracks in the system and assure that patients are getting indicated prev...'I think I can' helps shed pounds after giving birth
...ican Dietetics Association (December 2001) and is described on the Cornell University Ask the Nutrition Expert web page this month at http://www.cce.cornell.edu/food/ . The researchers also found that the more positive feelings a woman has about motherhood, the more likely she is to exercise frequently afte...Dopamine may play role in cue-induced craving distinct from its role regulating reward effects
...g the foods. For neutral stimulation, participants described their family genealogy in detail. Prior to and during food stimulation, participants were instructed to ratetheir feelings of "hunger," "desire for food," "alertness," "stimulation," and "talkativeness" on a scale of 1 to 10. Participants had fasted ...Peptide promotes new growth in injured spinal cords
...hed in Nature about this research. The first paper described the Nogo protein. The second paper detailed the receptor through which Nogo acts. This newest data demonstrates how to block the interaction and how to reverse its function pharmacologically. The synthetic peptide Strittmatter and his colleagues deve...First consensus guidelines on lightning safety issued before summer storms
...ced burns that ranged from mild to burns that were described as "hot poker or skewer" burns. Two other victims experienced fractured skulls, and cataracts developed in eight of 24 survivors. "To prevent these type of tragedies, people need to be informed about the risks associated with lightning," added Dr. C...Fit seniors better able to react when quick thinking needed, study says
... on "executive control function," or ECF, which he described as "cognitive processes which require more effort and are largely mediated by the (brain's) frontal lobes." An example of a more simple cognitive process, he said, occurs when a driver stopped at a red light proceeds automatically as the light turns ...Rush receives Magnet Award for excellence in nursing
...earning. Another example of innovative care giving described the Rush Mother's Milk Club. Since the mid-1990s this breast-feeding club has provided support and education to encourage mothers of premature infants to participate in the nutrition and feeding of their babies. Under the direction of Paula Meier, ......s believe that the pathology they saw had not been described previously and couldrepresent a unique form of interstitial lung disease. Six of the seven infants showed favorableoutcomes after being treated primarily with corticosteroids. One infant died from complicationsassociated with extreme prematurity. ...