Tag: "design" at medical news

Brain activity prior to treatment flags vulnerability to antidepressant side effects

...ring treatment with medication. The study's unique design compares brain function changes in healthy research subjects with no history of depression while taking an antidepressant vs. placebo, a pill with inactive ingredients. In addition, all participants took only placebo for one week prior to randomizati...

Research offers hope of new treatments for liver damage

...g. Exciting insights such as these will inform the design of future therapies." Further research into macrophages is set to follow and scientists will explore the role of these immune-system cells in damage and repair to other organs, including the kidney....

WISE study starts in Toulouse: 60 days of bed-rest for terrestrial female astronauts

...ttee in Toulouse has approved the integrated study design of WISE. With the European Space Agency's future plans for human space exploration, the results expected from WISE will prove valuable in planning long-duration human missions. This research will also have clinical significance on Earth, advancing k...

Scientist works on innovative treatments for brain tumors

...r the benefit of our patients." Other goals are to design tests to assist in drug development, so researchers can determine which potential drugs will be most beneficial in patients, and to learn if combining radiation therapy with drug therapy will improve results. Researchers also hope to learn how to not...

Community care tops medical care at preventing heart disease in black Americans

...community health worker and local residents helped design the types of services and activities offered. Specific requests included a welcoming, nonclinical look to the community care center, which resembled a living room and kitchen, and contained an exercise center for testing that participants used regul...

New ways to design safer & more effective topical (transdermal) drug delivery announced in the PNAS

... of fundamental mechanisms that may facilitate the design of safer and more efficacious topical drug deliver...researchers engineered more than 300 new CPEs. The design of the new CPEs was based on the researchers' understanding of the molecular forces that are associa...

Prostate cancer screening practices examined

...cancer. The initial results also confirm that the design of the massive study, which will continue until 2019, will indeed allow researchers to determine whether current screening practices reduce death from prostate cancer, according to the authors. They present their analyses in two papers, one in the Ma...

Medical molecules designed to respond to visible light that can penetrate tissue

...e been working with Theralase Technologies Inc. to design molecular systems that use light that is in the therapeutic window. Starting with a complex with known DNA cleaving qualities, they changed the light absorber unit to one that responds to the red wavelength. "Investigations into polyazine supermolecu...

2005 Basic Research in Periodontal Disease Award

...determine molecular targets for protease inhibitor design using a genome-screening approach. In the case of bacterial virulence determinants, glycosylation is likely to play an important role in interactions of the pathogen with the host. Research in this area examines the genetic machinery of glycosylation...

Computational tool predicts how drugs work in cells, advancing efforts to design better medicines

...l processes. Using this tool, drug developers can design compounds that will act on only desired gene and protein targets, eliciting therapeutic responses free of unwanted side effects. The research, which appears in the March 4 issue of Nature Biotechnology, reports on collaborative work by a team of bi...

Studies underscore genetic involvement in nicotine addiction & aggressive hostility

...With that, we will be in a much better position to design more effective treatments for addiction. This approach may also lead to treatments tailored to the 'genetic profile' of the smoker." The authors similarly determined that Chrna4 does not directly regulate alcohol intake because removal of Chrnb2, a g...

Hopkins convenes 'consensus' conference to develop blueprint for nationwide matching program

...tes will convene here March 2 to March 5, 2005, to design a national paired kidney exchange program. Paired kidney exchanges provide organs to patients who have a willing, designated donor who is incompatible. A kidney from such a donor is matched to and transplanted into the recipient of a second donor-p...

Both inherited traits and tumor mutations affect response to treatment of leukemia

...vides strong evidence that it might be possible to design ALL treatment based in part on an individual patient's inherited genetic makeup. ALL is the most common tumor in children and affects the cells of the bone marrow. Currently, gene-based individualization of treatments is based only on the genetic mut...

'Smart' immune cells kill more cancer

...by more than 90 percent. "It is very difficult to design cancer therapies that get the body's immune system to recognize and kill cancer cells that the system has ignored for a long time," says Ivan Borrello, M.D., assistant professor of oncology and director of the research, which is published in the Marc...

Pioneering nanosystems degree wins approval

...ion of basic chemistry and physics to analysis and design of devices and systems with nanoscale (one-billionth of a meter) features. He said products already featuring nanoscale properties include cosmetics and stain-free clothing. In the near future, he said, expect advanced drug-delivery systems, medical...

A safer route to school makes children more likely to walk and bike, study shows

...arlon Boarnet, chair of UCI's planning, policy and design department, and lead author of the study. "It suggests that we ought to think more about these small, strategic projects." The study is published this month in a special Active Living supplement of the American Journal of Preventive Medicine, availab...

Protein that promotes survival of stem cells might be key to poor leukemia prognosis

...d these diseases, the more likely we'll be able to design improved treatments for them. This fits into the St. Jude mission of finding cures for catastrophic diseases of childhood, such as leukemia, in order to save lives." The importance of Mcl-1 lies in the differing roles it plays in health and disease. ...

Study finds new designer drug is potent treatment for chronic myelogenous leukemia

...nger binds to Gleevec at all. Using rational drug design to circumvent these shortcomings, researchers at N.... "This is an elegant example of how rational drug design developing drugs based on a molecular understanding of cell structures and processes can be used t...

Female sex hormones play a vital role in defense against sexually transmitted diseases

... McMaster researchers are currently discussing the design of a study with infectious disease clinicians in Hamilton, which may begin in as early as the next few months. Additionally they will be looking at issues of co-infection with both HIV-1 and HSV-2 which is a big problem clinically. The two studies w...

'Marital strain' increases women's risk of death, heart disease

... associations we observed and the strengths of the design of the Framingham Offspring Study, we also believe there are some practical implications for clinical practice. While medical care providers are not specifically trained to intervene on psychosocial issues such as marital characteristics, they may b...

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(Date:7/21/2014)... PowerObjects, a professional services firm ... add-ons for Microsoft Dynamics CRM, has joined the ... group of the most strategic Microsoft Dynamics partners ... rank them in the highest echelon of the ... the Microsoft Dynamics Inner Circle have performed to ...
(Date:7/21/2014)... have a clot in their legs and are ... medication or undergo a minimally-invasive catheter-based clot removal ... difference in death rates between the two treatments, ... catheter procedure, according to a study by Temple ... a review of more than 90,000 cases nationwide., ...
(Date:7/21/2014)... The "viral reservoir" in which HIV can lie dormant ... earlier than previously thought, new animal research indicates. ... eradicate the AIDS-causing virus, said Harvard researchers working with ... presence of the viral reservoir remains the most significant ... HIV, known as HIV-1. "We found that the ...
(Date:7/21/2014)... (PRWEB) July 21, 2014 Western ... “Great College to Work For” by the Chronicle ... and also made the Honor Roll for the ... categories: Collaborative Governance, Compensation and Benefits, Confidence in ... Respect & Appreciation. , “Western University of Health ...
(Date:7/21/2014)... A new study suggests that potential help in lowering ... refrigerator. The study found that regular intake of ... supplements, may help ease the condition. Researchers looked ... probiotics and blood pressure. The studies involved a total ... pressure. People who consumed probiotics had an average ...
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