Tag: "destruction" at medical news

Normal aging versus Alzheimer's disease and the potential for prevention

...e areas are the first affected by AD, although the destruction of nerve cells continues to progress throughout all areas of the brain." "There is enormous interest in finding out what we can do to keep our brains healthy. Three NIH Institutes (the National Institute on Aging, National Institute of Mental Healt...

Drug prevents diabetes recurrence after islet cell transplantation

...F, has the potential to help prevent this cellular destruction by preserving insulin secretion by pancreatic beta cells in the presence of autoimmune attackers called inflammatory cytokines, according to U.Va. researchers. "Our findings are very encouraging and we are excited that Lisofylline worked...

U of MN research indicates why radiation therapy reduces bone cancer pain

... use, which was associated with a decrease in bone destruction and tumor burden. Treated mice demonstrated greater pain relief and had significantly less bone destruction and tumor burden than untreated mice. Recent studies have demonstrated that tumor burden and bone d...

Understanding the autoimmune response in type 1 diabetes

...s mellitus (T1DM) is the result of immune-mediated destruction of insulin-secreting pancreatic beta cells. For more than 25 years researchers have searched for an environmental agent or event that triggers this autoimmune response. Past research has suggested that T cells that react to islet beta cells can contr...

Cord blood cells proven to differentiate into heart muscle and brain cells

...igodendroctyes. These brain cells are targeted for destruction in children with metabolic diseases. Hall cultured a unit of cord blood stem cells in a flask together with growth factors, hormones and other compounds that direct stem cells toward the oligodendroctye lineage. One month later, Hall analyzed the cel...

High blood pressure in the lungs a major risk for death in adults with sickle cell disease

... chronic anemias that are caused by hemolysis, the destruction of red blood cells. This suggests that there is a distinct syndrome of hemolysis-associated pulmonary hypertension, a complication that has been reported with increasing frequency in sickle cell patients," said Dr. Mark Gladwin, pulmonary specialist,...

Combination drug therapy could substantially improve symptoms of rheumatoid arthritis

...pment in substantially reducing symptoms and joint destruction for people with rheumatoid arthritis, conclude aut...erapy was also more effective for effects on joint destruction measured by radiography-resulting in a statistically significant improvement on a score for joint er...

St. Jude Medical announces PAVE and DINAMIT clinical trial results

...hronic AF treated with AV nodal ablation (targeted destruction of the AV node, the heart tissue that conducts the electrical impulse from the atria to the ventricles), biventricular pacing produced a statistically significant improvement in cardiac function over standard right-ventricular pacing as measured by t...

A new hypothesis about Alzheimer's disease

... of it. By analogy, a tidal wave may cause massive destruction to a coastal area, but the tidal wave itself may have been caused by a distant earthquake undetected in that coastal area. Kelly and his colleagues have studied the basic biology of Alzheimer's and related diseases for many years, looking for new tr...

Study supports new theory for nicotine's protective effect against neurodegenerative disorders

...o chronic inflammation that further aggravates the destruction of brain cells. "In those at risk for Alzheimer's and other neurodegenerative diseases, nicotine may act much like the neurotransmitter acetylcholine. It may send signals to help suppress microglial immune response and limit excessive brain ...

Mechanism leading to life-threatening infection identified by UCSD School of Medicine researchers

...ic plague and typhoid fever to avoid detection and destruction by the body's normal immune response leading to life-threatening bacterial infections has been identified by researchers at the University of California, San Diego (UCSD) School of Medicine. Published in the March 18, 2004 issue of the journal Nat...

American Thoracic Society Journal news tips for April 2004 (first issue)

... infection, inflammation, and products from tissue destruction even when they have no symptoms. They noted that within the setting of excessive oxidation and inflammation in the patients, air pollution can lead to further airway irritation and injury, which, in turn, could affect the rate and extent of airway i...

Compound shows promise as vaccine-like drug for preventing type 1 diabetes

... the cascade of inflammatory events leading to the destruction of pancreatic beta cells, which normally produce insulin, and the subsequent onset of the disease. Although an increasing number of compounds are being designed to fight diabetes by targeting inflammation, the current study represents the first attem...

How cancer neutralizes T cell attack

...totoxic or 'killer' T cells because they cause the destruction of cells that display the antigen that the T cell recognizes; in this case, the melanoma-specific Melan-A/MART-1 antigen, which was discovered simultaneously by the LICR and by the NCI. What they found, when they analyzed CD8 T cells taken from perip...

UCSD researchers determine fibrin depletion decreases multiple sclerosis symptoms

...tion also delayed the onset of inflammatory myelin destruction and down-regulated the immune response. Previous studies by other investigators who used ancrod in experimental autoimmune encephalomyelitis (EAE), another animal model of MS, also showed amelioration of neurologic symptoms. In the current study, t...

Nitric oxide links bulk of sporadic and familial Parkinson's disease

... targets -- including itself -- are not marked for destruction as they should be. Second, any abnormal proteins can't be marked for destruction, either. Both failures likely contribute to protein build-up and the formation of protein gobs -- so-called Lewy bodies -- in cells that die in PD. By shutting down park...

Immune cells may play important role in progression of type 1 diabetes, Joslin researchers find

...elieve that NK cells play an important role in the destruction of beta cells, especially in rapidly progressing type 1 diabetes," Benoist said. "If NK cells are important for the progression of diabetes in humans, and we can block them, we may some day be able to exploit such a strategy to halt or slow the prog...

Stanford scientists help bring study of smallpox virus into 'molecular age'

...ealth Assembly agreed to this plan, postponing the destruction of the virus. Today, with fears that terrorists could develop the virus, researchers are using the surviving samples of virus to learn more about the disease. Relman, along with biochemistry professor Patrick Brown, MD, PhD, and graduate student K...

'Science of better' convenes operations researchers in Denver

...a team that examines the threat of weapons of mass destruction and dirty bombs. Other teams at the Center examine the threat of surface-to-air missile attacks on airplanes and attacks on the electricity system. Prof. Von Winterfeldt will be available for interview on Monday, Oct. 25, 9:30 AM, Plaza Building-Dire...

Lab study defines and blocks mechanism that lets brain tumors sidetrack immune response

...e more detectable and therefore more vulnerable to destruction by the immune system. We plan to exploit these findings by adding COX-2 inhibitors like Celebrex (celecoxib) to our clinical trials for brain tumors." "We have recognized for some time that defects in the process of antigen presentation were involve...

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